The Effect of Anthropometry on Refractive Error and Ocular Biometry in Children with β Thalassemia Major

Authors

  • Aryani Atiyatul Amra Department of Ophthalmology, Faculty of Medicine, University of Sumatera Utara, Medan, Indonesia https://orcid.org/0000-0001-6422-4079
  • Fithria Aldy Department of Ophthalmology, Faculty of Medicine, University of Sumatera Utara, Medan, Indonesia
  • Bidasari Lubis Department of Paediatrics, Faculty of Medicine, University of Sumatera Utara, Medan, Indonesia
  • Elyani Rahman Department of Ophthalmology, Faculty of Medicine, University of Sumatera Utara, Medan, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2021.6280

Keywords:

β-Thalassemia major, Anthropometry, Refractive abnormalities, Ocular biometry

Abstract

AIM: The objective of the study was to evaluate the effect of anthropometry on refractive error and ocular biometry in children with β-thalassemia major.

METHOD: This study was an analytical observational with a cross-sectional design which conducted in 1 day care thalassemia pediatric Department and Ophthalmology Department of North Sumatera University Hospital from February to April 2019. The study included 44 children with β-thalassemia major.

RESULTS: Anthropometric analysis of refractive errors did not show a significant correlation, whereas anthropometric analysis on biometry showed a significant correlation between height and axial length of the right eye (p = 0.004) and left eye (p = 0.043), then showed significant correlations between height and anterior chamber depth of the right eye (p = 0.027) and left eye (p = 0.016).

CONCLUSION: Height affects the axial length and anterior chamber depth, but there are no anthropometric variables that affect refractive errors in this study.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

De Baun MR, Frei-Jones MJ, Vichinsky EP. Thalassemia syndromes. In: Kliegman MR, Stanton BF, St Geme JW, Schor NF, editors. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016. p. 2349-53. https://doi.org/10.1016/b978-1-4377-0755-7.00714-4 DOI: https://doi.org/10.1016/B978-1-4377-0755-7.00714-4

Wahidiyat PA, Gatot D, Tjitrasari T, Ringoringo H, Marzuki N, Taufani R, et al. Phenotypic diversity in beta HbE thalassemia patient. Pediatr Indones. 2006;46:82-6. https://doi.org/10.14238/pi46.2.2006.82-6 DOI: https://doi.org/10.14238/pi46.2.2006.82-6

Wahidyat I, Wahidayat PA. Genetic problems at present and their challenges in the future: Thalassemia as a model. Pediatr Indones. 2006;46(5):189-94. DOI: https://doi.org/10.14238/pi46.5.2006.189-94

Kundu A, Ganguly P, Sinharay A, Patil P, Sharma K, Bandyopadhyay M. A study to assess the ocular biometric parameters and prevalence of refractive errors among thalassemic children in a rural based tertiary hospital. Int J Health Sci Res. 2017;7(4):160-5.

Elkitkat RS, El Shazly AA, Ebeid WM, Deghedy MR. Relation of anthropometric measurements to ocular biometric changes and refractive error in children with thalassemia. Eur J Ophthalmol. 2016;5:212-9. https://doi.org/10.5301/ejo.5000903 DOI: https://doi.org/10.5301/ejo.5000903

Rahman E, Amra AA, Aldy F, Sari MD, Lubis B. Comparison of axial length, anterior chamber depth, lens thickness measurement using biometry in thalassemia β mayor children toward emmetropia children. Int J Sci Res Publ. 2018;8(2):415-9.

Amini F, Jafari A, Eslamian L, Sharifzadeh S. A cephalometric study on craniofacial morphology of Iranian children with beta-thalassemia major. Orthod Craniofac Res. 2007;10(1):36-44. https://doi.org/10.1111/j.1601-6343.2007.00380.x PMid:17284245 DOI: https://doi.org/10.1111/j.1601-6343.2007.00380.x

Jonas JB, Nangia V, Gupta R, Khare A, Sinha A, Agarwal S, et al. Anterior chamber depth and its associations with ocular and general parameters in adults. Clin Exp Ophthalmol. 2012;40(6):550-6. https://doi.org/10.1111/j.1442-9071.2011.02748.x PMid:22171546 DOI: https://doi.org/10.1111/j.1442-9071.2011.02748.x

Shih YF, Chiang TF, Lin LL. Lens thickness changes among schoolchildren in Taiwan. Invest Ophthalmol Vis Sci. 2009;50(6):2637-44. https://doi.org/10.1167/iovs.08-3090 PMid:19234352 DOI: https://doi.org/10.1167/iovs.08-3090

Tideman JW, Polling JR, Jaddoe VW, Vingerling JR, Klaver CW. Environmental risk factors can reduce axial length elongation and myopia incidence in 6-to 9-year-old children. Ophthalmology. 2019;126(1):127-36. https://doi.org/10.1016/j.ophtha.2018.06.029 DOI: https://doi.org/10.1016/j.ophtha.2018.06.029

PMid:30146089

Ip JM, Robaei D, Kifley A, Wang JJ, Rose KA, Mitchell P. Prevalence of hyperopia and associations with eye findings in 6-and 12-year-olds. Ophthalmology. 2008;115(4):678-85. https://doi.org/10.1016/j.ophtha.2007.04.061 PMid:17664011 DOI: https://doi.org/10.1016/j.ophtha.2007.04.061

Lai YH, Hsu HT, Wang HZ, Chang CH, Chang SJ. Astigmatism in preschool children in Taiwan. J AAPOS. 2010;14(2):150-4. PMid:20451858 DOI: https://doi.org/10.1016/j.jaapos.2009.12.168

Downloads

Published

2021-05-14

How to Cite

1.
Amra AA, Aldy F, Lubis B, Rahman E. The Effect of Anthropometry on Refractive Error and Ocular Biometry in Children with β Thalassemia Major. Open Access Maced J Med Sci [Internet]. 2021 May 14 [cited 2024 Dec. 4];9(T3):64-7. Available from: https://oamjms.eu/index.php/mjms/article/view/6280