Epidemiology of Gastrointestinal Disease among Children and Adolescents in Kazakhstan: 2012–2019

Alikhan  Zhaksylyk; Ardak Nurbakyt; Andrej  Grjibovski; Galina  Kaussova; Myrzatai Buleshov

doi:10.3889/oamjms.2021.6931

Authors

Alikhan Zhaksylyk Department of Scientific and Clinical Work, Doctoral and Master’s Programs, Doctoral Student, South Kazakhstan Medical Academy, Kazakhstan’s Medical University, Almaty, Kazakhstan
Ardak Nurbakyt Department of Epidemiology, Evidence-Based Medicine and Biostatistics, Kazakhstan’s Medical University, Almaty, Kazakhstan
Andrej Grjibovski Central Research Laboratory, Northern State Medical University, Ministry of Health of the Russian Federation, Arkhangelsk, Russia
Galina Kaussova Department of Public Health and Social Sciences, Kazakhstan’s Medical University, Almaty, Kazakhstan
Myrzatai Buleshov Department of Preventive Medicine and Dental Disciplines, Khoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan

DOI:

https://doi.org/10.3889/oamjms.2021.6931

Keywords:

Epidemiology, Gastrointestinal diseases, Children, Adolescents

Abstract

BACKGROUND: Gastrointestinal diseases are important trigger of public health concern in pediatric population. Non treated pathologies led to chronic inflammatory processes in adulthood.

AIM: With respect to the lack of international studies on epidemiology of gastrointestinal disease in pediatric population, this study was aimed at analysis of national and local incidence rates of gastrointestinal disorders among children and adolescents in Kazakhstan over the period from 2012 to 2019.

METHODS: This was a retrospective cross-sectional study located on South part of Kazakhstan and based on the data obtained from the Republican Center for Health Development – the major data source on the country’s health statistics. From this, we extracted information on children (0–14 years) and adolescents (15–17 years) with gastrointestinal disease (K00-K95 International Classification of Diseases, Revision 10 codes). We calculated incidence rates for the whole country and Turkestan province.

RESULTS: The national incidence of pediatric disease was characterized by relative stability, and was 7760.4 per 100,000 population in 2017. The incidence of peptic ulcers and gallbladder disease in adolescents substantially exceeded that in children. At provincial level the incidence of gastritis/duodenitis and peptic ulcers was gradually declining, while that of gallbladder disease was subjected to growth over the past years. Adolescents had higher rates of gastrointestinal disease both at national and provincial levels.

CONCLUSION: The analysis of national and local incidence rates of gastrointestinal disorders among children and adolescents in Kazakhstan showed that more studies are needed to obtain in-depth understanding of risk factors associated with gastrointestinal disease in child and adolescent population of Kazakhstan, including the prevalence of Helicobacter pylori infection. Besides, a national registry on pediatric gastrointestinal disease should be envisaged to overcome the lack of essential data.

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References

Ashorn M. Gastrointestinal diseases in the paediatric age groups in Europe: Epidemiology and impact on healthcare. Aliment Pharmacol Ther 2003;18(Suppl 3):80-3. http://doi.org/10.1046/j.0953-0673.2003.01730.x PMid:14531747 DOI: https://doi.org/10.1046/j.0953-0673.2003.01730.x

Islek A, Yilmaz A, Elpek GO, Erin N. Childhood chronic gastritis and duodenitis: Role of altered sensory neuromediators. World J Gastroenterol 2016;22(37):8349-60. http://doi.org/10.3748/wjg.v22.i37.8349 PMid:27729741 DOI: https://doi.org/10.3748/wjg.v22.i37.8349

Alper A, Hardee S, Rojas-Velasquez D, Escalera S, Morotti RA, Pashankar DS. Prevalence and clinical, endoscopic, and pathological features of duodenitis in children. J Pediatr Gastroenterol Nutr. 2016;62(2):314-6. http://doi.org/10.1097/MPG.0000000000000942 PMid:26252915 DOI: https://doi.org/10.1097/MPG.0000000000000942

Lee EJ, Lee YJ, Park JH. Usefulness of ultrasonography in the diagnosis of peptic ulcer disease in children. Pediatr Gastroenterol Hepatol Nutr. 2019;22(1):57-62. http://doi.org/10.5223/pghn.2019.22.1.57 PMid:30671374 DOI: https://doi.org/10.5223/pghn.2019.22.1.57

