Menopause Anxiety and Depression; How Food Can Help?


  • Suzanne Fouad Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
  • Salwa M. El Shebini Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
  • Maha Abdel-Moaty Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
  • Nihad Hassan Ahmed Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
  • Ahmed Mohamed Saied Hussein Department of Food Technology, National Research Centre, Dokki, Giza, Egypt
  • Hend Abbas Essa Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt
  • Salwa T. Tapozada Department of Nutrition and Food Science, National Research Centre, Dokki, Giza, Egypt



Anxiety, Depression, Fatty acids, Menopause, Phytoestrogen


BACKGROUND: Anxiety and depression are reported as two major frequent and chief complaints among peri-menopausal women in several societies.

AIM: The objective of the study was to study the effect of using two dietary supplements to beat depression and anxiety associated with menopause.

SUBJECTS AND METHODS: Sixty-six volunteers’ menopausal women participated on the study for 8 weeks, 35 subjects consumed daily cookies prepared mainly from soya flour and flaxseed, and 31 females consumed daily a blend composed mainly of raw unroasted peanut and raw sesame. Follow-up was performed with menopause rating scale, anxiety score, depression score, and biochemical parameters.

RESULTS: Soya cookies were rich in plant-based protein and total phenols while blend was a good source of unsaturated fatty acid. Blend consumers showed significant percentage reduction in beck anxiety score and beck depression score after intervention, more than cookies consumers group. The anthropometrics parameters were statistical significant changed on both groups, more on the group who consumed the soya cookies. Soya cookies demonstrated an anti-inflammatory effect, while blend had an antioxidant and anti-inflammatory effects as was shown on the serum assay of interleukin-6 and malondialdehyde as an inflammatory marker and an antioxidant marker, respectively.

CONCLUSION: From the results, it can be concluded that the supplementation of products enriched with unsaturated fatty acid was more beneficial to slow down the psychological menopause symptoms than natural estrogen rich product consumption.


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How to Cite

Fouad S, El Shebini SM, Abdel-Moaty M, Ahmed NH, Hussein AMS, Essa HA, Tapozada ST. Menopause Anxiety and Depression; How Food Can Help?. Open Access Maced J Med Sci [Internet]. 2021 Jan. 6 [cited 2023 Feb. 4];9(B):64-71. Available from:

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