Interleukin-6 as Immune System and Inflammation Biomarker on the Response of Basic Pencak Silat Exercise in Perguruan Pencak Silat Perisai Diri, Bojonegoro


  • Roy Irawan Department of Sport Science, Faculty of Sport Science, Universitas Negeri Surabaya, Surabaya, East Java, Indonesia image/svg+xml
  • Trias Mahmudiono Department of Nutrition, Faculty of Public Health, Universitas Airlangga, Surabaya, East Java, Indonesia
  • Tri Martiana Departement of Occupational Safety and Health, Faculty of Public Health, Universitas Airlangga, Surabaya, East Java, Indonesia



Immune system, Inflammation biomarker, Exercise, Martial art, Health and well-being


BACKGROUND: Pencak Silat is a self-defense exercise originated from Indonesia and categorized as a high-intensity exercise.

AIM: This research was intended to identify the acute response of Pencak Silat basic exercise toward interleukin-6 (IL-6) as an immune system biomarker on students of Perguruan Pencak Silat Perisai Diri Tulungrejo, Bojonegoro.

METHODS: A number of 26 students (10 boys and 16 girls) of Perguruan Pencak Silat Tulungrejo, Bojonegoro, were participated in this study. The students did the 2 h Perguruan Pencak Silat Perisai Diri, Bojonegoro, training program with 75–85% intensity. The IL-6 serum was measured using ELISA method.

RESULTS: The result of this study showed that the IL-6 serum level in post-2 (12 h after training) (6.2981 pg/mL) was higher compared with the IL-6 serum level in post-1 (shortly after training) (6.11981 pg/mL) and before training (4.5146 pg/mL). The result also showed that there was a significant difference of IL-6 levels between pre-training and after training.

CONCLUSION: This study concluded that the basic exercise performed by the new students of Perguruan Pencak Silat Perisai Diri increased IL-6 serum level.


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How to Cite

Irawan R, Mahmudiono T, Martiana T. Interleukin-6 as Immune System and Inflammation Biomarker on the Response of Basic Pencak Silat Exercise in Perguruan Pencak Silat Perisai Diri, Bojonegoro. Open Access Maced J Med Sci [Internet]. 2021 Nov. 12 [cited 2022 Aug. 15];9(T6):179-83. Available from:

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