The Relation between Lipid Profile and Glycemic Control in Type 2 Diabetes Mellitus Patients in North Sumatera, Indonesia

Rusdiana  Rusdiana; Sry Suryani Widjaja; Maya Savira

doi:10.3889/oamjms.2020.5174

Authors

Rusdiana Rusdiana Department of Biochemistry, Faculty of Medical, Universitas Sumatera Utara, Jl. dr. Mansur Kampus USU Medan 20155, Indonesia http://orcid.org/0000-0002-7308-9291
Sry Suryani Widjaja Department of Biochemistry, Faculty of Medical, Universitas Sumatera Utara, Jl. dr. Mansur Kampus USU Medan 20155, Indonesia
Maya Savira Department of Physiology, Faculty of Medical, Universitas Sumatera Utara, Jl. dr. Mansur Kampus USU Medan 20155, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2020.5174

Keywords:

Diabetes Mellitus type 2, blood sugar levels, Hba1c, Lipid profile

Abstract

BACKGROUND: The global prevalence of type 2 diabetes mellitus (DM), a chronic metabolic disorder, has been steadily increasing. Increasing blood sugar levels (BSL) are reliably measured by glycated hemoglobin (HbA1c).

AIM: The aim of this research is to observe the relation between lipid profile with glycemic control at uncontrolled and controlled type 2 DM, early detection of abnormalities in the lipid profile can minimize cardiovascular complication risk in patients with type 2 DM.

METHODS: Collecting medical data record, for example, blood pressure, height and body mass index, duration of disease, family history, and medicine treatment. Laboratory examination such as BSL, HbA1c levels, and lipid profile such as cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides (TGs) was evaluated. The study was conducted by implementing cross-sectional methods, among 112 patients with type 2 DM who were admitted from various primary health-care centers in Medan city and the surrounding areas in North Sumatera. The sample criteria are type 2 DM’ patients and both genders. The exclusion criteria of the samples are those with type 1 DM and critical disease.

RESULTS: There is a difference between the average lipid profile level (high-density lipoprotein and TG) in controlled and uncontrolled type 2 DM. Furthermore, there is also a difference between the average HbA1c value in controlled type 2 DM and uncontrolled type 2 DM (p<0.005).

CONCLUSION: This study showed a difference in lipid profile (high-density lipoprotein and TG) and HbA1c between uncontrolled and controlled type 2 DM. Therefore, type 2 DM patients were recommended to undergo periodical glycemic and lipid profile examination control to prevent cardiovascular disease complication.

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