Walker SK, Maki AC, Cannon RM, Foley DS, Wilson KM, Galganski LA, et al. Etiology and incidence of pediatric gallbladder disease. Surg (United States). 2013;154(4):927-33. http://doi.org/10.1016/j.surg.2013.04.040 PMid:24074432 DOI: https://doi.org/10.1016/j.surg.2013.04.040

Morinville VD, Husain SZ, Bai H, Barth B, Alhosh R, Durie PR, et al. Definitions of pediatric pancreatitis and survey of present clinical practices. J Pediatr Gastroenterol Nutr. 2012;55(3):261-5. http://doi.org/10.1097/MPG.0b013e31824f1516 PMid:22357117 DOI: https://doi.org/10.1097/MPG.0b013e31824f1516

Rosen MJ, Dhawan A, Saeed SA. Inflammatory bowel disease in children and adolescents. JAMA Pediatr. 2015;169:1053-60. http://doi.org/10.1001/jamapediatrics.2015.1982 PMid:26414706 DOI: https://doi.org/10.1001/jamapediatrics.2015.1982

Dauletyarova M, Semenova Y, Kaylubaeva G, Manabaeva G, Khismetova Z, Akilzhanova Z, et al. Are women of East Kazakhstan satisfied with the quality of maternity care? Implementing the WHO tool to assess the quality of hospital services. Iran J Public Health. 2016;45(6):729-38. PMid:27648415

Sierra D, Wood M, Kolli S, Felipez LM. Pediatric gastritis, gastropathy, and peptic ulcer disease. Pediatr Rev. 2018;39(11):542-9. http://doi.org/10.1542/pir.2017-0234 PMid:30385583 DOI: https://doi.org/10.1542/pir.2017-0234

Sipponen P, Maaroos HI. Chronic gastritis. Scand J Gastroenterol. 2015;50(6):657-67. http://doi.org/10.3109/00365521.2015.1019918 PMid:25901896 DOI: https://doi.org/10.3109/00365521.2015.1019918

Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: Cholelithiasis and cancer. Gut Liver. 2012;6(2):172-87. http://doi.org/10.5009/gnl.2012.6.2.172 PMid:22570746 DOI: https://doi.org/10.5009/gnl.2012.6.2.172

Ciccone S, Guerrini G, Lacorte D, Govoni MR. PP40 Acute pancreatitis in children and adolescents. Dig Liver Dis. 2011;43:S426. DOI: https://doi.org/10.1016/S1590-8658(11)60683-X

Raman M, Milestone AN, Walters JR, Har AL, Ghosh S. Vitamin D and gastrointestinal diseases: Inflammatory bowel disease and colorectal cancer. Ther Adv Gastroenterol. 2011;4(1):49-62. http://doi.org/10.1177/1756283X10377820 PMid:21317994 DOI: https://doi.org/10.1177/1756283X10377820

Haimi M. Nutritional deficiencies in the pediatric age group in a multicultural developed country, Israel. World J Clin Cases. 2014;2(5):120-5. http://doi.org/10.12998/wjcc.v2.i5.120 PMid:24868510 DOI: https://doi.org/10.12998/wjcc.v2.i5.120

Abu-El-Haija M, Uc A, Werlin SL, Freeman AJ, Georgieva M, Jojkić-Pavkov D, et al. Nutritional considerations in pediatric pancreatitis: A position paper from the NASPHAN pancreas committee and ESPHAN cystic fibrosis/pancreas working group. J Pediatr Gastroenterol Nutr. 2018;67(1):131-43. http://doi.org/10.1097/MPG.0000000000002023 PMid:29927872 DOI: https://doi.org/10.1097/MPG.0000000000002023

Gromova O, Doschanova A, Lokshin V, Tuletova A, Grebennikova G, Daniyarova L, et al. Vitamin D deficiency in Kazakhstan: Cross-sectional study. J Steroid Biochem Mol Biol. 2020;199:105565. http://doi.org/10.1016/j.jsbmb.2019.105565 PMid:31812522 DOI: https://doi.org/10.1016/j.jsbmb.2019.105565

Yelissinova N, Grjibovski AM, Yelissinova A, Rakhypbekov T, Semenova Y, Smailova Z, et al. Sociodemographic factors associated with infant abandonment in maternity hospitals in Kazakhstan: A case-control study. Public Health. 2015;129(7):1010-3. http://doi.org/10.1016/j.puhe.2015.04.009 PMid:25986952 DOI: https://doi.org/10.1016/j.puhe.2015.04.009