Effect of 0.2% Hyaluronic Acid Gel Topical Application on Healing Period of Oroantral Fistula Treated with Buccal Flap

Authors

  • Nawres Bahaa Mohammed Department of Oral and Maxillofacial Surgery, University of Al Ameed, Kerbala, Iraq
  • Malath Azeez Alsaadi Department of Pharmacology and Toxicology, College of Dentistry, University of Babylon, Hillah, Iraq
  • Safaa Sahib Naji Sultan Department of Surgery, College of Medicine, University of Babylon, Hillah, Iraq
  • Adil Aliakbar Department of Surgery, College of Medicine, University of Babylon, Babil, Iraq

DOI:

https://doi.org/10.3889/oamjms.2020.5157

Keywords:

Buccal flap, Hyaluronic acid, Healing, Oroantral fistula

Abstract

BACKGROUND: Oroantral fistula (OAF) is a pathological communication between maxillary sinus and oral cavity, which treated by various surgical methods including buccal flap and associated with post-operative discomfort and relatively long healing period.

AIM: The objective of the study was to evaluate the effect of 0.2% hyaluronic acid (HA) gel on the healing period after surgical buccal flap treatment of OAF.

METHODS: The records of 20 patients of both genders included and reviewed retrospectively. Ten patients treated with topical 0.2% HA gel while the other 10 patients treated without it. Patients healing process followed up for suture removal appointment.

RESULTS: Statistically significant p ≤ 0.05 decreases in healing period when we compare patients treated with topical HA gel and those without topical HA gel.

CONCLUSION: The use of topical HA gel may have advantages for soft-tissue healing and decrease healing period for patients has OAF treated with surgical buccal flap.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Yilmaz T, Suslu AE, Gursel B. Treatment of oroantral fistula: Experience with 27 cases. Am J Otolaryngol. 2003;24(4):221-3. PMid:12884211

Güven O. A clinical study on oroantral fistulae. J Craniomaxillofac Surg. 1998;26(4):267-71. PMid:9777507

Haas R, Watzak G, Baron M, Tepper G, Mailath G, Watzek G. A preliminary study of monocortical bone grafts for oroantral fistula closure. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96(3):263-6. https://doi.org/10.1016/ s1079-2104(03)00375-5 PMid:12973280

Hernando J, Gallego L, Junquera L, Villarreal P. Oroantral communications. A retrospective analysis. Med Oral Patol Oral Cir Bucal. 2010;15(3):499-03. https://doi.org/10.4317/ medoral.15.e499 PMid:20038901

Dym H, Wolf JC. Oroantral communication. Oral Maxillofac Surg Clin North Am. 2012;24(2):239-47. PMid:22503070

Peñarrocha-Diago M, García B, Gomez D, Balaguer J. Zygomatic bone graft for oral-antral communication closure and implant placement. J Oral Implantol. 2007;33(5):305-9. https:// doi.org/10.1563/1548-1336(2007)33[305:zbgfoc]2.0.co;2 PMid:17987864

Assad M, Bitar W, Alhajj MN. Closure of oroantral communication using platelet-rich fibrin: A report of two cases. Ann Maxillofac Surg. 2017;7(1):117-9. PMid:28713748

Ogunsalu C. A new surgical management for oro-antral communication the resorbable guided tissue regeneration membrane-bone substitute sandwich technique. West Indian Med J. 2005;54(4):261. https://doi.org/10.1590/ s0043-31442005000400011 PMid:16312195

Parvini P, Obreja K, Sader R, Becker J, Schwarz F, Salti L. Surgical options in oroantral fistula management: A narrative review. Int J Implant Dent. 2018;4(1):40. https://doi.org/10.1186/ s40729-018-0152-4 PMid:30588578

Annaqiyah WK, Widiyanti P, Zaidan AH. Hyaluronic acid (HA)- methylcellulose (MC)-based hydrogel with antibacterial AgNPs as a post-surgery intraperitoneal anti-adhesive physical barrier. J Int Dent Med Res. 2018;11(3):1110-15.

