Analysis of Chemical Properties and Antioxidant Activity of Sambiloto (Andrographis paniculata Nees.) Leaf Tea Formula as a Functional Drink in Preventing Coronavirus Diseases and Degenerative Diseases

Authors

  • Siti Ika Fitrasyah Department of Nutrition, Tadulako University, City of Palu, Indonesia https://orcid.org/0000-0001-9291-4325
  • Ariani Ariani Department of Nutrition, Tadulako University, City of Palu, Indonesia
  • Nurdin Rahman Department of Nutrition, Tadulako University, City of Palu, Indonesia
  • Nurulfuadi Nurulfuadi Department of Nutrition, Tadulako University, City of Palu, Indonesia https://orcid.org/0000-0002-5758-8023
  • Ummu Aiman Department of Nutrition, Tadulako University, City of Palu, Indonesia
  • Devi Nadila Department of Nutrition, Tadulako University, City of Palu, Indonesia
  • Fendi Pradana Department of Nutrition, Tadulako University, City of Palu, Indonesia https://orcid.org/0000-0003-2536-8613
  • Aulia Rakhman Department of Nutrition, Tadulako University, City of Palu, Indonesia
  • Diah Ayu Hartini Department of Nutrition, Poltekkes Kemenkes Palu, City of Palu, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2021.5872

Keywords:

Andrographis Paniculata Nees, COVID-19, degenerative diseases, functional drinks, sambiloto leaf tea

Abstract

AIM: The purpose of this study was to develop a tea formula of sambiloto leaves, analyzed the chemical properties (polyphenols, tannins, water, extracts in water, total ash, water soluble ash, water-insoluble ash, insoluble acid ash, and water-soluble ash alkalinity) as well as the antioxidant capacity of the formula.

METHODS: This research was divided into two stages. The first stage was the formulation of sambiloto leaves tea and the second stage was the analysis of chemical properties (levels of polyphenols, tannins, water, extracts water, total ash, water soluble ash, water-insoluble ash, insoluble acid ash, and water soluble ash alkalinity) and antioxidant capacity analysis. The analysis was carried out on all of the sambiloto leaves tea formulas to determine the effect of the formulations on chemical properties and antioxidant capacity. This study used Microsoft Excel 2013 in data processing management.

RESULTS: The highest extract water was at F4, and the lowest was at F1. Based on the analysis, the formula of sambiloto leaves tea was in the range of 1.026–1.734%. Of all the formulas that have been prepared, sambiloto leaves tea formula F1 was obtained the best chemical and antioxidant properties among all formulas, which were composed of 100% sambiloto leaves, 5% honey, and 45% dates.

CONCLUSION: Sambiloto leaves have good antioxidant activity and can be used as a drink in the form of an infusion, such as tea. The result of brewing the sambiloto tea formula has faded green color. The polyphenol content of the sambiloto leaves tea formula still did not meet the Indonesia National Standard (≥5.2%), was 1.5–3.1%.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Kurutas EB. The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: Current state. Nutr J. 2015;15(1):71. https://doi.org/10.1186/s12937-016-0186-5 PMid:27456681

Yashin A, Yashin Y, Nemzer B. Determination of antioxidant activity in tea extracts, and their total antioxidant content. Am J Biomed Sci. 2011;3(4):322-35. https://doi.org/10.5099/aj110400322

Smith K. World Atlas of Tea: From Tea Leaf to The Cup, The World’s Teas Explored and Enjoyed. United Kingdom: Hachette UK; 2016.

Lima GP, Vianello F, Corrêa CR, da Silva Campos RA, Borguini MG. Polyphenols in fruits and vegetables and its effect on human health. Food Nutr Sci. 2014;5(11):1065-82. https://doi.org/10.4236/fns.2014.511117

Salim Z, Munadi E. Info Komoditi Tanaman Obat. Badan Pengkajian dan Pengembangan Perdagangan Kementerian Perdagangan Republik Indonesia; 2017.

Alkandahri MY, Subarnas A, Berbudi A. Review: Aktivitas immunomodulator tanaman sambiloto (Andrographis paniculata nees). Farmaka. 2018;16(3):16-21.

Tan MC, Oyong GG, Shen CC, Ragasa CY. Chemical constituents of Andrographis paniculata (Burm.f.) Nees. Int J Pharmacog Phytochem Res. 2016;8(8):1398-402.

Chao WW, Lin BF. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010;5(1):17. https://doi.org/10.1186/1749-8546-5-17

Patin EW, Zaini MA, Sulastri Y. Pengaruh variasi suhu pengeringan terhadap sifat fisiko kimia teh daun sambiloto (Andrographis paniculata). Pro Food. 2018;4(1):251-8. https://doi.org/10.31764/agrotek.v5i1.225

Nanotech Herbal Indonesia, Manfaat Dan Khasiat Daun Sambiloto Untuk Kesehatan; 2014. Available from: https://www. biofarmaka.ipb.ac.id. [Last access on 2020 Dec 20].

Cabrera C, Artacho R, Gimenez R. Beneficial effect of green tea. J Am Coll Nutr. 2006;25(2):79-99.

Hary KA. Formulasi Teh Daun Sirih Merah (Piper Crocatum) Sebagai Minuman Fungsional; 2017.

Heiss ML. Green Tea, the Harvard Common Press (RHYW); 2006.

Aji PS, Anandito RB, Nurhartadi E. Penambahan berbagai jenis madu sebagai alternatif pemanis minuman sari buah naga putih (Hylocereus undatus). Biofarmasi. 2013;11(1):13-8.

