Zinc Intake, Zinc Serum Levels, and Intelligence in School Children in Rural Areas

Authors

  • Rostika Flora Study Program of Public Health, Faculty of Public Health, Sriwijaya University, Indonesia https://orcid.org/0000-0002-2904-0407
  • Nur Alam Fajar Study Program of Public Health, Faculty of Public Health, Sriwijaya University, Indonesia
  • Fatmalina Febri Study Program of Nutrition, Faculty of Public Health, Sriwijaya University, Indonesia
  • Indah Yuliana Study Program of Nutrition, Faculty of Public Health, Sriwijaya University, Indonesia
  • Yuliarti Yuliarti Study Program of Nutrition, Faculty of Public Health, Sriwijaya University, Indonesia
  • Nurlaili Nurlaili Study Program of D-III Nursery, Faculty of Mathematics and Science, Bengkulu University, Indonesia
  • Ikhsan Ikhsan Study Program of D-III Nursery, Faculty of Mathematics and Science, Bengkulu University, Indonesia
  • Samwilson Slamet Study Program of D-III Nursery, Faculty of Mathematics and Science, Bengkulu University, Indonesia
  • Risnawati Tanjung Study Program of Environmental Health, Polytechnic of Health of the Ministry of Health, Medan, Indonesia
  • Aguscik Aguscik Study Program of Nursery, Polytechnic of Health of the Ministry of Health, Palembang, Indonesia
  • Yeni Anna Appulembang Study Program of psychology, Faculty of Medicine, Sriwijaya University, Indonesia https://orcid.org/0000-0003-3289-6158
  • Mohammad Zulkarnain Public Health Science, Faculty of Medicine, Sriwijaya University, Indonesia https://orcid.org/0000-0002-0966-5100

DOI:

https://doi.org/10.3889/oamjms.2021.5869

Keywords:

Zinc serum, Zinc intake, Level of intelligence, School children, Rural area

Abstract

BACKGROUND: Children in rural areas are susceptible to zinc deficiency. Zinc deficiency in children can affect cognitive function in children. Zinc plays a role in cellular function and critical brain growth processes, including cell replication, DNA and RNA synthesis, and the release of neurotransmitters.

AIM: This study aimed to analyze the condition of zinc deficiency and its relationship with the level of intelligence in children in rural areas.

METHODS: The study design was cross-sectional, with a sample of 44 elementary school children aged 9–12 years taken randomly. Blood was drawn to measure serum Zn-levels, and serum Zn-levels were measured using Colorimetric Assay Kit (E-BC-K137). Zinc intake data were obtained from the food recall form, which was carried out 3 × 24 h. The level of intelligence is measured by the Culture Fair Intelligence Test method. The sample characteristics data obtained through a questionnaire. Furthermore, the data were analyzed using the Chi-square test.

RESULTS: About 84.2% of children with insufficient zinc intake had low serum Zn-levels. There was a significant relationship between zinc intake and serum zinc levels (p = 0.026; PR = 4.293). Children with low serum zinc levels of 96.5% have intelligence levels below average. There was a significant relationship between serum zinc levels and intelligence level as well (p = 0.001; PR = 24,500).

CONCLUSION: Zinc deficiency in children is characterized by low serum Zn-levels. Low serum Zn-level is caused by low zinc intake, thus children with low serum Zn-levels are at risk of having intelligence level below average. Therefore, health education about the importance of zinc intake in children should be given to parents, so that the incidence of zinc deficiency in children can be reduced.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Dijkhuizen MA, Wieringa FT, West CE, Muherdiyantiningsih, Muhilal. Concurrent micronutrient deficiencies in lactating mothers and their infants in Indonesia. Am J Clin Nutr. 2001;73(4):786-91. PMid:11273854

Herman S. Research Report on Micronutrient Problems in Indonesia, Exceptional Attention to Vitamin A Deficiency (VAD), Anemia, and Zinc. Jakarta: Ministry of Health of the Republic of Indonesia; 2007.

World Health Organization. Malnutrition: The Global Picture. Geneva: World Health Organization; 2004.

International Zinc Nutrition Consultative Group. International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr Bull. 2004;25(1 Suppl 2):S99- 203. https://doi.org/10.1177/156482650402500220 PMid:18046856 DOI: https://doi.org/10.1177/156482650402500220

Khan AA, Bano N, Salam A. Child malnutrition in South Asia: A comparative Perspective. South Asian Surv. 2007;14(1):129-45. https://doi.org/10.1177/097152310701400110 DOI: https://doi.org/10.1177/097152310701400110

Almatrsier S. Prinsip Dasar Ilmu Gizi. Jakarta: PT, Gramedia Pustaka Utama; 2010.

Jagveer C, Rakesh J, Pramod S, Ravinder G, Sushil. A study of iron and zinc deficiency on short term memory in children & effect of their supplementation. Asian J Biomed Pharm Sci. 2015;5:12-5.

