Subtle Right Ventricular Affection in Patients with Acute Myocardial Infarction, Echocardiographic Assessment

Authors

  • Abdallah Mohamed Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Egypt
  • Shaaban Alramlawy Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Egypt
  • Samir El-Hadidy Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Egypt
  • Mohamed Ibrahiem Affify Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Egypt
  • Waheed Radwan Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Egypt

DOI:

https://doi.org/10.3889/oamjms.2020.4430

Keywords:

ST-elevation myocardial infarction, Right ventricular affection, Tricuspid annular plane systolic excursion, Right heart strain

Abstract

BACKGROUND: The right ventricle (RV) has historically received less attention than its counterpart of the left side of the heart, yet there is a substantial body of evidence showing that RV size and function are perhaps equally important in predicting adverse outcomes in cardiovascular diseases.

AIM: The aim of our work was to evaluate incidence and impact of right ventricular (RV) affection in patients with acute left ventricular myocardial infarction subjected to primary percutaneous coronary intervention (1ry PCI).

METHODS: The study was conducted on 80 patients who had acute left ventricle ST elevated myocardial infarction (LV STEMI) and subjected to 1ry PCI. The study was done in Cairo University, critical care department. All patients were studied within 2 days after 1ry PCI, RV function was assessed by echocardiography through tricuspid annular plane systolic excursion (TAPSE) and speckle tracking echocardiography. We excluded patients with RV infarction, moderate to severe tricuspid regurgitation, pulmonary hypertension, dilated cardiomyopathy, atrial or ventricular septal defect, and patients who had cardiac dysrhythmias.

RESULTS: Out of 80 patients (64 men and 16 women) included in the study, 38 patients (47.5%) had TAPSE <1.7 cm, and 48 patients (60%) had RV longitudinal strain less negative than −19%.There was a statistically significant relationship between RV affection and anterior STEMI, left anterior descending artery as an infarct-related artery, duration of intensive care unit stay, impairment of LV global and regional systolic function, in-hospital complications, and 1-year mortality.

CONCLUSION: RV dysfunction is not uncommon in acute LV STEMI when using the definition of TAPSE <17 cm and RV longitudinal strain less negative than −19%.There was a significant relationship between RV dysfunction and poor outcome in patients with acute LV STEMI.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Elzinga G, Van Grondelle R, Westerhof N, van den Bos GC. Ventricular interference. Am J Physiol 1974;226(4):941-7. https://doi.org/10.1152/ajplegacy.1974.226.4.941 PMid:4823057

Ferlinz J, Gorlin R, Cohn PF, Herman MV. Right ventricular performance in patients with coronary artery disease. Circulation 1975;52(4):608-15. https://doi.org/10.1161/01.cir.52.4.608 PMid:1157272

Kostuk WJ, Kazamias TM, Gander MP, Simon AL, Ross J Jr. Left ventricular size after acute myocardial infarction: Serial changes and their prognostic significance. Circulation 1973;47:1174-9. https://doi.org/10.1161/01.cir.47.6.1174 PMid:4267843

Harrison A, Hatton N, Ryan JJ. The right ventricle under pressure: Evaluating the adaptive and maladaptive changes in the right ventricle in pulmonary arterial hypertension using echocardiography. Pulm Circ 2015;5(1):29-47. https://doi.org/10.1086/679699 PMid:25992269

Iparraguirre HP, Conti C, Grancelli H, Ohman EM, Calandrelli M, Volman S, et al. Prognostic value of clinical markers of reperfusion in patients with acute myocardial infarction treated by thrombolytic therapy. Am Heart J 1997;134(4):631-8. https://doi.org/10.1016/s0002-8703(97)70045-0 PMid:9351729

Tamborini G, Muratori M, Brusoni D, Celeste F, Maffessanti F, Caiani EG, et al. Is right ventricular systolic function reduced after cardiac surgery? A two and three-dimensional echocardiographic study. Eur J Echocardiogr 2009;10:630. https://doi.org/10.1093/ejechocard/jep015 PMid:19252190

Fine NM, Chen L, Bastiansen PM, Frantz RP, Pellikka PA, Oh JK, et al. Outcome prediction by quantitative right ventricular function assessment in 575 subjects evaluated for pulmonary hypertension. Circ Cardiovasc Imaging 2013;6(5):711. https://doi.org/10.1161/circimaging.113.000640 PMid:23811750

