Association of Gender, Triglyceride/HDL Ratio, and Physical Activity of Obese Adolescents in Makassar
DOI:
https://doi.org/10.3889/oamjms.2020.5229Keywords:
Gender, Adolescents, Obesity, Triglyceride/HDL RatioAbstract
BACKGROUND: Obesity may cause the increase of triglyceride and decrease of high-density lipoprotein (HDL) levels. Triglyceride/HDL ratio is associated with metabolic disorders. Physical activity is one of the important aspects in preventing obesity. Gender is known to have a relationship with these factors, but it has been inconsistent.
AIM: This study aimed to evaluate the relationship between sex and triglycerides, levels of HDL, triglycerides/HDL ratio, and physical activity of obese adolescents in Makassar.
METHODS: This study used a cross-sectional design involving 93 samples of obese adolescents from three high schools. Measurement of triglyceride and HDL levels was performed by the Prodia laboratory, while physical activity was measured using the International Physical Activity Questioner. Data analysis was performed with Chi-square and Fisher’s exact tests.
RESULTS: The results showed that there is a relationship between gender and triglyceride levels (p = 0.006) and HDL (p = 0.034), but no relationship between the ratio of TG/HDL (p = 0.109) and physical activity was found (p = 0.339).
CONCLUSION: Efforts should be made to reduce the level of risk adolescent obesity on the risk of metabolic syndrome and cardiovascular disease, including increase physical activity. Physical activity is important to maintain the physical and mental of obese adolescents.
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Mahfouz AA, Shatoor AS, Khan MY, Daffalla AA, Mostafa OA, Hassanein MA. Nutrition, physical activity, and gender risks for adolescent obesity in Southwestern Saudi Arabia. Saudi J Gastroenterol. 2011;17(5):318-22. https://doi. org/10.4103/1319-3767.84486 PMid:21912058
Hussain Z, Mehmood S, Hussain B, Ali I, Afzal S. Prevalence of obesity on gender base at Gilgit City Pakistan. Adv Obes Weight Manag Control. 2017;6(2):59-62. https://doi.org/10.15406/ aowmc.2017.06.00149
Negash S, Agyemang C, Matsha TE, Peer N, Erasmus RT, Kengne AP. Differential prevalence and associations of overweight and obesity by gender and population group among school learners in South Africa: A cross-sectional study. BMC Obes. 2017;4:29. https://doi.org/10.1186/s40608-017-0165-1 PMid:28725448
Lissau I. Body mass index and overweight in adolescents in 13 European Countries, Israel, and the United States. Arch Padiatr Adolesc Med. 2004;158(1):27-33. https://doi.org/10.1001/ archpedi.158.1.27 PMid:14706954
Lobstein T, Frelut ML. Prevalence of overweight among children in Europe. Obes Rev. 2003;4(4):195-200. https://doi. org/10.1046/j.1467-789x.2003.00116.x PMid:14649370
Nieves DJ, Cnop M, Retzlaff B, Walden CE, Brunzell JD, Knopp RH, et al. The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-abdominal fat. Diabetes. 2003;52(1):172-9. https://doi. org/10.2337/diabetes.52.1.172 PMid:12502509
Jafar N, Kurniati Y, Indriasari R, Syam A, Arviani A, Patintingan M. Analysis of triglyceride and high-density lipoprotein levels in overweight adolescents. Pak J Nutr. 2019;18(8):778-82. https:// doi.org/10.3923/pjn.2019.778.782
Sinsanta S, Halim SL, Iskandar I. Correlation of body mass index and blood triglyceride levels of UKRIDA medical faculty students for the 2004/2005 academic year. Med Med J. 2006;14(38):1-8. https://doi.org/10.36452/jkdoktmeditek.v14i38.178.
Sinaga I, Tobing CJ, Ardinata D. Description of triglyceride levels in obese adults in pasar II Tanjung Suri Medan. J Methodist Med. 2018;11(2):215-8.
