Effect of Honey Variation on Blood Glucose Level in Pregnant Wistar Rats (Rattus norvegicus)


  • Syarifuddin Syarifuddin Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
  • Veny Hadju Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
  • Rahayu Inriasari Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia




Moringa, Honey, Body Weight, Pregnant, Wistar Rats


BACKGROUND: In addition to Moringa one of the food products that are often used as supplements is honey. Honey contains carbohydrates and content of antioxidants and other active substances needed during pregnancy.

AIM: This study aimed to look at the effect of the intervention on the blood glucose levels of normal white pregnant Wistar strain of Moringa honey, honey plus Moringa or natural honey interventions.

METHODS: This research method uses a quantitative research with experimental lab research type. With a completely randomized pre-test-post-test controlled completely randomized research design. The samples in this study were 24 white Wistar pregnant rats, divided into four groups, the control group, the honey group, the honey plus Moringa group, and the Moringa honey group, each consisting of six animals. The intervention was carried out for 20 days with initial BB measurements pregnancy (pre) and end of pregnancy (post). Data analysis used paired t-test and one-way ANOVA test.

RESULTS: GD levels showed a significant decrease in GD levels in all groups at the end of pregnancy with a p < 0.05, but a decrease in GD levels between groups did not show a significant difference at the end of the study, the control group (82.33 ± 8.98), honey (83.83 ± 6.67), plus honey (73.17 ± 10.92), and Moringa honey (73.00 ± 6.45) with a p = 0.065 > 0.05.

CONCLUSION: It shows that honey variation has the effect of controlling blood glucose levels during pregnancy.


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How to Cite

Syarifuddin S, Hadju V, Inriasari R. Effect of Honey Variation on Blood Glucose Level in Pregnant Wistar Rats (Rattus norvegicus). Open Access Maced J Med Sci [Internet]. 2020 Sep. 15 [cited 2021 Sep. 20];8(T2):98-103. Available from: https://oamjms.eu/index.php/mjms/article/view/5200