Blood Pressure Differences in Nephrotic Syndrome Patients with Steroid Resistant Nephrotic Syndrome Patients and Steroid Sensitive Nephrotic Syndrome

Muhammad Akbar; Oke Rina Ramayani; Gema Nazri Yanni

doi:10.3889/oamjms.2021.6315

Authors

Muhammad Akbar Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Oke Rina Ramayani Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Gema Nazri Yanni Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2021.6315

Keywords:

Nephrotic syndrome, Steroid resistant, Sensitive steroids, Blood pressure

Abstract

BACKGROUND: Syndrome nephrotic is the most common kidney disease found in pediatric kidney disease, classification based on clinical response to steroids or histopathological characteristics. Increased blood pressure in steroid-resistant nephrotic syndrome (NS) is still a complication to be aware of in cases of NS.

AIM: The aim of the study was to determine the differences in systolic and diastolic blood pressure in patients with steroid-sensitive NS and steroid-resistant NS.

METHODS: Analytical correctional study in 50 children with NS divided into 25 Steroid Resistant NS (SRNS) groups and 25 steroid sensitive NS (SSNS) people who met inclusion and exclusion criteria to assess systolic and diastolic blood pressure in each group in pediatric nephrology division of the general hospital of Haji Adam Malik Medan.

RESULTS: There is a difference in systolic blood pressure in the SRNS and SSNS groups which mean p = 0.024 and there is no difference in diastolic blood pressure in the SRNS group with SSNS p = 0.358. If linked levels of proteinuria to blood pressure, systolic and diastolic in both groups found no significant link p>0.05 high blood pressure with the degree of proteinuria in both group.

CONCLUSION: There are differences in systolic blood pressure in the SRNS and SSNS groups.

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