Obesity in Pregnancy – Implications on Pregnancy Events
DOI:
https://doi.org/10.3889/oamjms.2020.5075Keywords:
pregnancy, overweight, obesity, preterm birth, complicationsAbstract
BACKGROUND: Overweight and obesity are serious health problems in most developed countries. The percentage of young women with excessive weight who get pregnant continues to grow every year. This raises a concern about the risks of the mother and the baby during pregnancy and after birth.
AIM: This study aims to determine health risk for overweight mothers and especially the risk for preterm birth.
MATERIALS AND METHODS: This is a prospective and retrospective study taking place in the outpatient clinic of the University Hospital “Maichin Dom”. Our study included 105 pregnant women with BMI ≥25 kg/m2 as a case group and 91 pregnant women with BMI within normal limits as a control group.
RESULTS: Mean BMI in the case group was 34.79 ± 3.71 kg/m2 and 20.20 ± 2.24 kg/m2 in the control group. Among 105 women in the case group, we registered 24.8% (n = 26) who gave birth before term. Preterm births among 91 women in the control group were registered in 17.6% (n = 16) patients. We found a significant correlation between increased BMI and the risk of increased systolic and diastolic blood pressure. Moreover, we found comorbidities in 43.8% of cases and 24.2% of controls.
CONCLUSION: Maternal overweight and obesity during pregnancy are associated with increased risks of preterm delivery and complications of pregnancy. Extra efforts should be made to help women lose weight before this important period of life.
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Vernini JM, Moreli JB, Magalhães CG, Costa RA, Rudge MV, Calderon IM. Maternal and fetal outcomes in pregnancies complicated by overweight and obesity. Reprod Health. 2016;13(1):100. https://doi.org/10.1186/s12978-016-0206-0 PMid:27567898
Karamisheva V, Ivanov S, Nachev A, Marinov B, Jordanova D, Basheva S. Preterm birth--incidence and etiology. Akush Ginekol (Sofiia). 2013;52 Suppl 2:11-4. PMid:24294755
Hitrova-Nikolova S, Nikolov A, Vakrilova L, Yarakova N, Pramatarova T, Popivanova A, et al. Socio-demographic characteristics and Vitamin D status in women born before 32 weeks’. Akush Ginekol (Sofiia). 2014;53(5):27-34. PMid:25558668
Slack E, Best KE, Rankin J, Heslehurst N. Maternal obesity classes, preterm and post-term birth: A retrospective analysis of 479,864 births in England. BMC Pregnancy Childbirth. 2019;19(1):434. https://doi.org/10.1186/s12884-019-2585-z PMid:31752763
Cnattingius S, Villamor E, Johansson S, Edstedt Bonamy AK, Persson M, Wikstrom AK, et al. Maternal obesity and risk of preterm delivery. JAMA. 2013;309(22):2362-70. https://doi.org/10.1001/jama.2013.6295 PMid:23757084
Johansson S, Villamor E, Altman M, Bonamy AK, Granath F, Cnattingius S. Maternal overweight and obesity in early pregnancy and risk of infant mortality: A population based cohort study in Sweden. BMJ. 2014;349:g6572. https://doi.org/10.1136/bmj.g6572
Liu P, Xu L, Wang Y, Zhang Y, Du Y, Sun Y, et al. Association between perinatal outcomes and maternal pre-pregnancy body mass index. Obes Rev. 2016;17(11):1091-102. https://doi.org/10.1111/obr.12455 PMid:27536879
Karamisheva V, Ivanov S, Nikolov A, Jordanova D, Dimitrov G, Nachev A. Perinatal mortality of IUGR neonates. Akush Ginekol (Sofiia). 2014;53 Suppl 1:13-5. PMid:25510035
Marinov B, Andreeva A, Karamisheva V, Museva A. Preterm birth in Bulgaria--changes in aetiology and incidence in the last decade. Akush Ginekol (Sofiia). 2014;53 Suppl 1:33-9. PMid:25510040
Mariona FG. Perspectives in obesity and pregnancy. Womens Health (Lond). 2016;12(6):523-32. PMid:29334009
Stubert J, Reister F, Hartmann S, Janni W. The risks associated with obesity in pregnancy. Dtsch Arztebl Int. 2018;115(16):276-83. https://doi.org/10.3238/arztebl.2018.0276 PMid:29739495
Josefson JL, Feinglass J, Rademaker AW, Metzger BE, Zeiss DM, Price HE, et al. Maternal obesity and Vitamin D sufficiency are associated with cord blood Vitamin D insufficiency. J Clin Endocrinol Metab. 2013;98(1):114-9. https://doi.org/10.1210/jc.2012-2882 PMid:23144468
Papachatzi E, Paparrodopoulos S, Papadopoulos V, Dimitriou G, Vantarakis A. Pre-pregnancy maternal obesity in Greece: A case-control analysis. Early Hum Dev. 2016;93:57- 61. https://doi.org/10.1016/j.earlhumdev.2015.12.006 PMid:26802788
Howell KR, Powell TL. Effects of maternal obesity on placental function and fetal development. Reproduction. 2017;153(3):R97- 108. https://doi.org/10.1530/rep-16-0495 PMid:27864335
Yankova Y, Nikolov A, Nashar S, Vakrilova L. CRIB II score and method of delivery for very low and extremely low birth weight infants. Akush Ginekol (Sofiia). 2012;51(3):3-8. PMid:23236658
Hitrova-Nikolova S, Karamisheva V, Slancheva B. The newborn infant by caesarean section. Akush Ginekol (Sofiia). 2020;59(1):32-7.
Karamisheva V, Ivanov S, Nikolov A, Jordanova D, Dimitrov G, Nachev A. Identification the risk of preterm labor: The role of fetal fibronectin. Akush Ginekol (Sofiia). 2015;54(1):3-6. PMid:25909122
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Copyright (c) 2020 Lilia Koleva, Victoria Spasova, Marieta Popova, Valentina Petkova, Milen Dimitrov (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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