Disseminated Melioidosis Presenting with Community-Acquired Pneumonia: A Presentation Not to be Missed – A Case Report
DOI:
https://doi.org/10.3889/oamjms.2020.4199Keywords:
disseminated melioidosis, pneumonia, abscesses, sepsisAbstract
BACKGROUND: Melioidosis commonly presents with pneumonia and is associated with a high mortality rate. This case report discussed a case of confirmed disseminated melioidosis. The case focused on the chronological clinical progressions of melioidosis which initially masqueraded as community-acquired pneumonia (CAP) and subsequently developed into septicemia. This case report aims to create awareness among the primary care doctors working in a potentially endemic area for melioidosis to be vigilant of its non-specific presentation.
CASE REPORT: We report a case of an 80-year-old man who was treated for CAP and presented with unresolved fever and subsequently sepsis. A contrast-enhanced computed tomography showed disseminated lesions of varying sizes in the lungs, liver, spleen, and blood cultures grew Burkholderia pseudomallei. A pigtail drainage catheter was inserted into the liver abscess. In addition, the patient received a 46-day course of intravenous ceftazidime and a 4-month maintenance regime of oral trimethoprim-sulfamethoxazole and oral doxycycline.
CONCLUSION: Completion of antimicrobial treatment resulted in resolution of clinical signs and abscesses on imaging.
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Kingsley PV, Leader M, Nagodawithana NS, Tipre M, Sathiakumar N. Melioidosis in Malaysia: A review of case reports. PLoS Negl Trop Dis. 2016;10(12):0005182. https://doi. org/10.1371/journal.pntd.0005182 PMid:28005910
Cheng AC, Currie BJ. Melioidosis: Epidemiology, pathophysiology, and management. Clin Microbiol Rev. 2005;18(2):383-416. https://doi:10.1128/CMR.18.2.383-416.2005 PMid:15831829
Pagalavan L. Melioidosis: The Johor Bahru experience. Med J Malaysia. 2005;60(5):599-605. PMid:16515111
Alsaif HS, Venkatesh SK. Melioidosis: Spectrum of radiological manifestations. Saudi J Med Med Sci. 2016;4(2):74-8. https:// doi:10.4103/1658-631X.178286 PMid:30787702
Meumann EM, Cheng AC, Ward L, Currie BJ. Clinical features and epidemiology of melioidosis pneumonia: Results from a 21-year study and review of the literature. Clin Infect Dis. 2012;54(3):362-9. https://doi:10.1093/cid/cir808 PMid:22057702
Currie BJ. Melioidosis: An important cause of pneumonia in residents of and travellers returned from endemic regions. Eur Respir J. 2003;22(3):542-50. https://doi:10.1183/09031936.03.0 0006203 PMid:14516149
Nathan S, Chieng S, Kingsley PV, Mohan A, Podin Y, Ooi MH, et al. Melioidosis in Malaysia: Incidence, clinical challenges, and advances in understanding pathogenesis. Trop Med Infect Dis. 2018;3(1):25. http://doi:10.3390/tropicalmed3010025 PMid:30274422.
Karunarathna AK, Mendis SA, Perera WP, Patabendige G, Pallewatte AS, Kulatunga A. A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka. Trop Dis Travel Med Vaccines. 2018;4(1):12. https://doi:10.1186/ s40794-018-0073-5 PMid:30250746.
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Copyright (c) 2020 Shaun Wayn Paul, Khasnur Abd Malek, Alan Basil Peter, Sabrilhakim Sidek (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
http://creativecommons.org/licenses/by-nc/4.0