The Analysis of Binahong Leaves Potential (Anredera cordifolia) as an Alternative Treatment of Anticataractogenesis

Feriyani Feriyani; Darmawi Darmawi; Ummu Balqis; Rodiah Rahmawaty Lubis

doi:10.3889/oamjms.2020.4849

Authors

Feriyani Feriyani Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh, Aceh, Indonesia; Faculty of Medicine Universitas Abulyatama
Darmawi Darmawi Laboratory of Research, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, Indonesia; Laboratory of Microbiology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, Indonesia
Ummu Balqis Laboratory of Pathology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, Indonesia
Rodiah Rahmawaty Lubis Department of Ophthalmology, Faculty of Medicine, Universitas Sumatera Utara, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2020.4849

Keywords:

Binahong leaves, Alternative treatment, Cataractogenesis

Abstract

BACKGROUND: Cataract is a condition where the retina cannot capture images completely and causes blindness due to an imbalance of reactive oxygen species (ROS). These free radicals can be suppressed using antioxidants from several plants, one of which is binahong leaves.

AIM: The purpose of this study is to analyze the potential of binahong leaves as an initial screening that can play a role in inhibiting the process of cataractogenesis.

METHODS: By extracting binahong leaves with 60% ethanol, the extracts were tested for phytochemistry using the X technique and GC–MS using the Perkin-Elmer GC Clarus 500. The experimental process and all laboratory analyses were fully carried out from June to December 2019 at the Laboratory of Food Analysis and Yield Agriculture, Department of Agricultural Product Technology, Syiah Kuala University, Banda Aceh.

RESULTS: Analysis of binahong leaf potential showed that binahong leaves contain flavonoids, steroids, phenols, alcoholics, terpenoids, and saponins. While the GC–MS analysis results showed that binahong leaves are rich in phytol and contain fatty acids.

CONCLUSION: Binahong leaves have the potential to be anticataractogenesis because they contain compounds rich in antioxidants.

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