Relationship between CD14 and IgA Levels with the Early Childhood Caries Event Children Age 3–5 Years

Deli Mona; Gusti Revilla; Yanwirasti Yanwirasti; Nila Kusuma

doi:10.3889/oamjms.2020.4963

Authors

Deli Mona Department of Biomedics, Faculty of Dentistry, Andalas University, Padang, Indonesia
Gusti Revilla Department of Anatomy, Faculty of Medicine, Andalas University, Padang, Indonesia
Yanwirasti Yanwirasti Department of Anatomy, Faculty of Medicine, Andalas University, Padang, Indonesia
Nila Kusuma Department of Biomedics, Faculty of Dentistry, Andalas University, Padang, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2020.4963

Keywords:

Caries, CD14, IgA

Abstract

BACKGROUND: Early childhood caries (ECC) is a problem in the field of dental health that occurs in infants and toddlers around the world.

AIM: This study aims to relationship between CD14 and IgA levels with the ECC event children age 3–5 years.

MATERIALS AND METHODS: This type of research is an observational cross-sectional comparative design between children with caries and non-caries. Samples are children aged 3–5 years with a history of consuming bottle milk. The number of samples was 28 people for each group (caries and non-caries) so that the total sample was 56 people. The CD14 and IgA levels measured using the ELISA method. The statistical test used is an independent t-test. p < 0.05 was said to be statistically significant.

RESULTS: The results showed that the mean of CD14 levels was higher in the group caries than in the non-caries, while IgA levels were higher in the group non-caries than in the caries group.

CONCLUSION: This study concluded that early caries childhood caries event children age 3–5 years increased the levels of IgA and decreased CD14 levels.

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