The Estimate of Interferon-inducible Protein-10 and Interferon-γ in Hemodialysis Patients with Chronic HCV

Mahmood Abdujabar Altobje; Zeyad Thanoon Al-Rrassam

doi:10.3889/oamjms.2021.7030

Authors

Mahmood Abdujabar Altobje Department of Biology, College of Science, University of Mosul, Mosul, Iraq
Zeyad Thanoon Al-Rrassam Department of Biophysics, College of Science, University of Mosul, Mosul, Iraq

DOI:

https://doi.org/10.3889/oamjms.2021.7030

Keywords:

Alkaline phosphatase, CXCL-10, HCV, Hemodialysis, Interferon

Abstract

BACKGROUND: Due to the rise in the number of deaths, the hepatitis C virus remains a public health issue worldwide. During the recovery period, cytokines are known as indicators of chronic liver infection.

AIM: In this study, immunological parameters were measured and calculated in chronic hemodialysis patients after more than 6 months of drug administration.

METHODS: We have picked 60 patients with hemodialysis who are anti-HCV positive. ELISA and the calculation of alkaline phosphatase (ALP) were used to evaluate IP-10 and IFN-γ.

RESULTS: A substantial association between variables and infected cases was found. No worth was considered for genders or age categories.

CONCLUSIONS: The serum IP-10 level can be a warning primarily for patients who have taken a variety of prescriptions intermittently. In both the RPT and RST cohorts, IFN-γ serum levels are usually elevated. Serum level ALP is not a particular chronic HCV predictor.

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