The Coronavirus Disease-19 Infection and the Oral Mucosa

Pier Carmine  Passarelli; Luigi Santacroce; Antonio  D'Addona; Franklin Garcia-Godoy

doi:10.3889/oamjms.2020.4943

Authors

Pier Carmine Passarelli Department of Head and Neck, Oral Surgery and Implantology Unit, Master Coordinator, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy
Luigi Santacroce Ionian Department, Microbiology and Virology Lab, University Hospital of Bari, Bari, Italy http://orcid.org/0000-0001-5671-8124
Antonio D'Addona Department of Head and Neck, Oral Surgery and Implantology Unit, Institute of Clinical Dentistry, UniversitÃ Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy
Franklin Garcia-Godoy Bioscience Research Center, College of Dentistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA; Senior Clinical Investigator, The Forsyth Center, Cambridge, Massachusetts, USA

DOI:

https://doi.org/10.3889/oamjms.2020.4943

Keywords:

COVID-19,, SARS-CoV2,, dental practice,, coronavirus,, infection prevention

Abstract

BACKGROUND: The current coronavirus disease (COVID-19) pandemics induced a modification of daily life and clinical practice. Health care workers, particularly dentists and dental hygienists, have been obliged to limit their activity and to establish new operative protocols.

AIM: We aimed to discuss an easy protocol for the prevention of cross-infections in dental settings.

METHODS: We revised literature data about COVID-19 and oral health to establish how to work safely with dental patients.

RESULTS AND CONCLUSION: A few papers are currently available about the effective prevention of COVID-19 during dental procedures. Most of the revised articles report a potential strong effectiveness of povidone-iodine and its safety for both patients and dental professionals.

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References

Santacroce L, Charitos IA, Del Prete R. COVID-19 in Italy: An overview from the first case to date. Electron J Gen Med. 2020;17:em235. https://doi.org/10.29333/ejgm/7926 DOI: https://doi.org/10.29333/ejgm/7926

Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline Characteristics and Outcomes of 1591 Patients Ifected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020;323(16):1574-81. https:// doi.org/10.1001/jama.2020.5394 PMid:32250385 DOI: https://doi.org/10.1001/jama.2020.4031

Baymakova M, Popov GT. SARS-CoV-2 infection: A review of part of the international experience. Bulg Med J. 2020;14(1):7-12.

Passarelli PC, Lopez MA, Bonaviri GN, Garcia-Godoy F, D’Addona A. Taste and smell as chemosensory dysfunction in COVID-19 infection. Am J Dent. 2020;33(3):135-7. PMid:32470238.

Dziedzic, A, Wojtyczka, R. The impact of coronavirus infectious disease 19 (COVID-19) on oral health. Oral Dis. 2020;1:1-4. https://doi.org/10.1111/odi.13359 PMid:32304276 DOI: https://doi.org/10.1111/odi.13359

Cazzolla AP, Lovero R, Lo Muzio L, Testa NF, Schirinzi AL, Palmieri G, et al. Taste and smell disorders in COVID-19 patients: Role of Interleukin-6. ACS Chem Neurosci. [published online ahead of print, 2020 Aug 4]. https://doi.org/10.1021/ acschemneuro.0c00447 PMid: 32786309

Verillaud B, Slama D, Ayache D, Herman P, Jourdaine C, Hervé C, et al. Efficacy of local budesonide therapy in the management of persistent hyposmia in COVID-19 patients without signs of severity: A structured summary of a study protocol for a randomised controlled trial. Trials. 2020;21(1):666. https://doi.org/10.1186/s13063-020-04585-8 PMid:32690074 DOI: https://doi.org/10.1186/s13063-020-04585-8

Li J, Zhang C, Wu Z, Wang G, Zhao H. The mechanism and clinical outcome of patients with corona virus disease 2019 whose nucleic acid test has changed from negative to positive, and the therapeutic efficacy of favipiravir: A structured summary of a study protocol for a randomised controlled trial. Trials. 2020;21(1):488. https://doi.org/10.1186/s13063-020-04430-y PMid:32503657 DOI: https://doi.org/10.1186/s13063-020-04430-y

