Uncrossmatched Blood Transfusion for Resuscitation Patients at the Emergency Department

Authors

  • Korakot Apiratwarakul Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand https://orcid.org/0000-0002-1984-0865
  • Sivit Chanthawatthanarak Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
  • Piyathida Klawkla Department of Emergency Medicine, Bangkok Hospital Phetchaburi, Phetchaburi, Thailand
  • Kamonwon Ienghong Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand https://orcid.org/0000-0003-0328-4128
  • Vajarabhongsa Bhudhisawasdi Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
  • Takaaki Suzuki Department of Emergency and Critical Care Medicine, University of Tsukuba Hospital, Tsukuba, Japan

DOI:

https://doi.org/10.3889/oamjms.2021.6543

Keywords:

Blood transfusion, Blood group incompatibility, Emergency departments, Death rate, Mortality rate

Abstract

BACKGROUND: Patients with uncontrolled blood loss often require immediate blood transfusion after the bleeding is stopped. If it is an emergency situation, blood that has not been tested for compatibility (uncrossmatched red blood cell [URBC] products) can be used. However, no studies have been conducted to evaluate the effectiveness of this protocol.

AIM: The aim of the study is to evaluate the effectiveness of URBC transfusion in Srinagarind Hospital’s emergency department (ED).

METHODS: This was a cross-sectional study that reviewed the medical records of ninty Thai patients over 18 years of age who received at least one unit of blood through URBC transfusion in the Srinagarind Hospital ED from September 2016 to August 2018.

RESULTS: The average age of the patients was 47.23 ± 18.2 years, and 73.3% were male. A total of 149 units of URBC were provided, with 54.44% of recipients being trauma patients and 27.78% being gastrointestinal bleeding patients. The 24-h and in-hospital mortality rates were 58.89 and 72.22%, respectively. There were no cases of acute blood transfusion complications or inappropriate URBC transfusion.

CONCLUSIONS: The transfusion of URBC necessary in patients with uncontrolled bleeding. No complications were found due to acute blood transfusion.

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References

American College of Surgeons’ Committee on Trauma. Advanced Trauma Life Support (ATLS). 10th ed. Chicago: American College of Surgeons; 2017. p. 52-5.

Inaba K, Teixeira P, Shulman I, Nelson J, Lee J, Salim A, et al. The impact of uncross-matched blood transfusion on the need for massive transfusion and mortality: analysis of 5,166 uncross-matched units. J Trauma. 2008;65(6):1222-6. http://doi.org/10.1097/TA.0b013e31818e8ff3 PMid:19077605 DOI: https://doi.org/10.1097/TA.0b013e31818e8ff3

Harris CT, Totten M, Davenport D, Ye Z, O’Brien J, Williams D, et al. Experience with uncrossmatched blood refrigerator in emergency department. Trauma Surg Acute Care Open. 2018;3(1):e000184. http://doi.org/10.1136/tsaco-2018-000184 PMid:30402556 DOI: https://doi.org/10.1136/tsaco-2018-000184

Massive Hemorrhage and Emergency Transfusion. Professional Education; 2016. Available from: https://professionaleducation.blood.ca/en/transfusion/clinical-guide-transfusion.

Ball CG, Salomone JP, Shaz B, Dente CJ, Tallah C, Anderson K, et al. Uncrossmatched blood transfusions for trauma patients in the emergency department: Incidence, outcomes and recommendations. Can J Surg. 2011;54(2):111-5. http://doi.org/10.1503/cjs.032009 PMid:21251416 DOI: https://doi.org/10.1503/cjs.032009

Murthi SB, Dutton RP, Edelman BB, Scalea TM, Hess JR. Transfusion medicine in trauma patients. Expert Rev Hematol. 2008;1(1):99-109. http://doi.org/10.1586/17474086.1.1.99 PMid:21083009 DOI: https://doi.org/10.1586/17474086.1.1.99

American College of Surgeons’ Committee on Trauma. Advanced Trauma Life Support (ATLS). 9th ed. Chicago: American college of surgeons; 2012. p. 69-70.

