Sunscreen Activities of Bark Artocarpus heterophyllus against Ultraviolet Ray (Sun Protection Factor) in Lotion Formula

Authors

  • Bastian Arifin Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Rosnani Nasution Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Savila Savila Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Rika Ramadani Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Hira Helwati Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Marianne Marianne Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Ulil Amna Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia
  • Nurdin Saidi Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Syiah Kuala, Banda Aceh, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2020.4665

Keywords:

Sunscreen, Artocarpus heterophyllus, Sun protection factor, Lotion

Abstract

Sunscreen lotion is used to prevent the skin from ultraviolet radiation, which can cause various diseases, such as acne, burning, redness, swelling, wrinkling, and skin cancer. Natural sunscreen lotions contain chemical compounds that have relatively long conjugated double bonds or the presence of hydroxyl groups. The result of the maceration of Artocarpus heterophyllus bark produced ethanol and methanol extracts, based on gas chromatography-mass spectrometry characterization, both extracts contained straight and cyclic chain compounds which had conjugated double bonds. The number of double-bonded compounds in ethanol extract is more than in methanol extract. Sun protection factor (SPF) value of ethanol extract lotion formula is greater than SPF value of methanol extract lotion formula, the SPF value ethanol extract lotion formula at concentration 2; 2.5; 5; 7.5; and 12% were consecutive: 29.801 ± 0.224; 32.797 ± 0.161; 33.808 ± 0.165; 34.580 ± 0.295; and 35.015 ± 0.169, (SPF value of negative control: 0.435 ± 0.2839 and positive control, 31 ± 0.0284). SPF value of methanol extract lotion formula for concentration 2; 2.5; 5; 7.5; and 12% was 14.407 ± 0.010; 26.549 ± 0.476; 30.274 ± 0.208; 32.031 ± 0.302; and 31.942 ± 0.324. Each extract SPF value is higher than the SPF value of the lotion formula. The result of testing the physical properties of the lotion formula shows that the lotion type is o/w, the lotion viscosity ranges from 2450 cP to 4780.0 cP meet Standar Nasional Indonesia (SNI) standards. The pH test results ranged from 6.020 to 7.845 meets SNI. The spreading power of the lotion ranges from 4.70 to 6.75 cm. The adhesive strength of the lotion ranges from 16 to 41 s.

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References

King A, Balaji S, Keswani SG. Biology and function of fetal and pediatric skin. Facial Plast Surg Clin North Am. 2013;21(1):1-6. PMid:23369584

Suhartono E, Thalib I, Aflanie I, Noor Z, Idroes R. Study of interaction between cadmium and bovine serum albumin with UV-vis spectrocopy approach. IOP Conf Ser Mater Sci Eng. 2018;350(1):12008. https://doi. org/10.1088/1757-899x/350/1/012008

Suhartono E, Noor Z, Edyson, Budianto WY, Idroes R. Effect of chronic lead exposure on bone using ATR-FTIR spectroscopy. AIP Conf Proc. 2019;2108(1):20025.

Satoh K, Ooe K, Nagayama H, Makimura K. Prototheca cutis sp. nov., a newly discovered pathogen of protothecosis isolated from inflamed human skin. Int J Syst Evol Microbiol. 2010;60(5):1236-40. https://doi.org/10.1099/ijs.0.016402-0 PMid:19666796

Rahmad R, Earlia N, Nabila C, Inayati I, Amin M, Prakoeswa CR, et al. Antibacterial cream formulation of ethanolic Pliek U extracts and ethanolic residue hexane Pliek U extracts against Staphylococcus aureus. IOP Conf Ser Mater Sci Eng. 2019;523:12011. https://doi. org/10.1088/1757-899x/523/1/012011

Polefka TG, Meyer TA, Agin PP, Bianchini RJ. Effects of solar radiation on the skin. J Cosmet Dermatol. 2012;11(2):134-43. h t t p s : / / d o i . o r g / 1 0 . 1111 / j . 1 4 7 3 - 2 1 6 5 . 2 0 1 2 . 0 0 6 1 4 . x PMid:22672278

Silverstein RM, Morrill TC. Spectrometric Identification of Organic Compounds. 5th ed. New York: Wiley; 1991.

Shaw TE, Currie GP, Koudelka CW, Simpson EL. Eczema prevalence in the United States: Data from the 2003 national survey of children’s health. J Invest Dermatol. 2011;131(1):67-73. https://doi.org/10.1038/jid.2010.251 PMid:20739951

Earlia N, Rahmad R, Amin M, Prakoeswa C, Khairan K, Idroes R. The potential effect of fatty acids from Pliek U on epidermal fatty acid binding protein: Chromatography and bioinformatic studies. Sains Malaysiana. 2019;48(5):1019-24. https://doi. org/10.17576/jsm-2019-4805-10

Suhendra R. A Novel Approach to Multi-class Atopic Dermatitis Disease Severity Scoring Using Multi-class SVM. Indonesia: IEEE Cybern; 2019. https://doi.org/10.1109/ cyberneticscom.2019.8875693

Diepgen TL, Brandenburg S, Aberer W, Bauer A, Drexler H, Fartasch M, et al. Skin cancer induced by natural UV-radiation as an occupational disease-requirements for its notification and recognition. J Dtsch Dermatol Ges. 2014;12(12):1102-6. https://doi.org/10.1111/ddg.12537 PMid:25482691

Goswami PK, Samant M, Srivastava R. Natural sunscreen agents: A review. Sch Acad J Pharm. 2013;2(6):458-63.