Setyaningrum R, Triyanti, Indrawani Y. Learning in early childhood education with cognitive development in children. Natl Public Health J. 2014;8(6):243-24. DOI: https://doi.org/10.21109/kesmas.v0i0.375

Wessells KR, Brown KH. Estimating the global prevalence of zinc deficiency: Results based on zinc availability in national food supplies and the prevalence of stunting. PLoS One. 2012;7(11):e50568. https://doi.org/10.1371/journal.pone.0050568 PMid:23209782 DOI: https://doi.org/10.1371/journal.pone.0050568

Fesharakinia A, Zarban A, Gholam RS. Prevalence of zinc deficiency in elementary school children of South Khorasan Province (East Iran). Iran J Pediatr. 2009;19(3):249-54.

Gropper SS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th ed. Belmont, CA: Wadsworth Cengage Learning; 2009. p. 488-97.

Freake HC, Sankavaram K. Zinc: Physiology, dietary sources, and requirements. In: Encyclopedia of Human Nutrition. Vol. 4. UK: Elsevier; 2013. p. 437-43. https://doi.org/10.1016/ b978-0-12-375083-9.00286-5 DOI: https://doi.org/10.1016/B978-0-12-375083-9.00286-5

Ma G, Li Y, Jin Y, Zhai F, Kok FJ, Yang X. Phytate intake and molar ratios of phytate to zinc, iron and calcium in the diets of people in China. Eur J Clin Nutr. 2007;61(3):368-74. https://doi.org/10.1038/sj.ejcn.1602513 PMid:16929240 DOI: https://doi.org/10.1038/sj.ejcn.1602513

Stipanuk MH, Caudill MA. Biochemical, Physiological, and Molecular Aspects of Human Nutrition. 3rd ed. USA: Elsevier; 2013. p. 841-2.

Frederickson CJ, Koh JY, Bush AL. The neurobiology of zinc in health and disease. Nat Rev Neurosci. 2005;6(6):449-62. PMid:15891778 DOI: https://doi.org/10.1038/nrn1671

Martini FH, Nath JL, Bartholomew EF. Fundamentals of Anatomy and Physiology. 9th ed. Canada: Pearson; 2012. p. 449-50.

Nissensohn M, Sánchez-Villegas A, Fuentes Lugo D, Henríquez Sánchez P, Doreste Alonso J, Skinner AL, et al. Effect of zinc intake on mental and motor development in infants: A meta-analysis. Int J Vitam Nutr Res. 2014;83(4):203-15. https://doi.org/10.1111/mcn.12045 PMid:25008010 DOI: https://doi.org/10.1111/mcn.12045

Levenson CW. Regulation of the NMDA receptor: Implications for neuropsychological development. Nutr Rev. 2006;64(9):428-32. PMid:17002239 DOI: https://doi.org/10.1111/j.1753-4887.2006.tb00228.x

Packer L, Sies H, Eggersdorfer M, Cadenas E. Micronutrients and Brain Health. USA: Taylor and Francis; 2010. p. 99. https://doi.org/10.1201/9781420073522 DOI: https://doi.org/10.1201/9781420073522

Xuedong Y, Xiuzhen B. Relationship between contents of microelement zinc, cuprum, and lead in hair with children’s intelligence quotient. J Math Med. 2006;4:430-2.

Chaudhary J, Jora R, Sharma P, Gehlot R, Sushil. A study of iron and zinc deficiency on short term memory in children & effect of their supplementation. Asian J Biomed Pharm Sci. 2015;5(42):12-5. https://doi.org/10.15272/ajbps.v5i42.664 DOI: https://doi.org/10.15272/ajbps.v5i42.664

Victoria P, Eugenia T, Iliana P. Zinc levels, cognitive and personality features in children with different socioeconomic backgrounds. Eur J Psychol. 2010;6(1):82-101. DOI: https://doi.org/10.5964/ejop.v6i1.173

Umamaheswari K, Bhaskaran M, Krishnamurthy G, Vasudevan H, Vasudevan K. Effect of Iron and Zinc Deficiency on Short Term Memory in Children. Indian Pediatr. 2011;48(4):289-93. https://doi.org/10.1007/s13312-011-0060-7 PMid:20972302 DOI: https://doi.org/10.1007/s13312-011-0060-7

Gogia S, Sachdev HS. Zinc supplementation for mental and motor development in children. Cochrane Database Syst Rev. 2012;12:CD007991. https://doi.org/10.1002/14651858.cd007991 PMid:23235652 DOI: https://doi.org/10.1002/14651858.CD007991

Downloads

Published

2021-04-25

How to Cite

1.
Flora R, Fajar NA, Febri F, Yuliana I, Yuliarti Y, Nurlaili N, Ikhsan I, Slamet S, Tanjung R, Aguscik A, Appulembang YA, Zulkarnain M. Zinc Intake, Zinc Serum Levels, and Intelligence in School Children in Rural Areas. Open Access Maced J Med Sci [Internet]. 2021 Apr. 25 [cited 2024 Apr. 23];9(E):394-7. Available from: https://oamjms.eu/index.php/mjms/article/view/5869

Issue

Section

Public Health Disease Control

Categories

Most read articles by the same author(s)