Effect of Progressive Muscle Relaxation on Sleep Quality and Side Effects of Chemotherapy in Children with Cancer: Randomized Clinical Trial

Authors

  • Erna Sulistyawati Program of Nursing Science, Universitas Muhammadiyah Semarang, Semarang, Indonesia
  • Allenidekania Allenidekania Department of Basic Nursing Science, Faculty of Nursing, Universitas Indonesia, Depok, Indonesia
  • Dewi Gayatri Department of Basic Nursing Science, Faculty of Nursing, Universitas Indonesia, Depok, Indonesia https://orcid.org/0000-0003-1477-0033

DOI:

https://doi.org/10.3889/oamjms.2021.5774

Keywords:

Cancer, Progressive muscle relaxation, Sleep disturbances

Abstract

BACKGROUND: Sleep disturbance affects quality of life in children receiving chemotherapy.

AIM: The aim of this study was to identify the effect of progressive muscle relaxation on the sleep quality and side effects of chemotherapy in children with cancer.

METHODS: This study used randomized clinical trial with single blind method, where 30 children were allocated randomly to the control group and intervention group. The intervention group received progressive muscle relaxation twice a day, in the morning and evening, 15 minutes each session for 7 days. Control group received routine nursing care.

RESULTS: The study concluded there was no significant difference in the two groups on fatigue and pain. However, progressive muscle relaxation had significant relation to decreased sleep quality score.

CONCLUSION: Relaxation therapy, particularly progressive muscle relaxation, may be one of the nursing cares to improve sleep quality and reduce the side effects of chemotherapy in children with cancer.

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References

Kementerian Kesehatan RI. Buku Saku Penemuan Dini Kanker Pada Anak. Jakarta: Direktorat Jenderal Pencegahan dan Pengendalian Penyakit Tidak Menular; 2016. https://doi.org/10.22236/jmbp.v1i1.5708 DOI: https://doi.org/10.22236/jmbp.v1i1.5708

Carman S, Kyle T. Essentials of Pediatric Nursing. 2nd ed. Philadelphia, AP: Lippincott Williams and Wilkins; 2013.

Ball JW, Bindler Ruth C, Cowen Kay J. Principles of Pediatric Nursing: Caring for Children. 5th ed. New Jersey: Pearson Education Inc.; 2012.

Marcdante K, Kliegman RM, Behrman RE. Nelson: Essentials of Pediatric. 6th ed. Philadelphia, PA: Saunders Elsevier; 2014.

National Cancer Institute. Definition of Cancer, a Brief Explanation of the Origins of Cancer in Cells, Basic Cancer Statistics, and Links to other NCI Cancer-related Resources. National Cancer Institute; 2015. Available from: http://www.cancer.gov/about-cancer/what-is-cancer. [Last access on 2017 May 22]. https://doi.org/10.1093/jnci/79.3.610-a DOI: https://doi.org/10.1093/jnci/79.3.610-a

World Health Organization. Global Status Report on Noncommunicable Diseases 2014: Attaining the Nine Global Noncommunicable Diseases Targets; a Shared Responsibility. Geneva: World Health Organization; 2014. Available from: http://www.who.int. [Last access on 2017 Jul 01].

Nicki LP, Barbara LM. Pediatric Nursing: Caring for Children and Their Families. 3th ed. Delmar: Cengage Learning; 2012.

Nancy EK. The Pediatric Chemotherapy and Biotherapy Curriculum. 3rd ed. United States of America: APHON; 2011.