Nguyen D, Kit B, Carrol M. Abnormal cholesterol among children and adolescents in the United States, 2011-2014. NCHS Data Brief. 2015;228:1-8. PMid:26727279
Aranmolate A. Comparison of abnormal cholesterol in children, adolescent and adults in the United States, 2011-2014: Review. Eur J Environ Public Health. 2017;1(1):1-8. https://doi. org/10.20897/ejeph/75156
Shah AS, Heink A, Sexmith H, Dolan L, Gordon S, Khoury J, et al. Obesity drives the decline in large HDL subspecies among male adolescent. Arterioscler Thromb Vasc Biol. 2017;37(1):A220.
Dobiásová M, Frohlich J. The plasma parameter log (TG/ HDL-C) as an atherogenic index: Correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER(HDL)). Clin Biochem. 2001;34:583-8. https://doi. org/10.1016/s0009-9120(01)00263-6 PMid:11738396
Yeom H, Kim HC, Lee JM, Jeon Y, Suh I. Triglyceride to high density lipoprotein cholesterol ratio among adolescents is associated with adult hypertension: The Kangwha study. Lipids Health Dis. 2018;17:212. https://doi.org/10.1186/ s12944-018-0861-y PMid:30200983
Mustelin L, Silventoinen K, Pietiläinen K, Rissanen A, Kaprio J. Physical activity reduces the influence of genetic effects on BMI and waist circumference: A study in young adult twins. Int J Obes (Lond). 2009;33(1):29-36. https://doi.org/10.1038/ijo.2008.258 PMid:19048013
Hills AP, King NA, Armstrong TP. The contribution of physical activity and sedentary behaviours to the growth and development of children and adolescents: Implications for overweight and obesity. Sport Med. 2007;37(6):533-45. https:// doi.org/10.2165/00007256-200737060-00006 PMid:17503878
Caglar E, Aşçı FH. Gender and physical activity level differences in physical self-perception of university students: A case of Turkey. Int J Sport Psychol. 2006;37:58-74.
Santos P, Guerra S, Ribeiro JC, Duarte JA, Mota J. Age and gender-related physical activity. A descriptive study in children using accelerometry. J Sports Med Phys Fitness. 2003;43(1):85-9.
Raskind I, Patil SS, Cunningham SA, Kramer MR. Physical activity patterns among Indian adolescent: Independent and join association of gender and socioeconomic status. Circulation. 2019;139(Suppl 1):322. https://doi.org/10.1161/circ.139. suppl_1.p322
Pacifico L, Bonci E, Andreoli G, Romaggioli S, Di Miscio R, Lombardo CV, et al. Association of serum triglyceride-to-HDL cholesterol ratio with carotid artery intima-media thickness, insulin resistance and nonalcoholic fatty liver disease in children and adolescents. Nutr Metab Cardiovasc Dis. 2014;24(7):737- 43. https://doi.org/10.1016/j.numecd.2014.01.010 PMid:24656140
Sung KC, Reaven G, Kim S. Ability of the plasma concentration ratio of triglyceride/high-density lipoprotein cholesterol to identify increased cardio-metabolic risk in an East Asian population. Diabetes Res Clin Pract. 2014;105(1):96-101. https://doi. org/10.1016/j.diabres.2014.04.021
Kim HJ, Park HA, Cho YG. Gender difference in the level of HDL cholesterol in Korean adult. Korean J Fam Med. 2011;32(3):173- 81. https://doi.org/10.4082/kjfm.2011.32.3.173
Mascitelli L, Pezzetta F. High-density lipoprotein cholesterol and sex difference in coronary heart disease risk. Am J Med. 2006;119(5):e17. https://doi.org/10.1016/j.amjmed.2005.10.044
Rossouw JE. Hormones, genetic factors, and gender differences in cardiovascular disease. Cardiovasc Res. 2002;53(3):550-7. https://doi.org/10.1016/s0008-6363(01)00478-3