Simatupang LF, Nainggolan RJ, Nurminah M. The Effect of Ratio of Dates Juice (Phoenix dactylifera) With Kecombrang Juice (Etlingera elatior) and The Addition of Aren Sugar on The Quality of Kumbrang Juice Drink). J Rekayasa Pangan Pert. 2018;6(2):264-72. https://doi.org/10.21111/dnj.v2i1.1982

Kubo I, Masuoka N, Xiao P, Haraguchi H. Antioxidant activity of dodecyl gallate. J Agric Food Chem. 2002;50(12):3533-9. https://doi.org/10.1021/jf011250h PMid:12033824

Badan Standardisasi Nasional Indonesia (BSN). Teh Kering Dalam Kemasan: SNI No. 3836:2013. Indonesia: Badan Standardisasi Nasional; 2013. https://doi.org/10.31153/js.v15i2.114

Pandey KB, Rizvi SI. Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev. 2009;2(5):270-8. https://doi.org/10.3390/nu9091044 PMid:20716914

Baião DD, de Freitas CS, Gomes LP, da Silva D, Correa AC, Pereira PR, et al. Polyphenols from root, tubercles and grains cropped in Brazil: Chemical and nutritional characterization and their effects on human health and diseases. Nutrients. 2017;9(9):1044. PMid:28930173

D’Archivio M, Filesi C, Varì R, Scazzocchio B, Masella R. Bioavailability of the polyphenols: Status and controversies. Int J Mol Sci. 2010;11(4):1321-42. https://doi.org/10.3390/ijms11041321 PMid:20480022

Kumar S, Pandey AK. Chemistry and biological activities of flavonoids: An overview. ScientificWorldJournal. 2013;2013:162750. PMid:24470791

Nurcholis W, Priosoeryanto BP, Purwakusumah ED, Katayama T, Suzuki T. Antioxidant, cytotoxic activities and total phenolic content of four indonesian medicinal plants. J Kimia Valensi. 2012;2(4). https://doi.org/10.15408/jkv.v2i4.267

McGee H. On Food and Cooking: The Science and Lore of the Kitchen, Scribner; 2007. https://www.search.ebscohost. com/login.aspx? direct=true& scope=site &db=nlebk &db=nlabk&an=1965177. [Last accessed on 2020 Nov 22].

Fajrina A, Jubahar J, Sabirin S. Determination of Tannin Levels in Tea Bags Circulating in the Market by UV-Vis Spectrophotometry. J Farmasi Higea. J Farmasi Higea. 2016;8(2):133-42. https://doi.org/10.36656/jpfh.v3i1.313

Ameh SJ, Obodozie OO, Inyang US, Abubakar MS, Garba M. Quality control tests on Andrographis paniculata nees (Family: Acanthaceae)-an Indian ‘wonder’ plant grown in Nigeria. Trop J Pharm Res. 2010;9(4):387-94. https://doi.org/10.4314/tjpr.v9i4.58937

Okhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: A review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014;4(3):213-22. https://doi.org/10.1016/s2222-1808(14)60509-0

Husna NE. Leubiem fish (Canthidermis maculatus) jerky with variation of production methods, type of sugar, and drying methods. J Teknol Industri Pertnian Indones. 2014;6(3):76-81. https://doi.org/10.17969/jtipi.v6i3.2316.

Schwalfenberg GK. The alkaline diet: Is there evidence that an alkaline pH diet benefits health? J Environ Public Health. 2012;2012:727630.https://doi.org/10.1155/2012/727630 PMid:22013455

Nielsen SS. Food Analysis (Food Science Text Series). 4th ed. Berlin: Springer; 2010.

Kedare SB, Singh RP. Genesis and development of DPPH method of antioxidant assay. J Food Sci Technol. 2011;48(4):412- 22. https://doi.org/10.1007/s13197-011-0251-1 PMid:23572765

Nariya P, Nariya M, Shukla V, Acharya R, Bhalodia N. In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark. AYU. 2013;34(1):124-8. https://doi.org/10.4103/0974-8520.115451 PMid:24049418

Jun M, Fu HY, Hong J, Wan X, Yang CS, Ho CT. Comparison of antioxidant activities of isoflavones from kudzu root (Pueraria lobata Ohwi). J Food Sci. 2003;68(6):2117-22. https://doi.org/10.1111/j.1365-2621.2003.tb07029.x

Saranya P, Geetha A, Selvamathy SM. The antioxidant and H+K+ atpase inhibitory effect of Andrographis paniculata and andrographolide-in vitro and in vivo studies. Pharmacologyonline. 2010;1:356-76.

Rais IR. Aktivitas antioksidan ekstrak Andrographis paniculata (Burm.f.) ness dengan dua perbedaan penguapan. Pharmaciana. 2016;6(1):95-100. https://doi.org/10.12928/pharmaciana.v6i1.3226

Downloads

Published

2021-04-29

How to Cite

1.
Fitrasyah SI, Ariani A, Rahman N, Nurulfuadi N, Aiman U, Nadila D, Pradana F, Rakhman A, Hartini DA. Analysis of Chemical Properties and Antioxidant Activity of Sambiloto (Andrographis paniculata Nees.) Leaf Tea Formula as a Functional Drink in Preventing Coronavirus Diseases and Degenerative Diseases. Open Access Maced J Med Sci [Internet]. 2021 Apr. 29 [cited 2021 Oct. 19];9(A):196-201. Available from: https://oamjms.eu/index.php/mjms/article/view/5872