Walter LM, Nixon GM, Davey MJ, Downie PA, Horne RS. Sleep and fatigue in pediatric oncology: A review of the literature. Sleep Med Rev. 2015;24:71-82. https://doi.org/10.1016/j.smrv.2015.01.001 PMid:25679070 DOI: https://doi.org/10.1016/j.smrv.2015.01.001

McCulloch R, Hemsley J, Kelly P. Symptom management during chemotherapy. Pediatr Child Heal. 2013;24(4):166-71. DOI: https://doi.org/10.1016/j.paed.2013.10.007

Erickson JM. Approaches to measure sleep wake disturbances in adolescents with cancer. J Pediatr Nurs. 2009;24(4):255-69. PMid:19632503 DOI: https://doi.org/10.1016/j.pedn.2008.03.004

Kwekkeboom KL, Abbott-Anderson K, Cherwin C, Roiland R, Serlin RC, Ward SE. Pilot randomized controlled trial of a patient-controlled cognitive-behavioral intervention for the pain, fatigue, and sleep disturbance symptom cluster in cancer. J Pain Symptom Manage. 2012;44(6):810-22. https://doi.org/10.1016/j.jpainsymman.2011.12.281 PMid:22771125 DOI: https://doi.org/10.1016/j.jpainsymman.2011.12.281

van Litsenburg RR, Huisman J, Hoogerbrugge PM, Egeler RM, Kaspers GJ, Gemke RJ. Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: An exploratory study. Health Qual Life Outcomes. 2011;9(1):25. https://doi.org/10.1186/1477-7525-9-25 PMid:21496357 DOI: https://doi.org/10.1186/1477-7525-9-25

Buffum D, Koetters T, Cho M, Macera L, Paul SM, West C, et al. The effects of pain, gender, and age on sleep/wake and circadian rhythm parameters in oncology patients at the initiation of radiation therapy. J Pain. 2011;12(3):390-400. https://doi.org/10.1016/j.jpain.2010.09.008 PMid:21146465 DOI: https://doi.org/10.1016/j.jpain.2010.09.008

Walker AJ, Pongsing Y, Nail L, Pedhiwala N, Leo M, Price J, et al. Sleep wake patterns of school-age children and adolescents before diagnosis and during induction chemotherapy for acute lymphocytic leukemia. J Pediatr Nurs. 2011;26(6):e37-44. https://doi.org/10.1016/j.pedn.2011.02.006 PMid:22055382 DOI: https://doi.org/10.1016/j.pedn.2011.02.006

Kaleyias J, Manley P. Sleep disorders in children with cancer. YSPEN. 2012;19(1):25-34. PMid:22641073 DOI: https://doi.org/10.1016/j.spen.2012.02.013

Rahmawaty F, Allenidekania, Waluyanti F. Masalah Tidur dan Kelelahan Pada Remaja Pengidap Kanker Yang Mendapatkan Kemoterapi. Indonesia: Universitas Indonesia; 2013.

Sahin ZA, Dayapoglu N. Effect of progressive relaxation exercises on fatigue and sleep quality in patients with chronic obstructive lung disease (COPD). Complement Ther Clin Pract. 2015;21(4):277-81. https://doi.org/10.1016/j.ctcp.2016.05.013 PMid:26573455 DOI: https://doi.org/10.1016/j.ctcp.2016.05.013

Cohen R, Halevy A, Shuper A. Children’s sleep disturbance scale in differentiating neurological disorders. Pediatr Neurol. 2013;49(6):465-8. https://doi.org/10.1016/j.pediatrneurol.2013.06.010 PMid:24080271 DOI: https://doi.org/10.1016/j.pediatrneurol.2013.06.010

Gapstur R, Gross CR, Ness K. Factors associated with sleep-wake disturbances in child and adult survivors of pediatric brain tumors: A review. Oncol Nurs Forum. 2009;36(6):723-31. https://doi.org/10.1188/09.onf.723-731 PMid:19887361 DOI: https://doi.org/10.1188/09.ONF.723-731

Sadeh A. Cognitive behavioral treatment for childhood sleep disorders. Clin Psychol Rev. 2005;25(5):612-28. PMid:15979219 DOI: https://doi.org/10.1016/j.cpr.2005.04.006

Kanitz JL, Camus ME, Seifert G. Keeping the balance an overview of mind-body therapies in pediatric oncology. Complement Ther Med. 2013;21(Suppl 1):S20-5. https://doi.org/10.1016/j.ctim.2012.02.001 PMid:23578913 DOI: https://doi.org/10.1016/j.ctim.2012.02.001