Nunez TC, Voskresensky IV, Dossett LA, Shinall R, Dutton WD, Cotton BA. Early prediction of massive transfusion in trauma: Simple as ABC (assessment of blood consumption)?J Trauma. 2009;66(2):346-52. http://doi.org/10.1097/TA.0b013e3181961c35 PMid:19204506 DOI: https://doi.org/10.1097/TA.0b013e3181961c35

Hamidi M, Zeeshan M, Kulvatunyou N, Adun E, O’Keeffe T, Zakaria ER, et al. Outcomes after massive transfusion in trauma patients: Variability among trauma centers. J Surg Res. 2019;234:110-5. http://doi.org/10.1016/j.jss.2018.09.018 PMid:30527461 DOI: https://doi.org/10.1016/j.jss.2018.09.018

Kang BH, Choi D, Cho J, Kwon J, Huh Y, Moon J, et al. Efficacy of uncross-matched type o packed red blood cell transfusion to traumatic shock patients: A propensity score match study. J Korean Med Sci. 2017;32(12):2058-63. http://doi.org/10.3346/jkms.2017.32.12.2058 PMid:29115091 DOI: https://doi.org/10.3346/jkms.2017.32.12.2058

Mulay SB, Jaben EA, Johnson P, Badjie K, Stubbs JR. Risks and adverse outcomes associated with emergency-release red blood cell transfusion. Transfusion. 2013;53(7):1416-20. http://doi.org/10.1111/j.1537-2995.2012.03922.x PMid:23067326 DOI: https://doi.org/10.1111/j.1537-2995.2012.03922.x

Goodell PP, Uhl L, Mohammed M, Powers AA. Risk of hemolytic transfusion reactions following emergency-release RBC transfusion. Am J Clin Pathol. 2010;134(2):202-6. http://doi.org/10.1309/AJCP9OFJN7FLTXDB PMid:20660321 DOI: https://doi.org/10.1309/AJCP9OFJN7FLTXDB

Nunez TC, Dutton WD, May AK, Holcomb JB, Young PP, Cotton BA. Emergency department blood transfusion predicts early massive transfusion and early blood component requirement. Transfusion. 2010;50(9):1914-20. http://doi.org/10.1111/j.1537-2995.2010.02682.x PMid:20456707 DOI: https://doi.org/10.1111/j.1537-2995.2010.02682.x

Huang GS, Dunham CM. Mortality outcomes in trauma patients undergoing prehospital red blood cell transfusion: A systematic literature review. Int J Burns Trauma. 2017;7(2):17-26. PMid:28533934

Apiratwarakul K, Phanthachai K, Gaysonsiri D, Bhudhisawasdi V, Artpru R. Airway management with the laryngeal mask airway (LMA) in emergency medical services. J Med Assoc Thai. 2021;104(Suppl 1):S8-11. https://doi.org/10.35755/jmedassocthai.2021.S01.12131 DOI: https://doi.org/10.35755/jmedassocthai.2021.S01.12131

Ienghong K, Suzuki T, Phengsavanh A, Nasaarn T. Competency of ultrasound knowledge of laos emergency medicine residents during international elective rotation in Thailand. J Med Assoc Thai. 2021;104(Suppl 1):S20-4. https://doi.org/10.35755/jmedassocthai.2021.S01.12138 DOI: https://doi.org/10.35755/jmedassocthai.2021.S01.12138

Ienghong K, Srikumpa P, Apiratwarakul K, Phungoen P, Gaysonsiri D, Bhudhisawasdi V. Factors associated with transfusion of uncross-matched type-O packed red cells for acute upper gastrointestinal hemorrhage. J Med Assoc Thai. 2020;103 Suppl 6:22-6.

Ruttanaseeha W, Serewiwattana N, Ienghong K, Buranasakda M, Apiratwarakul K, Tiamkao S. Accuracy of triage by nurses and doctors in the emergency department. J Med Assoc Thai. 2020;103(Suppl 6):1-3.

Apiratwarakul K, Ienghong K, Suzuki T, Celebi I, Bhudhisawasdi V, Tiamkao S. Using routine ambulance inspection report application to reduce wasted time in emergency medical services. Open Access Maced J Med Sci. 2021;9(E):298-301. https://doi.org/10.3889/oamjms.2021.6022 DOI: https://doi.org/10.3889/oamjms.2021.6022

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Published

2021-07-15

How to Cite

1.
Apiratwarakul K, Chanthawatthanarak S, Klawkla P, Ienghong K, Bhudhisawasdi V, Suzuki T. Uncrossmatched Blood Transfusion for Resuscitation Patients at the Emergency Department. Open Access Maced J Med Sci [Internet]. 2021 Jul. 15 [cited 2021 Sep. 20];9(E):496-9. Available from: https://oamjms.eu/index.php/mjms/article/view/6543

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