Effect of Artificial Carbon Dioxide-Rich Water Immersion on Peripheral Blood Flow in Healthy Volunteers: Preliminary Study about Artificial Carbon Dioxide-Rich Water

Andi Rizky Arbaim Hasyar; Haerani Rasyid; Irfan Idris; Irawan Yusuf

doi:10.3889/oamjms.2021.6591

Authors

Andi Rizky Arbaim Hasyar Postgraduate Program, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia https://orcid.org/0000-0003-2230-8754
Haerani Rasyid Department of Internal Medicine, Nephrology and Hypertension Division, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
Irfan Idris Department of Physiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia https://orcid.org/0000-0002-7350-8687
Irawan Yusuf Department of Physiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2021.6591

Keywords:

Carbon dioxide, Regional blood flow, Balneotherapy, Laser Doppler flowmetry

Abstract

BACKGROUND: Peripheral blood circulation disorder is one of the global health problems. Balneotherapy that uses CO2 springs may be one of the complementary treatment options. The device to produce artificial CO2-rich water is needed to achieve an improvement effect, at least almost like the improvement effect of natural balneotherapy.

AIM: This study aims to investigate the effect of artificial CO2-rich water immersion on peripheral blood flow using Bicarbonated JesC CREA BC-2000.

METHODS AND MATERIALS: Thirty-nine healthy volunteers participated in this study. Each subject immersed both of their legs in a mixed solution from water and CO2 at temperature 38°C. This solution was mixed using a device, namely, “Bicarbonated JesC CREA BC-2000”. Peripheral blood flow was measured for 5 min before immersion (in this study, we denoted it as the mean basal blood flow), 10 min during immersion, and 5 min after immersion using pocket JMS laser Doppler flowmetry MBF-IIA. Repeated analysis of variance was used for statistical analysis.

RESULTS: There is the difference in peripheral blood flow among before, during, and after immersing the legs into artificial CO2-rich water using Bicarbonated JesC CREA BC-2000 (p < 0.001).

CONCLUSION: Bicarbonated JesC CREA BC-2000 may be used as the device to produce an artificial CO2-rich water bath that may affect peripheral blood flow in healthy volunteers.

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