Srilekha S, Soumendra S, Chattopadhyay PK. Effect of muscle relaxation trainning as a function of improvement in attentiveness in children. Proc Soc Behav Sci. 2013;91:606-13. https://doi.org/10.1016/j.sbspro.2013.08.460 DOI: https://doi.org/10.1016/j.sbspro.2013.08.460

Lee E, Bhattacharya J, Sohn C, Verres R. Monochord sounds and progressive muscle relaxation reduce anxiety and improve relaxation during chemotherapy: A pilot EEG study. Complement Ther Med. 2012;20(6):409-16. https://doi.org/10.1016/j.ctim.2012.07.002 PMid:23131371 DOI: https://doi.org/10.1016/j.ctim.2012.07.002

Charalambous A, Giannakopoulou M, Bozas E, Paikousi L. A randomized controlled trial for the effectiveness of progressive muscle relaxation and guided imagery as anxiety reducing interventions in breast and prostate cancer patients undergoing chemotherapy. Evid Based Complement Alternat Med. 2015;2015:270876. https://doi.org/10.1155/2015/270876 PMid:26347018 DOI: https://doi.org/10.1155/2015/270876

Sastroasmoro S, Ismael S. Dasar-dasar Metodologi Penelitian Klinis. 5th ed. Jakarta: Sagung Seto; 2010.

Dahlan MS. Membaca dan Menelaah Jurnal Uji Klinis. Jakarta: Salemba Medika; 2010.

Sari R. Pengaruh Relaksasi otot Progresif Terhadap Kenyamanan, Mual dan Muntah Akibat Kemoterapi Pada Pasien Kanker Anak di RSUP H. Adam Malik Medan. Indonesia: Universitas Indonesia; 2013. https://doi.org/10.32734/tm.v1i1.33 DOI: https://doi.org/10.32734/tm.v1i1.33

Vallance K, Yang J, Li J, Crabtree VM, Hinds PS, Mandrell BN. Disturbed sleep in pediatric patients with leukemia: The potential role of interleukin-6 (–174GC) and tumor necrosis factor (–308GA) polymorphism. Oncol Nurs Forum. 2011;38(5):E365-72. https://doi.org/10.1188/11.onf.e365-e372 PMid:21875833 DOI: https://doi.org/10.1188/11.ONF.E365-E372

Rosen G, Harris AK, Liu M, Dreyfus J, Krueger J, Messinger YH. The effects of dexamethasone on sleep in young children with acute lymphoblastic leukemia. Sleep Med. 2015;16(4):503-9. https://doi.org/10.1016/j.sleep.2014.11.002 PMid:25799940 DOI: https://doi.org/10.1016/j.sleep.2014.11.002

Daniel LC, Li Y, Kloss JD, Reilly AF, Barakat LP. The impact of dexamethasone and prednisone on sleep in children with acute lymphoblastic leukemia. Support Care Cancer. 2016;24(9):3897-906. https://doi.org/10.1007/s00520-016-3234-y PMid:27108263 DOI: https://doi.org/10.1007/s00520-016-3234-y

Hinds P, Hockenberry M, Srivastava DK, Gattuso J, Jones H, West N, et al. Sleep, fatigue, and dexamethasone in children and adolescents with acute lymphocytic leukemia. Oncol Nurs Forum. 2007;34(1):197-8.

Rogers VE, Ancoli-Israel S, Hinds PS. Impairment in circadian activity rhythms occurs during dexamethasone therapy in children with leukemia. Pediatr Blood Cancer. 2014;61(11):1986-91. https://doi.org/10.1002/pbc.25147 PMid:25066691 DOI: https://doi.org/10.1002/pbc.25147

Combs D, Goodwin JL, Quan SF, Morgan WJ. Longitudinal differences in sleep duration in hispanic and Caucasian children. Sleep Med. 2016;18:61-6. https://doi.org/10.1016/j.sleep.2015.06.008 PMid:26299467 DOI: https://doi.org/10.1016/j.sleep.2015.06.008

