The Influence of the Procalcitonin Method in Detecting Paediatrics Infections

Sani Bajrami; Marika Mirkoska

doi:10.3889/oamjms.2026.3072

Authors

Sani Bajrami Department of Neonatology, Department of Child, Clinical Hospital, Tetovo, RN Macedonia; Faculty of Medical Sciences, Tetovo, RN Macedonia
Marika Mirkoska Department of Clinical Biochemistry, Clinical Hospital, Tetovo, RN Macedonia

DOI:

https://doi.org/10.3889/oamjms.2026.3072

Keywords:

bacterial infections, Procalcitonin, obese Egyptian children

Abstract

BACKGROUND: In daily pediatric clinical practice, in addition to the standard markers such as PCR.

AIM: We aimed to demonstrate the role of Procalcitonin in early detection of bacterial infections of the respiratory tract at pediatric age and to determine the sensitivity, specificity, VPP, PCT VNP (quantitative method VIDAS-B-R-A-H-M-S-PCT) in bacterial respiratory infections.

METHODS: The prospective, randomized study, conducted at the Clinical Tetovo Hospital (Neonatology Department - Pediatric, Clinical and Biochemical Laboratory), in the period November 2011-December 2012. It includes 99 children. The study group includes 76 children. With upper respiratory tract infections (tonsil pharyngeal) 35 cases. With respiratory tract infections (bronchopneumonia) 41 cases, control group 23 cases.

RESULTS: With tonsil pharyngeal infections, out of 35 cases (28.57% were bacterial by criterion). With respiratory tract infections (bronchopneumonia), from 41s (39.02% were bacterial by criterion). In all 35 studies with bacterial tonsil pharyngeal disease, specificity, sensitivity, PPV, NPV of Procalcitonin, which resulted in the following (88%, 90%, 75%, 95.65%), and P = 0.12. All 41 patients with bacterial bronchopneumonitis were calculated as: Specificity, Sensitivity, PPV, and NPV of Procalcitonin, which resulted in the following (72.73%, 100%, 76%, and 100%). and P = 0.12.

CONCLUSION: Procalcitonin may serve as an early marker of upper and lower respiratory infections.

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