Secretory Carcinoma: A Silent Mass Increasing in the Parotid Gland

Cheng-Chieh Lu; Chien-Jui Cheng; Yu-Chien Kao; Mei-Chien  Chen

doi:10.3889/oamjms.2020.4603

Authors

Cheng-Chieh Lu Department of Otolaryngology, Head and Neck Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Chien-Jui Cheng Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Pathology, Taipei Medical University Hospital, Taipei, Taiwan
Yu-Chien Kao Department of Pathology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Mei-Chien Chen Department of Otolaryngology, Head and Neck Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan

DOI:

https://doi.org/10.3889/oamjms.2020.4603

Keywords:

Mammary analogue secretory carcinoma (MASC), Secretory carcinoma, Salivary gland neoplasms, Salivary gland cancer

Abstract

BACKGROUND: Secretory carcinoma (SC) of the salivary gland, also known as mammary analog secretory carcinoma, is a rare tumor in the parotid gland. This kind of tumor is characterized by generally indolent clinical behavior and expression of a break in the ETV6 gene.

CASE REPORT: We present a unique case of secretory carcinoma and show its favorable prognoses.

CONCLUSION: Secretory carcinoma of the salivary gland is a low-grade carcinoma with a favorable prognosis. It has low regional lymph node and distant metastasis potential. Due to the possibility of misdiagnosis, immunohistochemical studies and FISH are suggested. The most effective treatment is complete surgical excision with negative surgical margins.

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