The Risk Factors of Bacterial Meningitis in Late-Onset Neonatal Sepsis
DOI:
https://doi.org/10.3889/oamjms.2021.6706Keywords:
Bacterial meningitis, Late-onset neonatal sepsis, Risk factorsAbstract
BACKGROUND: Neonatal bacterial meningitis has a significant contribution on neonatal morbidity and mortality. It is the most common complication of late-onset neonatal sepsis. An understanding of the risk factors for bacterial meningitis in late-onset neonatal sepsis is required to provide comprehensive management.
AIM: To identify the risk factors of bacterial meningitis in late-onset neonatal sepsis.
METHODS: This is an analytical study with a case–control design, conducted in May 2019-February 2021, involving neonates aged 4–28 days who suffered from late-onset neonatal sepsis in Level II and III Neonatal Care Unit, Sanglah General Hospital Denpasar. Statistical analysis was performed using Chi-square and logistic regression.
RESULTS: A total of 54 patients were analyzed in this study. The mean age of subjects with neonatal bacterial meningitis was 13 days and the majority of them were male (51.9%). The risk factor of bacterial meningitis in late-onset neonatal sepsis was gestational age <37 weeks with odds ratio 4.22 (95% confidence interval 1.28–13.86, p = 0.01). There was no significant association of birth weight <2500 g, neonatal asphyxia, and invasive procedure on neonatal bacterial meningitis.
CONCLUSION: Gestational age <37 weeks is a risk factor for bacterial meningitis in late-onset neonatal sepsis.Downloads
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Copyright (c) 2020 Ni Made Reditya Noviyani, I Made Kardana, Dewi Sutriani Mahalini, Ida Bagus Gede Suparyatha, Ketut Ariawati, Gusti Ayu Putu Nilawati, Made Sukmawati (Author)
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