Remineralization potential and mechanical evaluation of a bioactive glass containing composite (An ex vivo study)


  • Nouran Hussein Dental Materials Department, Faculty of Dentistry, British University in Egypt (BUE), Cairo, Egypt
  • Dina A. El Refai Department of Biomaterials, Faculty of Dentistry, Ain-Shams University, Cairo, Egypt
  • Ghada Atef Alian Department of Biomaterials, Faculty of Dentistry, Ain-Shams University, Cairo, Egypt



Resin composites, Remineralization, ACTIVA, Ion release, Wear, Micro-shear bond



AIM: The aim of this study was to compare the remineralization ability, ion release, microshear bond strength and wear resistance of a claimed bioactive restorative material (ACTIVA BioACTIVE Restorative, Pulpdent Corporation, Watertown, USA) with the conventional resin composite (​Filtek Z350 XT, 3M ESPE Elipar, Germany).

MATERIALS AND METHODS: The remineralization ability was evaluated after 28 days using Energy Dispersive X-Ray (EDX) analysis. Ion release was investigated at three-time intervals: 1, 14 and 28 days. Calcium and phosphate ions release were determined by using ion chromatography system. Microshear bond strength was assessed using Universal Testing Machine. A wear test was conducted using a dual axis chewing simulator.

RESULTS: ACTIVA™ was found to induce remineralization to the demineralized dentin. Results revealed that ACTIVA™ released Ca2+ and PO4-3 ions, whilst Filtek Z350 XT did not. Concerning microshear bond strength ACTIVA™ without adhesive application showed unacceptable failure. Regarding wear resistance there was no statistically significant difference between them.

CONCLUSION: ACTIVA™ bioactive restorative material seems promising bioactive restorative materials. Clinical trials are recommended to compare clinical performance of ACTIVA™ with the other restorative materials.


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How to Cite

Hussein N, El Refai DA, Atef Alian G. Remineralization potential and mechanical evaluation of a bioactive glass containing composite (An ex vivo study). Open Access Maced J Med Sci [Internet]. 2021 Sep. 3 [cited 2023 Sep. 27];9(D):179-85. Available from: