Deep Brain Stimulation Hardware Infections: A Case Series

Authors

  • Hulagu Kaptan Dokuz Eylül University, Department of Neurosurgery, Izmir, Turkey
  • Furkan Yuzbasi Dokuz Eylül University, Department of Neurosurgery, Izmir, Turkey
  • Fatih Özturk Dokuz Eylül University, Department of Plastic Reconstructive and Aesthetic Surgery, Izmir, Turkey
  • Haluk Vayvada Dokuz Eylül University, Department of Neurosurgery, Izmir, Turkey

DOI:

https://doi.org/10.3889/oamjms.2020.5530

Keywords:

dbs, infections, device, surgery, stn

Abstract

BACKGROUND: The device-related infections and erosion of the surgical wound site are special circumstances among complications of deep brain stimulation (DBS).

AIM: We aimed to discuss different aspects of hardware infections and contribute to the literature by presenting our treatment methods on four patients.

MATERIAL AND METHODS: This study was carried out in the Department of Neurosurgery, School of Medicine Hospital, Dokuz Eylul University. Four DBS cases were included in the study, and a retrospective study was performed.

RESULTS: Electrode placement to bilateral subthalamic nuclei was performed due to Parkinson’s Disease to all four patients. One of the patients was undergone surgical wound site revision 6 times and device removal at last due to device-related infection and erosion of the surgical wound site. The second patient was undergone surgical wound site revision for 2 times and device removal at last due to device-related infection and erosion of the surgical wound site. The third patient had a collection subcutaneously, where the pulse generator was placed. The collection was aspirated. The fourth patient was undergone surgical wound site revision and device removal at last due to device-related infection and erosion of the surgical wound site. All four patients were given IV antibiotics.

CONCLUSION: For the treatment of DBS device-related infections, a long-term IV antibiotherapy is a suitable option before the decision of device removal.

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References

Kaptan H, Çakmur R. Technical case report of deep brain stimulation: Is it possible single electrode reach to both of subthalamic nucleus and ventral intermediate nucleus in one stage? Open Access Maced J Med Sci. 2018;6(4):659-62. https://doi.org/10.3889/oamjms.2018 PMid:29731935

Kaptan H, Ekmekci H. Long-term results for single electrodeguided deep brain stimulation used to treat Parkinson’s disease. Arch Neuropsychiatry. 2019;56:1-4. https://doi.org/10.29399/ npa.23090

Abode-Iyamah KO, Chiang HY, Woodroffe RW, Park B, JareczekFJ, Nagahama Y, et al. Deep brain stimulation hardware-related infections: 10-year experience at a single institution. J Neurosurg. 2018;130:1-10. https://doi.org/10.3171/2017.9.jns1780 PMid:29521584

Brandmeir N, Nehrbass E, McInerney J. An analysis of scalp thickness and other novel risk factors for deep brain stimulator infections. Cureus. 2016;8(9):e792. https://doi.org/10.7759/ cureus.792Error! Hyperlink reference not valid. PMid:27774360

Bjerknes S, Skogseid IM, Sæhle T, Dietrichs E, Toft M. Surgical site infections after deep brain stimulation surgery: Frequency, characteristics and management in a 10-year period. PLoS One. 2014;9(8):e105288. https://doi.org/10.1371/journal. pone.0105288Error! Hyperlink reference not valid. PMid:25122445

Chou YC, Lin SZ, Hsieh WA, Lin SH, Lee CC, Hsin YL, et al. Surgical and hardware complications in subthalamic nucleus deep brain stimulation. J Clin Neurosci. 2007;14(7):643-9. https://doi.org/10.1016/j.jocn.2006.02.016 PMid:17532500

Doshi PK. Long-term surgical and hardware-related complications of deep brain stimulation. Stereotact Funct Neurosurg. 2011;89(2):89-95. https://doi.org/10.1159/000323372 PMid:21293168

