Antiaging Activity of Gel Preparation Containing Three Varieties of Passion Fruit Peel Ethanolic Extract


  • Nazliniwaty Nazliniwaty Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Sumatera Utara, Padang Bulan, Medan Baru, Medan, Sumatera Utara 20155, Indonesia
  • Fathur Rahman Harun Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Sumatera Utara, Padang Bulan, Medan Baru, Medan, Sumatera Utara 20155, Indonesia
  • Effendy De Lux Putra Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Sumatera Utara, Padang Bulan, Medan Baru, Medan, Sumatera Utara 20155, Indonesia
  • Nerdy Nerdy Department of Pharmacy, Faculty of Pharmacy, Institut Kesehatan Deli Husada Deli Tua, Deli Tua Timur, Deli Tua, Deli Serdang, Sumatera Utara, 20355, Indonesia



Antiaging, Gel, Extract, Peel, Passion Fruit


BACKGROUND: Antiaging cosmetics are cosmetics that can prevent or correct the signs of premature aging. Passion fruit (Passiflora sp.) peel is an agricultural waste contains polyphenol compounds and flavonoids which are a source of natural antioxidants to prevent premature aging. The passion fruit peel extract formulated into gel preparations which can increase the economic value of the passion fruit peel waste.

OBJECTIVE: The objective of the study was to test the antiaging activity of gel preparations containing ethanolic extracts of purple, red, and yellow passion fruit on experimental animal skins with several parameters (wrinkle, melanin, pore, moisture, and elasticity).

METHODS: Gel was made by adding passion fruit peel extract with several concentrations (0.05%, 0.10%, 0.15%, 0.20%, and 0.25%) in gel base. The blank used is a gel base without extracts. Measurement of wrinkle, black pigment (melanin), pore size, moisture content, and elasticity was performed using a skin analyzer. The use of gel is done 2 times a day for 28 days.

RESULTS: Gel with purple, red, and yellow passion fruit peel extract can be formulated into gel preparations. The higher concentration of passion fruit peel extract shows a higher antiaging activity. Gel preparations with purple, red, and yellow passion fruit peel extract, respectively, show the recovery of wrinkle 16.16%, 8.73%, and 6.49%; recovery of melanin 20.11%, 10.75%, and 8.06%; recovery of pore 18.78%, 10.15%, and 7.69%; recovery of moisture 32.74%, 17.70%, and 13.04%; and recovery of elasticity 30.08%, 16.13%, and 12.30%.

CONCLUSIONS: The highest antiaging activity was given by gel preparations containing purple passion fruit peel extract and the lowest antiaging activity was given by gel preparations with yellow passion fruit peel extracts.


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How to Cite

Nazliniwaty N, Harun FR, Putra EDL, Nerdy N. Antiaging Activity of Gel Preparation Containing Three Varieties of Passion Fruit Peel Ethanolic Extract. Open Access Maced J Med Sci [Internet]. 2020 Mar. 20 [cited 2024 May 26];8(A):170-4. Available from:

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