Autogenous Onlay Graft with Compression Plate for Treatment of Persistent Humeral Shaft Aseptic Non-union with Failed Previous Surgery
DOI:
https://doi.org/10.3889/oamjms.2021.6511Keywords:
Only graft, Aseptic nonunion humerus, Compression plateAbstract
BACKGROUND: The humeral shaft fractures have a good rate of union, despite this fact, still there is a significant rate of nonunion after nonoperative treatment and more often after operative treatment.
AIM: The aim of the study is to evaluate the autogenous onlay graft with compression plate for treatment of persistent humeral shaft non-union with failed previous surgery both radiological and functional outcome.
MATERIALS AND METHODS: A prospective study on twenty patients having persistent aseptic non-union age between 20 and 60 years old, after failed surgical treatment of fractures humeral shaft in Al-Zahra teaching and Al-Kindy teaching hospitals, while infected nonunion, diabetes mellitus, secondary metastasis, smoking, alcoholism, and patients on long medication with corticosteroid were excluded from the study. All our patients were treated with corticocancellous onlay bone grafting harvesting from the ipsilateral upper tibia and compression plating (graft parallel to plate) and follow-up for at least 18 months post-operative to evaluate both radiology and functional using Mayo elbow performance index.
RESULTS: All the patients ended with a solid union without hardware failure, and no one patient needs further surgery, even with significant resorption of the graft, there is a good chance of graft re-calcification and solid union with good to excellent functional outcome.
CONCLUSION: Very successful solid union results achieve in those patients with established aseptic nonunion and pseudoarthrosis of the humerus.Downloads
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Billings A, Coleman SS. Long-term follow-up of the persistent humeral shaft. Iowa Orthop J. 1999;19:31-4. PMid:10847514
Wenzl ME, Porté T, Fuchs S, Jürgens C. Methods for the reconstruction and osteosynthesis of pseudarthrosis of the humerus. Trauma Berufskrankheit. 2003;5(1):s86-91. DOI: https://doi.org/10.1007/s10039-002-0606-y
van de Wall BJ, Ochen Y, Beeres FJ, Babst R, Link BC, Heng M, et al. Conservative vs. operative treatment for humeral shaft fractures: A meta-analysis and systematic review of randomized clinical trials and observational studies. J Shoulder Elbow Surg. 2020;29(7):1493-504. https://doi.org/10.1016/j.jse.2020.01.072 PMid:32249144 DOI: https://doi.org/10.1016/j.jse.2020.01.072
Westrick E, Hamilton B, Toogood P, Henley B, Firoozabadi R. Humeral shaft fractures: Results of operative and non-operative treatment. Int Orthop. 2017;41(2):385-95. https://doi.org/10.1007/s00264-016-3210-7 PMid:27150488 DOI: https://doi.org/10.1007/s00264-016-3210-7
Maresca A, Sangiovanni P, Cerbasi S, Politano R, Fantasia R, Commessatti M, et al. Why a surgically treated humeral shaft fracture became a nonunion: A review of 11 years in two trauma centers. Musculoskelet Surg. 2017;101(Suppl 2):105-12. https://doi.org/10.1007/s12306-017-0509-5 PMid:29052035 DOI: https://doi.org/10.1007/s12306-017-0509-5
Panagiotis M. Classification of non-union. Injury. 2005;36(Suppl 4):S30-7. PMid:16291321 DOI: https://doi.org/10.1016/j.injury.2005.10.008
Peters RM, Claessen FM, Doornberg JN, Kolovich GP, Diercks RL, van den Bekerom MP. Union rate after operative treatment of humeral shaft nonunion--A systematic review. Injury. 2015;46(12):2314-24. https://doi.org/10.1016/j.injury.2015.09.041 PMid:26499226 DOI: https://doi.org/10.1016/j.injury.2015.09.041
Kim JW, Oh CW, Byun YS, Kim JJ, Park KC. A prospective randomized study of operative treatment for noncomminuted humeral shaft fractures: conventional open plating versus minimal invasive plate osteosynthesis. J Orthop Trauma. 2015;29(4):189-94. https://doi.org/10.1097/bot.0000000000000232 PMid:25210833 DOI: https://doi.org/10.1097/BOT.0000000000000232
Babhulkar S, Babhulkar S, Vasudev A. Recalcitrant aseptic atrophic nonunion of the shaft of the humerus after the failure of surgical treatment: Management by excision of non-union, bone grafting, and stabilization by LCP in different modes. Injury. 2017;48:S33-43. https://doi.org/10.1016/s0020-1383(17)30492-8 PMid:28802419 DOI: https://doi.org/10.1016/S0020-1383(17)30492-8
Longo UG, Franceschi F, Loppini M, Maffulli N, Denaro V. Rating systems for evaluation of the elbow. Br Med Bull. 2008;87(1):131-61. https://doi.org/10.1093/bmb/ldn023 PMid:18539627 DOI: https://doi.org/10.1093/bmb/ldn023
