The New Detection Method of Ovarian Follicle Development Using Digitized Wide Area Measurement

Noviyanti Noviyanti; Yuyun Yueniwati; Bambang  Rahardjo; Karyono Mintaroem; Erick Khristian

doi:10.3889/oamjms.2021.6122

Authors

Noviyanti Noviyanti Doctoral Program in Medical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Midwifery Program, School of Health Sciences Jenderal Achmad Yani Cimahi, West Java, Indonesia
Yuyun Yueniwati Department of Radiology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia https://orcid.org/0000-0001-9932-2015
Bambang Rahardjo Department of Obstetric and Gynaecologic, Dr. Saiful Anwar General Hospital, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia
Karyono Mintaroem Department of Anatomical Pathology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia
Erick Khristian Department of Cytohistotechnology, Medical Technology Laboratory, School of Health Sciences Jenderal Achmad Yani Cimahi, West Java, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2021.6122

Keywords:

The Measurement of Follicle Development, Estradiol

Abstract

METHODS: The research method used in this research was experimental laboratory with pre-and posttest only control group design.

RESULTS: The result shows that the extradiol level which has range of 26.30–31.03 from 28 experimental animals measured, this showed more measurement diameter which has not had measurement addition compare with the wide percentage of measurement. The result shows strong correlation between digitalized measured wide follicles to the changing of estradiol level with value of 0.453. The result of comparation between estradiol level and measured diameter shows weak correlation. This shows that manual measurement of follicle diameter still weak to the changing of estradiol level.

CONCLUSION: There is strong correlation between measured wide area follicle used ImageJ applications to the changing of estradiol level compare to the measurement of follicle diameter.

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References

Fritz MA, Speroff L. Clinical Gynecologic Endocrinology and Infertility. 8th ed. Philadelphia, PA: LWW; 2011.

Altmäe S, Haller K, Peters M, Saare M, Hovatta O, Stavreus- Evers A, et al. Aromatase gene (CYP19A1) variants, female infertility and ovarian stimulation outcome: A preliminary report. Reprod Biomed Online. 2009;18(5):651-7. https://doi.org/10.1016/s1472-6483(10)60009-0 PMid:19549443 DOI: https://doi.org/10.1016/S1472-6483(10)60009-0

Heffner LJ, Schust DJ. The Reproductive System at a Glance (at a Glance Sistem Reproduksi). 3rd ed. Hoboken, New Jersey: Wiley-Blackwell Publishing; 2010.

Ciptadi G, Susilawati T, Siswanto B, Karima HN. The effectiveness of adding gonadotropin hormone to the mSOF maturation medium on the level of oocyte maturation. J Ternak Trop. 2012;12:108-14.

Zainuddin M. Metodologi Penelitian Kefarmasian dan Kesehatan. Surabaya: Airlangga University Press; 2011.

Hafid A, Karja N, Setiadi M. Kompetensi maturasi dan fertilisasi oosit domba prapubertas secara in vitro. (Developmental competence of maturation and fertilization prepubertal sheep oocytes in vitro). J Vet. 2017;18:51-8. https://doi.org/10.19087/jveteriner.2017.18.1.51 DOI: https://doi.org/10.19087/jveteriner.2017.18.1.51

Satria YE, Yusuf TL, Amrozi. Determination of optimal mating time based on ovarian ultrasonography with clinical symptoms of estrus in etawa crossbreeds. J Vet. 2016;17(1):64-70. https://doi.org/10.19087/jveteriner.2016.17.1.64 DOI: https://doi.org/10.19087/jveteriner.2016.17.1.64

Kiptiyah K, Widodo W, Ciptadi G, Aulanni’am A, Widodo MA, Sumitro SB. 10-Gingerol as an inducer of apoptosis through HTR1A in cumulus cells: In-vitro and in-silico studies. J Taibah Univ Med Sci. 2017;12:397-406. https://doi.org/10.1016/j.jtumed.2017.05.012 PMid:31435270 DOI: https://doi.org/10.1016/j.jtumed.2017.05.012

Syarif RA, Kadarsih SS, Meiyanto E, Wahyuningsih M. Sr. Effect of curcumin on estrogen secretion and expression of estrogen receptor beta porcine granulosa cell culture moderate follicles. J Kedokt Brawijaya. 2016;29(1):1-4.

Strauss JF, Barbieri RL. Yen and Jaffe’s Reproductive Endocrinology. Amsterdam, Netherlands: Elsevier Health Sciences; 2014.

Vrtačnik P, Ostanek B, Mencej-Bedrač S, Marc J. The many faces of estrogen signaling. Biochem Med. 2014;24(3):329-42. https://doi.org/10.11613/bm.2014.035 PMid:25351351 DOI: https://doi.org/10.11613/BM.2014.035

Noviyanti N, Yueniwati Y, Ali M, Rahardjo B, Permatasari GW. Cyclea barbata miers ethanol extract and coclaurine induce estrogen receptor α _in the development of follicle pre-ovulation. Open Access Maced J Med Sci. 2020;8(A):434-40. https://doi.org/10.3889/oamjms.2020.4418 DOI: https://doi.org/10.3889/oamjms.2020.4418

Hikmah N. Effect of Soy Tempe Flour Extract on Uterus Structure of Mice (Mus musculus) Swiss Webster Ovarectomy Strain. Jember: Universitas Jember; 2015.

Hismayasari IB, Rahayu S, Marhendra AP. Ovary maturation stages histology and follicles diameter of Melanotaenia boesemani rainbowfish ovary from district of North Ayamaru, Maybrat Regency, west Papua. J Morphol Sci. 2015;32(3):157-64. https://doi.org/10.4322/jms.082914 DOI: https://doi.org/10.4322/jms.082914