Saito K, Okura H, Watanabe N, Hayashida A, Obase K, Imai K, et al. Comprehensive evaluation of left ventricular strain using speckle tracking echocardiography in normal adults: Comparison of three-dimensional and two-dimensional approaches. J Am Soc Echocardiogr 2009;22:1025-30. https://doi.org/10.1016/j.echo.2009.05.021 PMid:19556106

Kjaergaard J, Petersen CL, Kjaer A, Schaadt BK, Oh JK, Hassager C. Evaluation of right ventricular volume and function by 2D and 3D echocardiography compared to MRI. Eur J Echocardiogr 2006;7(6):430-8. https://doi.org/10.1016/j.euje.2005.10.009 PMid:16338173

Chan YH. Biostatistics102: Quantitative data parametric and non-parametric tests. Singapore Med J 2003;44:391-6. PMid:14700417

Gorter TM, Lexis CP, Hummel YM, Lipsic E, Nijveldt R, Willems TP, et al. Right ventricular function after acute myocardial infarction treated with primary percutaneous coronary intervention (from the glycometabolic intervention as adjunct to primary percutaneous coronary intervention in ST-segment elevation myocardial infarction III trial). Am J Cardiol 2016;118(3):338-44. https://doi.org/10.1016/j.amjcard.2016.05.006 PMid:27265672

Shahar K, Darawsha W, Yalonetsky S, Lessick J, Kapeliovich M, Dragu R, et al. Time dependence of the effect of right ventricular dysfunction on clinical outcomes after myocardial infarction: Role of pulmonary hypertension. J Am Heart Assoc 2016;5(7):e003606. https://doi.org/10.1161/jaha.116.003606 PMid:27402233

Alam M, Wardell J, Andersson E, Samad BA, Nordlander R. Right ventricular function in patients with first inferior myocardial infarction: Assessment by tricuspid annular motion and tricuspid annular velocity. Am Heart J 2000;139(4):710-5. https://doi.org/10.1016/s0002-8703(00)90053-x PMid:10740156

Jensen CJ, Jochims M, Hunold P, Sabin GV, Schlosser T, Bruder O. Right ventricular involvement in acute left ventricular myocardial infarction: Prognostic implications of MRI findings. AJR Am J Roentgenol 2010;194(3):592-8. https://doi.org/10.2214/ajr.09.2829 PMid:20173133

Antoni ML, Scherptong RW, Atary JZ, et al. Prognostic value of right ventricular function in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Circ Cardiovasc Imaging 2010;3(3):264-71. https://doi.org/10.1161/circimaging.109.914366 PMid:20190280

Konishi K, Dohi K, Tanimura M, Sato Y, Watanabe K, Sugiura E, et al. Quantifying longitudinal right ventricular dysfunction in patients with old myocardial infarction by using speckle-tracking strain echocardiography. Cardiovasc Ultrasound 2013;11:23. https://doi.org/10.1186/1476-7120-11-23 PMid:23802850

Zornoff LA, Skali H, Pfeffer MA, SuttonMS, Rouleau JL, Lamas GA, et al. Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction. J Am Coll Cardiol 2002;39(9):1450-5. https://doi.org/10.1016/s0735-1097(02)01804-1 PMid:11985906

Kanar BG, Tigen MK, Sunbul M, Cincin A, Atas H, Kepez A, et al. The impact of right ventricular function assessed by 2-dimensional speckle tracking echocardiography on early mortality in patients with inferior myocardial infarction. Clin Cardiol 2018;41(3):413-8. https://doi.org/10.1002/clc.22890 PMid:29577346

Downloads

Published

2020-11-06

How to Cite

1.
Mohamed A, Alramlawy S, El-Hadidy S, Affify MI, Radwan W. Subtle Right Ventricular Affection in Patients with Acute Myocardial Infarction, Echocardiographic Assessment. Open Access Maced J Med Sci [Internet]. 2020 Nov. 6 [cited 2024 Nov. 23];8(B):1212-8. Available from: https://oamjms.eu/index.php/mjms/article/view/4430