Paristiowati M, Moersilah M, Stephanie MM, Zulmanelis Z, Idroes R, Puspita RA. Rosa sp and Hibiscus sabdariffa L extract in ethanol fraction as acid base indicator: Application of green chemistry in education. J Phys Conf Ser. 2019;1402(5):55041. https://doi.org/10.1088/1742-6596/1402/5/055041

Nuraskin CA, Marlina, Idroes R, Soraya C, Djufri. Activities inhibition methanol extract Laban Leaf (Vitex pinnata) on growth of Bacteria S. mutans Atcc 31987. IOP Conf Ser Mater Sci Eng. 2019;523:1-5. https://doi.org/10.1088/1757-899x/523/1/012008

Tallei TE, Linelejan YT, Umboh SD, Adam AA, Muslem, Idroes R. Endophytic Bacteria isolated from the leaf of langusei (Ficus minahassae Tesym. and De Vr.) and their antibacterial activities. IOP Conf Ser Mater Sci Eng 2020;796:012047. https://doi. org/10.1088/1757-899x/796/1/012047

Idroes R, Yusuf M, Saiful S, Alatas M, Subhan S, Lala A, et al. Geochemistry exploration and geothermometry application in the North Zone of Seulawah Agam, Aceh Besar district, Indonesia. Energies. 2019;12(23):4442.

Estevam E, Griffin S, Nasim J, Zieliński D, Aszyk J, Osowicka M, et al. Inspired by nature: The use of plant-derived substrate/enzyme combinations to generate antimicrobial activity in situ. Nat Prod Commun. 2015;10(10):1733-8. h t t p s : / / d o i . o r g / 1 0 . 1 1 7 7 / 1 9 3 4 5 7 8 x 1 5 0 1 0 0 1 0 2 5 PMid:26669114

Pratiwi SU, Lagendijk EL, de Weert S, Idroes R, Hertiani T, Van den Hondel C. Effect of Cinnamomum burmannii Nees ex Bl. and massoia aromatica becc. Essential oils on planktonic growth and biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus in vitro. Int J Appl Res Nat Prod. 2015;8(2):1-13. https://doi.org/10.1055/s-0036-1596813

Tallei TE, Pelealu JJ, Pollo HN, Pollo GA, Adam AA, Effendi Y, et al. Ethnobotanical dataset on local edible fruits in North Sulawesi, Indonesia. Data Brief. 2019;27:104681. https://doi.org/10.1016/j.dib.2019.104681 PMid:31720333

Ningsih DS, Idroes R, Bachtiar BM, Khairan. The potential of five therapeutic medicinal herbs for dental treatment : A review. IOP Conf Ser Mater Sci Eng. 2019;523(1):12009. https://doi. org/10.1088/1757-899x/523/1/012009

Earlia N, Muslem, Suhendra R, Amin M, Prakoeswa CR, Khairan, et al. GC/MS analysis of fatty acids on Pliek U oil and its pharmacological study by molecular docking to filaggrin as drug candidate in atopic dermatitis treatment. ScientificWorldJournal. 2019;2019:8605743. https://doi.org/10.1155/2019/8605743 PMid:31780876

Suhartono E, Setiawan B, Santosa PB, Idroes R, Indrawan MS. Estimation of leaf antioxidant activity using image processing. J Phys Conf Ser. 2019;2019:12057. https://doi. org/10.1088/1742-6596/1374/1/012057

Peng SD, Lin LJ, Ouyang LJ, Zhu BQ, Yuan Y, Jing W, et al. Comparative analysis of volatile compounds between jackfruit (Artocarpus heterophyllus L.) peel and its pulp. Adv Mater Res. 2013;2013:1413-8. https://doi.org/10.4028/www.scientific.net/ amr.781-784.1413

Balbach A. In: Missionaria E, editor. As Frutas Na Medicina Natural. Sao Paulo: Vida Plena; 1992.

ICUC. International Centre for Underutilized Crops Report. United Kingdom: ICUC; 2003.

Salguero CP, Herbal AT. Traditional Recipes for Health and Harmony. United Kingdom: Findhorn Press; 2003.