Vallance K, Liu W, Mandrell BN, Panetta JC, Gattuso JS, Hockenberry M, et al. Mechanisms of dexamethasone-induced disturbed sleep and fatigue in paediatric patients receiving treatment for ALL. Eur J Cancer. 2010;46(10):1848-55. https://doi.org/10.1016/j.ejca.2010.03.026 PMid:20400291 DOI: https://doi.org/10.1016/j.ejca.2010.03.026

Hockenberry MJ, Hooke MC, Gregurich M, Mccarthy K, Sambuco G, Krull K. Symptom clusters in children and adolescents receiving cisplatin, doxorubicin, or ifosfamide. 2010;37(1):E16-27. https://doi.org/10.1188/10.onf.e16-e27 PMid:20044328 DOI: https://doi.org/10.1188/10.ONF.E16-E27

Wong DL, Hockenberry M, Wilson D, Winkelstein ML, Schwartz P. Buku Ajar Keperawatan Pediatrik. 6th ed. Jakarta: EGC; 2009.

Potter PA, Perry A. Fundamental of Nursing. 7th ed. Singapore: Elsevier; 2010.

Kozier B, Erb G, Berman A, Snyder S. Buku Ajar Fundamental Keperawatan: Konsep, Proses, and Praktik. Jakarta: EGC; 2010.

Zupanec S, Jones H, Mcrae L, Weston J. A sleep hygiene and relaxation intervention for children with acute lymphoblastic leukemia. Cancer Nurs. 2017;40(6):488-96. https://doi.org/10.1097/ncc.0000000000000457 PMid:27922922 DOI: https://doi.org/10.1097/NCC.0000000000000457

Kaushal DB, Narendra BD, Smitha D. A comparative study between relaxation technique and aerobic exercise in fatigue during chemotherapy in acute lymphoblastic leukemia in children. Indian J Physiother Occup Ther. 2013;7(3):140-5. https://doi.org/10.5958/j.0973-5674.7.3.081 DOI: https://doi.org/10.5958/j.0973-5674.7.3.081

Utami A. Faktor-faktor Yang Mempengaruhi Kelelahan Pada Anak Dengan Kanker. Indonesia: Universitas Indonesia; 2016.

Nunes MD, Jacob E, Adlard K, Secola R, Nascimento L. Fatigue and sleep experiences at home in children and adolescents with cancer. Oncol Nurs Forum. 2015;42(5):498-506. https://doi.org/10.1188/15.onf.498-506 PMid:26302278 DOI: https://doi.org/10.1188/15.ONF.498-506

Allenidekania, Sari R. The Effectiveness of Exercise: Progressive Muscle Relaxation (PMR) to Reduce Cancer Related Fatigue in Children Receiving Chemotherapy at RS Adam Malik, Medan. Bali: International Nursing Conference; 2013.

Yeh CH, Chiang YC, Lin L, Yang CP, Chien LC, Weaver MA, et al. Clinical factors associated with fatigue over time in paediatric oncology patients receiving chemotherapy. Br J Cancer. 2008;99(1):23-9. https://doi.org/10.1038/sj.bjc.6604434 PMid:18577992 DOI: https://doi.org/10.1038/sj.bjc.6604434

Duff VG, Lee KA, Nail LM, Nicholson S, Johnson K. Pain, sleepdisturbance, and fatiguein children with leukemia and their parents: A pilot study. Oncol Nurs Forum. 2006;33(3):641-6. PMid:16676020 DOI: https://doi.org/10.1188/06.ONF.641-646

Christaki M, Yfandopoulou P. Progressive muscle relaxation as treatment option for children/adolescents with functional gastrointestinal disorders. Health Sci J. 2014;8:187-92.

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Published

2021-06-26

How to Cite

1.
Sulistyawati E, Allenidekania A, Gayatri D. Effect of Progressive Muscle Relaxation on Sleep Quality and Side Effects of Chemotherapy in Children with Cancer: Randomized Clinical Trial. Open Access Maced J Med Sci [Internet]. 2021 Jun. 26 [cited 2024 Nov. 4];9(T4):300-8. Available from: https://oamjms.eu/index.php/mjms/article/view/5774