Concordance between Triglyceride Glucose Index and Admission Insulin Resistance Index in Non-diabetic Subjects of Acute Coronary Syndrome

Authors

  • Andi Irham Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Husaini Umar Department of Internal Medicine, Division of Endocrine Metabolic and Diabetes, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Fabiola Maureen Shinta Adam Department of Internal Medicine, Division of Endocrine Metabolic and Diabetes, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Idar Mappangara Department of Internal Medicine, Division of Cardiology and Vascular Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Syakib Bakri Department of Internal Medicine, Division of Nephrology and Hypertension, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Risna Halim Department of Internal Medicine, Division of Tropical Medicine and Infectious Disease, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Alfian Zainuddin Department of Biostatistics, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2021.7075

Keywords:

Insulin resistance, Triglyceride glucose index, Admission insulin resistance index, Non-diabetic of acute coronary syndrome

Abstract

BACKGROUND: Acute coronary syndrome (ACS) is the leading cause of death in the world and is closely related to insulin resistance (IR). The examination of the triglyceride glucose (TyG) Index and admission IR index (AIRI) can be an alternative examination to assess IR.

AIM: The aim of the study was to analyze the concordance between the TyG index and AIRI in assessing IR in nondiabetic subjects of ACS.

METHODS: This study was a cross-sectional study using secondary data from ACS patient medical records in Wahidin Sudirohusodo Hospital Makassar from September 2020 until April 2021. An examination of RBG, TyG, and fasting insulin was performed. The statistical test results were considered significant if the p < 0.05.

RESULTS: This study included 67 subjects, of which 54 were male and 13 were female, there were 24 people aged <50 years, 43 people aged 50 years old, with a mean of 55.15 ± 12.71 years, a diagnosis of ST-elevation myocardial infarction (STEMI) 25 people, non STEMI 34 people and unstable angina pectoris 8 people, p < 0.05. The receiver operating characteristic curve showed that the cut-off value of the TyG index in predicting AIRI was 3141, with a sensitivity of 88.98% and specificity of 59.09%. The OR value revealed that subjects with a TyG index of >9.06 indicated an 11-time greater risk for IR than subjects with a TyG index ≤9.06.

CONCLUSIONS: There was a significant concordance between the TyG index and the AIRI in non-diabetic acute coronary syndrome patient.

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Published

2021-10-01

How to Cite

1.
Irham A, Umar H, Adam FMS, Mappangara I, Bakri S, Halim R, Zainuddin A. Concordance between Triglyceride Glucose Index and Admission Insulin Resistance Index in Non-diabetic Subjects of Acute Coronary Syndrome. Open Access Maced J Med Sci [Internet]. 2021 Oct. 1 [cited 2022 May 21];9(B):1044-7. Available from: https://oamjms.eu/index.php/mjms/article/view/7075

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