Myringoplasty with Morphological Rationale of Application of Xenoperitoneum Decellularized Matrix in Experiment

Authors

  • Dias Yesniyazov Department of Surgical Diseases, Karaganda Medical University, Karaganda, Kazakhstan
  • Tussupbekova Maida Department of Surgical Diseases, Karaganda Medical University, Karaganda, Kazakhstan
  • Nurkasi Abatov Department of Surgical Diseases, Karaganda Medical University, Karaganda, Kazakhstan
  • Yekaterina Yukhnevich Department of Surgical Diseases, Karaganda Medical University, Karaganda, Kazakhstan
  • Ruslan Badyrov Department of Surgical Diseases, Karaganda Medical University, Karaganda, Kazakhstan

DOI:

https://doi.org/10.3889/oamjms.2021.5897

Keywords:

Decellularized matrix, Xenoperitoneum, Biological implant, Myringoplasty, Tympanic membrane perforation

Abstract

AIM: The aim of the study is to create a myringoplasty technique with decellularized matrix of xenoperitoneum in an experiment on rabbits with morphological rationale of a new biological material application.

 METHODS:

Sixty rabbits were included in research. The animals were randomly divided in two groups for use the bioimplant – decellularized matrix of xenoperitoneum and control. Each subgroup corresponded to the observation period and the removal of the animal from the experiment. Observation period was: 7 days, 21 days and 30 days after myringoplasty.

RESULT:

The maturation of connective tissue in both groups was completed by the 30th day. But the change in the exudative phase into the proliferative phase occurred faster and the dynamics of reparative processes after myringoplasty were better in experimental group.

CONCLUSION:

The use the decellularized matrix of xenoperitoneum had better reparative properties

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References

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Published

2021-10-05

How to Cite

1.
Yesniyazov D, Maida T, Abatov N, Yukhnevich Y, Badyrov R. Myringoplasty with Morphological Rationale of Application of Xenoperitoneum Decellularized Matrix in Experiment. Open Access Maced J Med Sci [Internet]. 2021 Oct. 5 [cited 2021 Dec. 4];9(A):811-6. Available from: https://oamjms.eu/index.php/mjms/article/view/5897

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Section

Pathophysiology

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