Constantoyannis C, Berk C, Honey CR, Mendez I, Brownstone RM. Reducing hardware-related complications of deep brain stimulation. Can J Neurol Sci. 2005;32(2):194-200. https://doi.org/10.1017/s0317167100003966 PMid:16018154

Sillay KA, Larson PS, Starr PA. Deep brain stimulator hardwarerelated infections: Incidence and management in a large series. Neurosurgery. 2008;62(2):360-7. PMid:18382313

Tolleson C, Stroh J, Ehrenfeld J, Neimat J, Konrad P, Phibbs F. The factors involved in deep brain stimulation infection: A large case series. Stereotact Funct Neurosurg. 2014;92(4):227-33. https://doi.org/10.1159/000362934 PMid:25096381

Voges J, Waerzeggers Y, Maarouf M, Lehrke R, Koulousakis A, Lenartz D, et al. Deep-brain stimulation: Long-term analysis of complications caused by hardware and surgery experiences from a single centre. J Neurol Neurosurg Psychiatry. 2006;77(7):868-72. https://doi.org/10.1136/jnnp.2005.081232 PMid:16574733

Bhatia S, Zhang K, Oh M, Angle C, Whiting D. Infections and hardware salvage after deep brain stimulation surgery: A single-center study and review of the literature. Stereotact Funct Neurosurg. 2010;88(3):147-55. https://doi. org/10.1159/000303528 PMid:20357522

Boviatsis EJ, Stavrinou LC, Themistocleous M, Kouyialis AT, Sakas DE. Surgical and hardware complications of deep brain stimulation. A seven-year experience and review of the literature. Acta Neurochir (Wien). 2010;152(12):2053-62. https:// doi.org/10.1007/s00701-010-0749- PMid:20658301

Temel Y, Ackermans L, Celik H, Spincemaille GH, van der Linden C, Walenkamp GH, et al. Management of hardware infections following deep brain stimulation. Acta Neurochir (Wein). 2004;146(4):355-61. https://doi.org/10.1007/ s00701-004-0219- PMid:15057529

Gorgulho A, Juillard C, Uslan DZ, Tajik K, Aurasteh P, Behnke E, et al. Infection following deep brain stimulator implantation performed in the conventional versus magnetic resonance imaging-equipped operating room. J Neurosurg. 2009;110(2):239-46. https://doi.org/10.3171/2008.6 PMid:18991495

Fenoy AJ, Simpson RK Jr., Risks of common complications in deep brain stimulation surgery: Management and avoidance. J Neurosurg. 2014;120(1):132-9. https://doi.org/10.3171/2013.10 PMid:24236657

Rodriguez-Oroz M, Obeso JA, Lang AE, Houeto JL, Pollak P, Rehncrona S, et al. Bilateral deep brain stimulation in Parkinson’s disease: A multicentre study with 4 years follow-up. Brain. 2005;128(10):2240-9. https://doi.org/10.1093/brain/ awh571 PMid:15975946

Kim MS, Jeong JS, Ryu HS, Choi SH, Chung SJ. Infection related to deep brain stimulation in patients with Parkinson disease: Clinical characteristics and risk factors. J Neurol Sci. 2017;383:135-41. https://doi.org/10.1016/j.jns.2017.10.031 PMid:29246601

Ying S, Zeng DN, Chi L, Tan Y, Galzote C, Cardona C, et al. The influence of age and gender on skin-associated microbial communities in urban and rural human populations. PloS One. 2015;10(10):e0141842. https://doi.org/10.1371/journal.pone PMid:26510185

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Published

2020-09-15

How to Cite

1.
Kaptan H, Yuzbasi F, Özturk F, Vayvada H. Deep Brain Stimulation Hardware Infections: A Case Series. Open Access Maced J Med Sci [Internet]. 2020 Sep. 15 [cited 2024 Apr. 25];8(C):172-6. Available from: https://oamjms.eu/index.php/mjms/article/view/5530

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Case Report in Surgery

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