The Study of Drug-Related Problems in Pediatric Inpatients Utilizing Antibiotics in Universitas Sumatera Utara Hospital Medan, Indonesia


  • Embun Suci Nasution Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
  • Rasmadin Muchtar Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia image/svg+xml
  • Rony Abdi Syahputra Department of Pharmacology



Drug-related problems, Antibiotic, Pediatric hospitalized patient, Medical record


BACKGROUND: Drug-related problems (DRPs) and errors occur frequently in general health and pediatric care due to several reasons.

AIM: This study aims to determine the DRPs incidence in pediatric inpatients utilizing antibiotics in Universitas Sumatera Utara Hospital, Medan, Indonesia.

MATERIALS AND METHODS: It was carried out in May–July 2019 using a retrospective cross-sectional method and the data obtained from June to December 2018.

RESULTS: In the aforementioned hospital, the medical records of patients were 575 among which 135 (23.47%) met the inclusion criteria and the males, 84 (62.22%) were higher than females. Furthermore, majority of them, 55 (40.74%) were 5–11 years old, and 86 (63.70%) had a maximum stay length of ≥5 days. There were 73 DRPs events in 37 patients, namely, 46 (63.01%) low doses, 22 (30.14%) overdoses, 2 (2.74%) side effects of drugs, and 3 (4.11%) drug interactions. The most experienced antibiotic DRPs were in cefotaxime 14 (19.17%) and the most diagnosed was in appendicitis 14 (10.37%) utilization.

CONCLUSION: There were antibiotic DRPs in pediatric inpatients in Universitas Sumatera Utara Hospital, Medan.


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How to Cite

Nasution ES, Muchtar R, Syahputra RA. The Study of Drug-Related Problems in Pediatric Inpatients Utilizing Antibiotics in Universitas Sumatera Utara Hospital Medan, Indonesia. Open Access Maced J Med Sci [Internet]. 2022 Jan. 3 [cited 2023 Mar. 22];10(A):187-91. Available from:

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