Ong SW, Tan YK, Chia PY, Lee TH, Ng OT, Wong MS, et al. Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA. 2020;323(16):1610-2. https://doi.org/10.1001/jama.2020.3227 PMid:32129805 DOI: https://doi.org/10.1001/jama.2020.3227

Eggers M, Koburger-Janssen T, Eickmann M, Zorn J. In vitro bactericidal and virucidal efficacy of povidone-iodine gargle/ mouthwash against respiratory and oral tract pathogens. Infect Dis Ther. 2018;7(2):249-59. https://doi.org/10.1007/ s40121-018-0200-7 PMid:29633177 DOI: https://doi.org/10.1007/s40121-018-0200-7

Sampson V. Oral hygiene risk factor. Br Dent J. 2020;228:569. https://doi.org/10.1038/s41415-020-1545-3 PMid:32332938 DOI: https://doi.org/10.1038/s41415-020-1545-3

Di Serio F, Lovero R, D’Agostino D, Nisi L, Miragliotta G, ContinoR, et al. Evaluation of procalcitonin, Vitamin D and C-reactive protein levels in septic patients with positive emocoltures. Our preliminary experience. Acta Med Mediterr. 2016;32:1911-4. https://doi.org/10.19193/0393-6384_2016_6_182

Gugnani N, Gugnani S. Safety protocols for dental practices in the COVID-19 era. Evid Based Dent. 2020;21(2):56-7. https:// doi.org/10.1038/s41432-020-0094-6 PMid:32591659 DOI: https://doi.org/10.1038/s41432-020-0094-6

Passarelli PC, Passarelli G, Charitos IA, Rella E, Santacroce L, D’Addona A. COVID-19 and oral diseases: How can we manage hospitalized and quarantined patients while reducing risks? Electron J Gen Med. 2020;17(6):em238. https://doi. org/10.29333/ejgm/7945 DOI: https://doi.org/10.29333/ejgm/7945

Sadeghi AM, Karimzadeh I, Lankarani KB, Banakar M. Pharmacotherapy for reducing saliva and droplet production in airborne procedures may help to decrease the COVID-19 transmission: A hypothesis. Med Hypotheses. 2020;144:109874. https://doi.org/10.1016/j.mehy.2020.109874 PMid:32535455 DOI: https://doi.org/10.1016/j.mehy.2020.109874

Passarelli PC, Rella E, Manicone PF, Garcia-Godoy F, D’Addona A. The impact of the COVID-19 infection in dentistry. Exp Biol Med (Maywood). 2020;245(11):940-4. https://doi. org/10.1177/1535370220928905 PMid: 32436748 DOI: https://doi.org/10.1177/1535370220928905

Alharbi A, Alharbi S, Alqaidi S. Guidelines for dental care provision during the COVID-19 pandemic. Saudi Dent J. 2020;32(4):181-6. https://doi.org/10.1016/j.sdentj.2020.04.001 PMid:32292260 DOI: https://doi.org/10.1016/j.sdentj.2020.04.001

Santacroce L, Bottalico L, Charitos IA. The Impact of COVID19 on Italy: A Lesson for the Future. Int J Occup Environ Med. 2020;11(3):151-2. https://doi.org/10.34172/ijoem.2020.1984 PMid:32225178 DOI: https://doi.org/10.34172/ijoem.2020.1984

Santacroce L. Letter in response to the article “Enhancing immunity in viral infections, with special emphasis on COVID19: A review” (Jayawardena et al.). Diabetes Metab Syndr. 2020;14(5):927. https://doi.org/10.1016/j.dsx.2020.06.009 PMid:32585601 DOI: https://doi.org/10.1016/j.dsx.2020.06.009

Charitos IA, Ballini A, Bottalico L, Cantore S, Passarelli PC, Inchingolo F, et al. Special features of SARS-Cov2 in daily practice. World J Clin Cases 2020;(in press) DOI: https://doi.org/10.12998/wjcc.v8.i18.3920