Likhitwitayawuid K, Chaiwiriya S, Sritularak B, Lipipun V. Antiherpetic flavones from the heartwood of Artocarpus gomezianus. Chem Biodivers. 2006;3(10):1138-43. https://doi.org/10.1002/chin.200710218 PMid:17193228

Arung ET, Shimizu K, Kondo R. Inhibitory effect of isoprenoid-substituted flavonoids isolated from Artocarpus heterophyllus on melanin biosynthesis. Planta Med. 2006;72(9):847-50. https://doi.org/10.1055/s-2006-931606 PMid:16732541

Donsing P, Limpeanchob N, Viyoch J. Evaluation of the effect of Thai breadfruit’s heartwood extract on melanogenesis-inhibitory and antioxidation activities. J Cosmet Sci. 2008;59:41-58. https://doi.org/10.1111/j.1468-2494.2008.00446_4.x PMid:18350234

Bonina F, Lanza M, Montenegro L, Puglisi C, Tomaino A, Trombetta D, et al. Flavonoids as potential protective agents against photo-oxidative skin damage. Int J Pharm. 1996;145(1- 2):87-94. https://doi.org/10.1016/s0378-5173(96)04728-x

Kale SS, Rajmane AH, Urunkar VC, Gaikwad MK, Bhandare SB. Formulation and in-vitro evaluation of sun protection factor of methanolic extract of Zanthoxylum rhetsa DC. Sunscreen lotion. Res J Pharmacogn Phytochem. 2011;3(5):206-10.

Amatullah L, Cahyaningrum TN, Fidyaningsih AN. Antioxidants effectivity in skin lotion formulation of mesocarp fruit extract lontar (Borassus Flabellifer) against white rats Wistar male in-situ. JPSCR J Pharm Sci Clin Res. 2017;2(1):25-34. https:// doi.org/10.20961/jpscr.v2i01.5236

Sharma G, Gadiya J, Dhanawat M. A Textbook of Cosmetic Formulations. Rajasthan: Mewar Univ Rajasthan; 2018. p. 901.

Akademi Farmasi Bina Husada Kendari. Formulasi Lotion dan Penentuan Nilai Sun Proctection Factor (SPF) Ekstrak Kulit Buah Naga Super Merah (Hylocereus costaricensis). Kendari: Akademi Farmasi Bina Husada Kendari; 2016. https://doi. org/10.30595/pharmacy.v15i1.2718

Wasitaatmadja SM. Penuntun ilmu kosmetik medik. Jakarta Penerbit Univ Indones. 1997;3:58-9.

Sayre RM, Agin PP, LeVee GJ, Marlowe E. A comparison of in vivo and in vitro testing of sunscreening formulas. Photochem Photobiol. 1979;29(3):559-66. https://doi.org/10.1111/j.1751-1097.1979.tb07090.x PMid:441130

Mansur JD, Mansur MC, Azulay RD. Determination of sun protection on factor by spectrophotometric methods. Bras Dermatol. 1986;61(3):121-4.

Tadros TF. Emulsion formation, stability, and rheology. Emuls Form Stab. 2013;1:1-75.

Purwaningsih S, Salamah E, Budiarti TA. Formulasi skin lotion dengan penambahan karagenan dan antioksidan alami dari rhizophora mucronata lamk. J Akuatika. 2014;5(1):55-62.

Caesar RY, Hapsari I, Dhiani BA. Formulasi dan aktivitas antibakteri lotion minyak atsiri buah adas (Foeniculum vulgare mill). Media Farm. 2015;11(1):41-54.

Harborne AJ. Phytochemical Methods a Guide to Modern Techniques of Plant Analysis. Berlin, Germany: Springer Science and Business Media; 1998.

Jagtap UB, Panaskar SN, Bapat VA. Evaluation of antioxidant capacity and phenol content in jackfruit (Artocarpus heterophyllus Lam.) fruit pulp. Plant foods Hum Nutr. 2010;65(2):99-104. https://doi.org/10.1007/s11130-010-0155-7 PMid:20198442

Wood C, Murphy E. Sunscreen Efficacy. Glob Cosmet Ind. 2000;167(2):38-43.

Wolf R, Morganti P, Ruocco V. Sunscreens. Clin Dermatol. 1996;19(4):452-9. PMid:11535388

SNI. Sediaan Tabir Surya. Jakarta: SNI; 1996. p. 16.

Zulkarnain AK, Susanti M, Lathifa AN. The physical stability of lotion o/w and w/o from phaleria macrocarpa fruit extract as sunscreen and primary irritation test on rabbit. Maj Obat Tradis. 2013;18(3):141-50.

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Published

2020-07-25

How to Cite

1.
Arifin B, Nasution R, Savila S, Ramadani R, Helwati H, Marianne M, Amna U, Saidi N. Sunscreen Activities of Bark Artocarpus heterophyllus against Ultraviolet Ray (Sun Protection Factor) in Lotion Formula. Open Access Maced J Med Sci [Internet]. 2020 Jul. 25 [cited 2024 Jul. 3];8(A):461-7. Available from: https://oamjms.eu/index.php/mjms/article/view/4665

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