Morshed S. Current options for determining fracture union. Adv Med. 2014;2014:708574. PMid:26556422 DOI: https://doi.org/10.1155/2014/708574
Nicholson JA, Makaram N, Simpson A, Keating JF. Fracture nonunion in long bones: A literature review of risk factors and surgical management. Injury. 2020;52(Suppl 2):S3-11. https:// doi.org/10.1016/j.injury.2020.11.029 PMid:33221036 DOI: https://doi.org/10.1016/j.injury.2020.11.029
Olson JJ, Entezari V, Vallier HA. Risk factors for nonunion after traumatic humeral shaft fractures in adults. JSES Int. 2020;4(4):734-8. https://doi.org/10.1016/j.jseint.2020.06.009 DOI: https://doi.org/10.1016/j.jseint.2020.06.009
PMid:3334520814. Rollo G, Prkic A, Bisaccia M, Eygendaal D, Pichierri P, Marsilio A, et al. Grafting and fixation after aseptic non-union of the humeral shaft: A case series. J Clin Orthop Trauma. 2020;11(Suppl 1):S51-5. https://doi.org/10.1016/j.jcot.2019.08.020 PMid:31992917 DOI: https://doi.org/10.1016/j.jcot.2019.08.020
Singh AK, Arun GR, Narsaria N, Srivastava A. Treatment of non-union of humerus diaphyseal fractures: A prospective study comparing interlocking nail and locking compression plate. Arch Orthop Trauma Surg. 2014;134(7):947-53. https://doi.org/10.1007/s00402-014-1973-0 PMid:24853958 DOI: https://doi.org/10.1007/s00402-014-1973-0
Trotter DH, Dobozi W. Nonunion of the humerus: Rigid fixation, bone grafting, and adjunctive bone cement. Clin Orthop Relat Res. 1986;204:162-8. https://doi.org/10.1097/00003086-198603000-00018 PMid:3514032 DOI: https://doi.org/10.1097/00003086-198603000-00018
Kerfant N, Valenti P, Kilinc AS, Falcone MO. Free vascularised fibular graft in multi-operated patients for an aseptic non-union of the humerus with a segmental defect: Surgical technique and results. Orthop Traumatol Surg Res. 2012;98(5):603-7. https://doi.org/10.1016/j.otsr.2012.03.013 DOI: https://doi.org/10.1016/j.otsr.2012.03.013
Kalra GS, Goel P, Singh PK. Reconstruction of post-traumatic long bone defect with vascularized free fibula: A series of 28 cases. Indian J Plast Surg. 2013;46(3):543-8. https://doi.org/10.4103/0970-0358.122013 PMid:24459347 DOI: https://doi.org/10.4103/0970-0358.122013
Hsu TL, Chiu FY, Chen CM, Chen TH. Treatment of nonunion of humeral shaft fracture with dynamic compression plate and cancellous bone graft. J Chin Med Assoc. 2005;68(2):73-6. https://doi.org/10.1016/s1726-4901(09)70138-8 PMid:15759818 DOI: https://doi.org/10.1016/S1726-4901(09)70138-8
Collie L, Cooney W, Kelly P. Nonunions of the humeral shaft. Orthop Trans. 1983;7:517.
Lin CL, Fang CK, Chiu FY, Chen CM, Chen TH. Revision with dynamic compression plate and cancellous bone graft for aseptic nonunion after surgical treatment of humeral shaft fracture. J Trauma Acute Care Surg. 2009;67(6):1393-6. https:// doi.org/10.1097/ta.0b013e31818c1595 PMid:20009693 DOI: https://doi.org/10.1097/TA.0b013e31818c1595
Belayneh R, Lott A, Haglin J, Konda S, Leucht P, Egol K. Final outcomes of radial nerve palsy associated with humeral shaft fracture and nonunion. J Orthop Traumatol. 2019;20(1):18. https://doi.org/10.1186/s10195-019-0526-2 PMid:30923949 DOI: https://doi.org/10.1186/s10195-019-0526-2
Kalfas IH. Principles of bone healing. Neurosurg Focus. 2001;10(4):e1. PMid:16732625 DOI: https://doi.org/10.3171/foc.2001.10.4.2
Ansari M. Bone tissue regeneration: Biology, strategies, and interface studies. Prog Biomater. 2019;8(4):223-37. https://doi.org/10.1007/s40204-019-00125-z PMid:31768895 DOI: https://doi.org/10.1007/s40204-019-00125-z
Baldwin P, Li DJ, Auston DA, Mir HS, Yoon RS, Koval KJ. Autograft, allograft, and bone graft substitutes clinical evidence and indications for use in the setting of orthopaedic trauma surgery. J Orthop Trauma. 2019;33(4):203-13. https://doi.org/10.1097/bot.0000000000001420 PMid:30633080 DOI: https://doi.org/10.1097/BOT.0000000000001420
Roberts TT, Rosenbaum AJ. Bone grafts, bone substitutes, and orthobiologics: The bridge between basic science and clinical advancements in fracture healing. Organogenesis. 2012;8(4):114-24. https://doi.org/10.4161/org.23306 PMid:23247591 DOI: https://doi.org/10.4161/org.23306
Salgado AJ, Coutinho OP, Reis RL. Bone tissue engineering: State of the art and future trends. Macromol Biosci. 2004;4(8):743-65. https://doi.org/10.1002/mabi.200400026 PMid:15468269 DOI: https://doi.org/10.1002/mabi.200400026
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Copyright (c) 2021 Falih Waheed Hashmi , Mohammed Baqir Al-Shara, Mohammed Al-Edanni (Author)
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