Turek LV. Gender-dependent association of HSD11B1 single nucleotide polymorphisms with glucose and HDL-C levels. Genet Mol Biol. 2014;37(3):490-5. https://doi.org/10.1590/ s1415-47572014000400003
Le-Ha C, Beilin LJ, Burrows S, Huang RC, Oddy WH, Hands B, et al. Gender difference in the relationship between passive smoking exposure and HDL-cholesterol levels in late adolescence. J Clin Endocrinol Metab. 2013;98(5):2126-35. https://doi.org/10.1210/jc.2013-1016
Peterson LR, Soto PF, Herrero P, Mohammed BS, Avidan MS, Schechtman KB, et al. Impact of gender on the myocardial metabolic response to obesity. JACC Cardiovasc Imaging. 2008;1(4):424-33. https://doi.org/10.1016/j.jcmg.2008.05.004 PMid:19356462
Mahbuba S, Mohsin F, Rahat F, Nahar J, Begum T, Nahar N. Descriptive epidemiology of metabolic syndrome among obese adolescent population. Diabetes Metab Syndr Clin Res Rev. 2018;12(3):369-74. https://doi.org/10.1016/j.dsx.2017.12.026
He F, Rodriguez-Colon S, Fernandez-Mendoza J, Vgontzas AN, Bixler EO, Berg A, et al. Abdominal obesity and metabolic syndrome burden in adolescents--Penn State children cohort study. J Clin Densitom. 2015;18(1):30-6. https://doi. org/10.1016/j.jocd.2014.07.009 PMid:25220887
Wu H, Xiong L, Xu Q, Wu J, Huang R, Guo Q, et al. Higher serum triglyceride to high-density lipoprotein cholesterol ratio was associated with increased cardiovascular mortality in female patients on peritoneal dialysis. Nutr Metab Cardiovasc Dis. 2015;25(8):749-55. https://doi.org/10.1016/j. numecd.2015.05.006
Quijada Z, Paoli M, Zerpa Y, Camacho N, Cichetti R, Villarroel V, et al. The triglyceride/HDL-cholesterol ratio as a marker of cardiovascular risk in obese children; association with traditional and emergent risk factors. Pediatr Diabetes. 2008;9(5):464-71. https://doi.org/10.1111/j.1399-5448.2008.00406.x PMid:18507788
Gasevic D, Frohlich J, Mancini GJ, Lear SA. Clinical uselfulness of lipid ratios to identify men and women with metabolic syndrome: A cross-sectional study. Lipids Health Dis. 2014;13:159. https://doi.org/10.1186/1476-511x-13-159 PMid:25300321
Taber DR, Robinson WR, Bleich SN, Wang YC. Deconstructing race and gender differences in adolescent obesity: Oaxacablinder decomposition. Obesity (Silver Spring). 2016;24(3):719- 26. https://doi.org/10.1002/oby.21369
Halliday A, Kern ML, Turnbull DA. Can physical activity help explain the gender gap in adolescent mental health? A crosssectional exploration. Ment Health Phys Act. 2019;16:8-18. https://doi.org/10.1016/j.mhpa.2019.02.003
Bloetzer C, Bovet P, Suris JC, Simeoni U, Paradis G, Chiolero A. Screening for cardiovascular disease risk factors beginning in childhood. Public Health Rev. 2015;36:9. https://doi.org/10.1186/ s40985-015-0011-2
Chen X, Wang Y. Tracking of blood pressure from childhood to adulthood: A systematic review and meta-regression analysis. Circulation. 2008;117(25):3171-80. https://doi.org/10.1161/ circulationaha.107.730366 PMid:18559702
Woudberg NJ, Goedecke JH, Blackhurst D, Frias M, James R, Opie LH, et al. Association between ethnicity and obesity with high-density lipoprotein (HDL) function and subclass distribution. Lipids Health Dis. 2016;15:92. https://doi.org/10.1186/ s12944-016-0257-9 PMid:27169717
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Copyright (c) 2020 Nurhaedar Jafar, Aminuddin Syam, Yessy Kurniati, Een Kurnaesih, Reza Aril Ahri, Nurlela Jamaluddin (Author)
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