Effect of the Stems Lemongrass (Cymbopogon citratus) in Pallumara and Pepes Anchovy (Stolephorus Sp.) to Uric Acid Levels of Hyperuricemia Elderly Women

Diany Maulid; Burhanuddin Bahar; Saifuddin Sirajuddin; Veni Hadju; Citrakesumasari Citrakesumasari; Masni Masni

doi:10.3889/oamjms.2020.5203

Authors

Diany Maulid Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
Burhanuddin Bahar Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
Saifuddin Sirajuddin Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
Veni Hadju Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
Citrakesumasari Citrakesumasari Department of Nutrition, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
Masni Masni Department of Biostatistics, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2020.5203

Keywords:

Hyperuricemia, Uric Acid Levels, Lemongrass, Pallumara Fish, Pepes Fish

Abstract

BACKGROUND: Compliance with food-base dietary guidelines has been known delivered positive effect on nutrition and public health.

AIM: The aim of the study was to assess the effect of lemongrass stems in pallumara and anchovy pepes on changes in uric acid levels in elderly women in hyperuricemia.

METHODS: This research is a quasi-randomized pre-test-post-test control group design experiment. The study sample was elderly women with hyperuricemia who met the inclusion and exclusion criteria of 45 persons divided into two intervention groups and one control group. The first group was given lemongrass stems in pallumara anchovy, the second group was given lemongrass stems in anchovy pepes, and the control group only consumed family food. Data were analyzed using paired t test, one-way ANOVA, Chi-square, and Kruskal–Wallis.

RESULTS: The results showed that a significant change in uric acid levels in both intervention groups (p = 0.001 < 0.05), whereas the control group was not significant. There was a difference in changes in uric acid levels between the intervention group and the control group (p = 0.000 < 0.05).

CONCLUSION: It was concluded that the large difference in uric acid levels between the intervention group and the control group was 26.5% and 28.3%. It is recommended to use lemongrass in preventing elevated blood uric acid levels.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Andini NK, Nilakusmawati DP, Susilawati M. Faktor-faktor yang mempengaruhi penduduk lanjut usia masih bekerja. J Piramida. 2013;9(1):44-9. https://doi.org/10.21776/ub.jiae.2009.003.02.6

Badan Pusat Statistik. Statistik Penduduk Lanjut Usia 2016. Jakarta: Badan Pusat Statistik; 2018

Kurnia. Solusi Tepat Brantas Asam Urat, Edisi Kedua. Yogyakarta: Cemerlang Publishing; 2009.

Yu Q, Shen H, Hu Y, Chen Y, Tung T. Prevalence and metabolic factors of hyperuricemia in an elderly agricultural and fishing population in Taiwan. J Arch Rheumatol. 2017;32(2):149-57. https://doi.org/10.5606/archrheumatol.2017.6075

Jaliana J, Suhadi S, Sety LO. Faktor-faktor yang berhubungan dengan kejadian asam urat pada usia 20-44 tahun Di RSUD bahteramas provinsi sulawesi tenggara tahun 2017. J Ilmiah Mahasiswa Kesehatan Masyarakat. 2017;3(2):1-13. https://doi.org/10.37887/jimkesmas.v5i1.12361

Boleu FI, Mangimbulude JC, Karwu FF. Hyperurisemia dan hubungan antara asam urat darah dengan gula darah sewaktu dan IMT pada komunitas etnik asli di halmahera utara. J Ilmu Kesehatan Masyarakat. 2018;9(2):96-106. https://doi.org/10.26553/jikm.2018.9.2.96-106

Ewenighi C, Uchechukwu D, Uchechukwu E, Joel O, Linus O, Babatunde A, et al. Prevalence of hyperuricemia and its risk factors in healthy male adults from abakaliki metropolis. Niger J Mol Pathophysiol. 2015;4(3):94-8. https://doi.org/10.5455/jmp.20150915011842

Djafri D, Monalisa FE, Machmud R. Efek modifikasi faktor risiko modifiable penyakit jantung koroner: A hospital-based matched case control study. J Kesehatan Masyarakat Andalas. 2016;11(2):93-9. https://doi.org/10.24893/jkma.11.2.93-99.2017

Lawrence R, Lawrence K, Srivastava R, Gupta D. Antioxidant activity of lemongrass essential oil (Cympopogon citratus) grown in North Indian plains. J Sci Temper. 2015;4:23-9.

Promila P, Madan VK. A review on the phytochemistry and pharmacology of Cymbopogon citratus Stapf (Lemongrass). Pharm Innov J. 2018;7(3):300-4.

Hasim, Falah S, Ayunda RD, Faridah DN. Potential of lemongrass leaves extract (Cymbopogon citratus) as prevention for oil oxidation. J Chem Pharm Res. 2015;7(10):55-60.

Mirghani ME, Liyana Y, Parveen J. Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil. Int Food Res J. 2012;19(2):569-75.

