Menopause Anxiety and Depression; How Food Can Help?

Suzanne Fouad; Salwa M. El Shebini; Maha Abdel-Moaty; Nihad Hassan Ahmed; Ahmed Mohamed Saied Hussein; Hend Abbas Essa; Salwa T. Tapozada

doi:10.3889/oamjms.2021.5555

Authors

Suzanne Fouad Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt http://orcid.org/0000-0001-9724-6135
Salwa M. El Shebini Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
Maha Abdel-Moaty Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
Nihad Hassan Ahmed Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
Ahmed Mohamed Saied Hussein Department of Food Technology, National Research Centre, Dokki, Giza, Egypt
Hend Abbas Essa Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
Salwa T. Tapozada Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt

DOI:

https://doi.org/10.3889/oamjms.2021.5555

Keywords:

Anxiety, Depression, Fatty acids, Menopause, Phytoestrogen

Abstract

BACKGROUND: Anxiety and depression are reported as two major frequent and chief complaints among peri-menopausal women in several societies.

AIM: The objective of the study was to study the effect of using two dietary supplements to beat depression and anxiety associated with menopause.

SUBJECTS AND METHODS: Sixty-six volunteers’ menopausal women participated on the study for 8 weeks, 35 subjects consumed daily cookies prepared mainly from soya flour and flaxseed, and 31 females consumed daily a blend composed mainly of raw unroasted peanut and raw sesame. Follow-up was performed with menopause rating scale, anxiety score, depression score, and biochemical parameters.

RESULTS: Soya cookies were rich in plant-based protein and total phenols while blend was a good source of unsaturated fatty acid. Blend consumers showed significant percentage reduction in beck anxiety score and beck depression score after intervention, more than cookies consumers group. The anthropometrics parameters were statistical significant changed on both groups, more on the group who consumed the soya cookies. Soya cookies demonstrated an anti-inflammatory effect, while blend had an antioxidant and anti-inflammatory effects as was shown on the serum assay of interleukin-6 and malondialdehyde as an inflammatory marker and an antioxidant marker, respectively.

CONCLUSION: From the results, it can be concluded that the supplementation of products enriched with unsaturated fatty acid was more beneficial to slow down the psychological menopause symptoms than natural estrogen rich product consumption.

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