Noble PW. Hyaluronan and its catabolic products in tissue injury and repair. Matrix Biol. 2002;21(1):25-9. https://doi.org/10.1016/ s0945-053x(01)00184-6 PMid:11827789

Prosdocimi M, Bevilacqua C. Exogenous hyaluronic acid and wound healing: An updated vision. Panminerva Med. 2012;54(2):129-35. PMid:22525567

Mesa FL, Aneiros J, Cabrera A, Bravo M, Caballero T, Revelles F, et al. Antiproliferative effect of topic hyaluronic acid gel. Study in gingival biopsies of patients with periodontal disease. Histol Histopathol. 2002;17(3):747-53. PMid:12168783

Koray M, Ofluoglu D, Onal EA, Ozgul M, Ersev H, Yaltirik M, et al. Efficacy of hyaluronic acid spray on swelling, pain, and trismus after surgical extraction of impacted mandibular third molars. Int J Oral Maxillofac Surg. 2014;43(11):1399-403. https://doi.org/10.1016/j.ijom.2014.05.003 PMid:24924267

Rehrmann VA. Einemethodezurschliessung von kieferhohlenperforationen. Dtsch Zahnartl Wochenzeitschr. 1936;39:1136.

Khandelwal P, Hajira N. Management of oro-antral communication and fistula: Various surgical options. World J Plast Surg. 2017;6(1):3-8. PMid:28289607

Rodriguez-Merchan EC. Intra articular injections of hyaluronic acid and other drugs in the knee joint. HSS J. 2013;9(2):180-2. https://doi.org/10.1007/s11420-012-9320-x PMid:24426865

Palaia G, Tenore G, Tribolati L, Russo C, Gaimari G, Del Vecchio A, et al. Evaluation of wound healing and postoperative pain after oral mucosa laser biopsy with the aid of compound with chlorhexidine and sodium hyaluronate: A randomized double blind clinical trial. Clin Oral Investig. 2018;30(8):3141- 51. https://doi.org/10.1007/s00784-018-2735-0 PMid:30374831

Lee JH, Jung JY, Bang D. The efficacy of topical 0.2% hyaluronic acid gel on recurrent oral ulcers: Comparison between recurrent aphthous ulcers and the oral ulcers of behçet’s disease. J Eur Acad Dermatol Venereol. 2008;22(5):590-5. https://doi. org/10.1111/j.1468-3083.2007.02564.x PMid:18093111

Romeo U, Libotte F, Palaia G, Galanakis A, Gaimari G, Tenore G, et al. Oral soft tissue wound healing after laser surgery with or without a pool of amino acids and sodium hyaluronate: A randomized clinical study. Photomed Laser Surg. 2014;32(1):10-6. https://doi.org/10.1089/pho.2013.3509 PMid:24328847

Galli F, Zuffetti F, Capelli M, Fumagalli L, Parenti A, Testori T, et al. Hyaluronic acid to improve healing of surgical incisions in the oral cavity: A pilot multicentre placebo-controlled randomised clinical trial. Eur J Oral Implantol. 2008;1(3):199-206. PMid:20467622

Rodanant P, Wattanajitseree K, Shrestha B, Wongsirichat N. Pain and quality of life related to suture removal after 3 or 7 days at the extraction sites of impacted lower third molars. J Dent Anesth Pain Med. 2016;16(2):131-6. https://doi.org/10.17245/ jdapm.2016.16.2.131 PMid:28879306

Downloads

Published

2020-10-05

How to Cite

1.
Mohammed NB, Alsaadi MA, Sultan SSN, Aliakbar A. Effect of 0.2% Hyaluronic Acid Gel Topical Application on Healing Period of Oroantral Fistula Treated with Buccal Flap. Open Access Maced J Med Sci [Internet]. 2020 Oct. 5 [cited 2024 Apr. 18];8(D):194-7. Available from: https://oamjms.eu/index.php/mjms/article/view/5157