Pelleng MY. Efektivitas Seduhan Herbal Serai (Cymbopogon citratus) Terhadap Kadar Asam Urat Darah Tikus Putih (Rattus norvegicus) Jantan Galur Wistar Yang Diinduksi Streptozotocin (Stz) (Disertasi). Yogyakarta: Politeknik Kesehatan Kementerian Kesehatan; 2019. https://doi.org/10.22219/sm.v9i2.4133

Aryati E, Dharmayanti AW. Manfaat ikan Teri segar (Stolephorus Sp) terhadap pertumbuhan tulang dan gigi. J Odonto Dent. 2014;1(2):52-6. https://doi.org/10.30659/odj.1.2.52-56

Anggriani E, Dewi AP, Novayelinda R. Faktor-faktor yang berhubungan dengan kejadian gout arthritis masyarakat melayu. J Jom Fkp. 2018;5(2):683-92. https://doi.org/10.36729/jam.v4i3.202

Widyanto FW. Artritis gout dan perkembangannya. J Kesehatan. 2014;10(2):145-52. https://doi.org/10.22219/sm.v10i2.4182

Sholihah FM. Diagnosis and treatment gout arthritis. J Majority. 2014;3(7):39-45.

Hastuti VN, Murbawani EA, Wijayanti HS. Hubungan asupan protein total dan protein kedelai terhadap kadar asam urat dalam darah wanita menopause. J Nutr Coll. 2018;7(2):54-60. https://doi.org/10.14710/jnc.v7i2.20823

Boukhatem MN, Ferhat MA, Kameli A, Saidi F, Kebir HT. Lemongrass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan J Med. 2014;9(1):25-31. https://doi.org/10.3402/ljm.v9.25431

Jumepaeng T, Prachakool S, Luthria DL, Chanthai S. Determination of antioxidant capacity and α-amylase inhibitory activity of the essential oils from citronella grass and lemongrass. Int Food Res J. 2013;20(1):481-5.

Shah G, Shri R, Panchal V, Sharma N, Singh B, Mann AS. Scientific basis for the therapeutic use of Cymbopogon citratus, Stapf (Lemongrass). J Adv Pharm Technol Res. 2011;2(1):3-8. https://doi.org/10.4103/2231-4040.79796

Sari DM, Lestarisa T, Alexandra FD, Jelita H, Thalib I. Antioxidant and anti-glycation activity of ethanol lemongrass (Cymbopogon citratus) leaves extract. Int J Pharmacogn Phytochem Res. 2017;9(5):710-715. https://doi.org/10.25258/phyto.v9i5.8153

Olorunnisola SK, Asiyanbi HT, Hammed AM, Simsek S. Biological properties of lemongrass. Int Food Res J. 2013;21(2):455-62.

Anggraeni NI, Hidayat IW, Rachman SD, Ersanda. Bioactivity of Essential Oil from Lemongrass (Cymbopogon citratus Stapf) as Antioxidant Agent. In: AIP Conference Proceedings; 2018 Feb 09. Jakarta: AIP Publishing; 2018. https://doi.org/10.1063/1.5021200

Miean KH, Mohamed S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J Agric Food Chem. 2000;49(6):3106-12. https://doi. org/10.1021/jf000892m

Sukriti D, Munda S, Lal M, Bhattacharyya PR. A short review on chemical composition therapeutic use and enzyme inhibition activities of Cymbopogon species. Indian J Sci Technol. 2016;9(46):1-9. https://doi.org/10.17485/ijst/2016/v9i46/87046

Nijveldt RJ, Nood E, Hoorn DE, Boelens PG, Norren K, Leeuwen PA. Flavonoids: A review of probable mechanisms of action and potential applications. Am J Clin Nutr. 2001;74(4):418-25. https://doi.org/10.1093/ajcn/74.4.418 PMid:11566638

Wulandari S, Subandi, Muntholib D. Inhibisi Xantin Oksidase Oleh Ekstrak Etanol Kulit Melinjo (Gnetum gnemon) Relatif Terhadap Allopurinol (Skripsi). Malang: Universitas Negeri Malang; 2013.

Setianingrum PD, Kusumaningrum ID, Rini DK. Pemberian air rebusan daun salam (Syzygium polyanthum) terhadap penurunan kadar asam urat pada penderita asam urat di dusun kadisoro desa gilangharjo Kecamatan Pandak Kabupaten Bantul DIY tahun 2017. J Kesehatan Ed Khusus. 2019;1:12-23. https://doi.org/10.22216/jit.2018.v12i3.430

Mallongi A, Syamsuar S, Natsir MF, Astuti RD, Rauf AU, Rachmat M, Muhithd A. Potential ecological risks of mercury contamination along communities area in tonasa cement industry Pangkep, Indonesia. Enferm Clín. 2020;30(4):119-22. https://doi.org/10.1016/j.enfcli.2019.10.054

Mallongi A, Limbong E, Naiem F, Ishak H, Basri S, Saleh M, et al. Health risk analysis of exposure to mercury (Hg) and cyanide (CN) in Kayeli village communities Teluk Kayeli district Buru regency. Enferm Clín. 2020;30(4):427-30. https://doi.org/10.1016/j.enfcli.2020.03.007

Aprilita R, Rahayu ST, Syachfitri RD. Uji aktivitas penghambatan xantin oksidase secara in-vitro Oleh Isolat 6,4’-dihidroksi-4- metoksibenzofenon-2-O-Β-D glukopiranosida (C20H22O10) yang diisolasi dari mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl). J Pharm Sci Res. 2016;3(1):1-11. https://doi.org/10.7454/psr.v3i1.3213