Lipid Accumulation Product as an Index for Visceral Obesity and Cardiovascular Risk among a Sample of Obese Egyptian Women

Nayera E. Hassan; Sahar A. El-Masry; Gamila S. M. El-Saeed; Mohamed S. El Hussieny

doi:10.3889/oamjms.2021.7027

Authors

Nayera E. Hassan Department of Biological Anthropology, Medical Research Division, National Research Centre, Dokki, Giza, Egypt
Sahar A. El-Masry Department of Biological Anthropology, Medical Research Division, National Research Centre, Dokki, Giza, Egypt https://orcid.org/0000-0002-1416-0633
Gamila S. M. El-Saeed Department of Medical Biochemistry, Medical Research Division, National Research Centre, Cairo, Egypt
Mohamed S. El Hussieny Department of Biological Anthropology, Medical Research Division, National Research Centre, Dokki, Giza, Egypt

DOI:

https://doi.org/10.3889/oamjms.2021.7027

Keywords:

Lipid accumulation product, Visceral fat, Cardiovascular risk factors, Egyptian women

Abstract

Background:Lipid accumulation product (LAP) is one of the indices that can demonstrate cardiovascularrisk factors according to international studies. Aim: To evaluate relationship between LAP, visceral obesity and different cardio vascular risk factors among sample of obese Egyptian Women. Methods: A retrospective cross-sectional observational study included 350 obese Egyptian women; aged 25- 55 years. They were subjected to blood pressure and anthropometric assessment (weight, height and waist circumference), abdominal ultrasound (visceral fat) and laboratory tests (fasting blood sugar and lipid profile).Results: The majority of the participated women had wide WC (88.9%) and increased visceral fat (80.6%). Hyperglycemia was present among (47.4%), hypertension among 42.6%, high triglycerides among 26.6% and low HDL among 44.3%. The odds of obtaining LAP >80.74 cm.mmol/L (4^th quartile) is 2.7 times higher in individuals with hypertension(BP > 130/85),and 6.79 times higher in individuals with visceral fat ≥ 5 cm. Depending on the visceral fat as a standard for classification of visceral obesity (>5 cm for women), revealed that the AUCs of LAP was 0.752 (95% CI 0.697–0.806) in women. The cutoff point of LAP;for prediction of visceral obesity among Egyptian women, was 61.69; using ROC analysis; with sensitivity 68% and specificity 75% and PPV/NPV 1.05 and accuracy 71.5% .Conclusion: LAP index had significant correlations with visceral obesity and hypertension. The cutoff point of LAP 61.69 can be used to predict visceral obesity among Egyptian women.

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