Profile of Sepsis Patients Treated in Intensive Care Unit of Sanglah Hospital Denpasar
DOI:
https://doi.org/10.3889/oamjms.2021.7690Keywords:
Sepsis, qSOFA score, Comorbid, Ventilator, Mortality, DenpasarAbstract
BACKGROUND: Primary data regarding sepsis patients in Indonesia, especially in Denpasar, are still limited in number in reporting. The lack of information about sepsis made the authors interested in conducting this study.
AIM: The aim of the study was to obtain more in-depth information about the profile of sepsis patients treated in Sanglah Hospital, Denpasar.
MATERIALS AND METHODS: This was a cross-sectional descriptive research. Target population in this study are data on patient registers that are included in the inclusion criteria from June 1, 2019 to June 30, 2021, at intensive care unit Sanglah Hospital, Denpasar. The variables in this study included: Demographic conditions such as age, gender, and address, qSOFA score, comorbidities, ventilator, and patient’s outcome (survival or non-survival).
RESULTS: A total samples were 173 patients. The average age of patients in this study was 54 years old with 56.6% male and 32.9% lived in Denpasar. Patients suspected of having early sepsis had a qSOFA 0 score of 35.3%, qSOFA 1 was 33.5%, qSOFA 2 was 23.7%, and qSOFA 3 was 7.5%. Patients with sepsis and suspected sepsis with comorbidities were 96% and 79.8% of patients were on a ventilator. The mortality rate in this study was 67.1%.
CONCLUSION: These primary data hopefully become references for the future research.Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Kempker JA, Martin GS. The changing epidemiology and definitions of sepsis. Clin Chest Med. 2016;37(2):165-79. https://doi.org/10.1016/j.ccm.2016.01.002 PMid:27229635
Irvan I, Febyan F, Suparto S. Sepsis dan tata laksana berdasar guideline terbaru. J Anestesiol Indones. 2018;10(1):62.
Mira M. Gambaran Nilai Monitoring Hemodinamik Non Invasif Pada Pasien Sepsis Di Ruang Terapi Intensif Care. Mahakam Nurs J. 2019;2(6):158.
Martin-Loeches I, Wunderink RG, Nanchal R, Lefrant JY, Kapadia F, Sakr Y, et al. Determinants of time to death in hospital in critically ill patients around the world. Intensive Care Med. 2016;42(9):1454-60. https://doi.org/10.1007/s00134-016-4479-0 PMid:27518322
Villar J, Blanco J, Zhang H, Slutsky AS. Ventilator-induced lung injury and sepsis: Two sides of the same coin. Minerva Anestesiol. 2011;77(6):647-53. PMid:21617628
Kaukonen KM, Bailey M, Pilcher D, Cooper DJ, Bellomo R. Systemic Inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015;372(17):1629-38. https://doi.org/10.1056/NEJMoa1415236 PMid:25776936
Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, et al. Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014. JAMA. 2017;318(13):1241-9. PMid:28903154
Moore LJ, Moore FA, Jones SL, Xu J, Bass BL. Sepsis in general surgery: A deadly complication. Am J Surg. 2009;198(6):868-74. https://doi.org/10.1016/j.amjsurg.2009.05.025 PMid:19969144
Moore LJ, Moore FA, Todd SR, Jones SL, Turner KL, Bass BL. Sepsis in general surgery: The 2005-2007 national surgical quality improvement program perspective. Arch Surg. 2010;145(7):695-700. https://doi.org/10.1001/archsurg.2010.107 PMid:20644134
Tambajong RN, Lalenoh DC, Kumaat L. Profil Penderita Sepsis di ICU RSUP Prof. Dr. R. D. Kandou Manado Periode Desember 2014-November 2015. E-Clinic. 2016;4(1):11011. https://doi.org/10.35790/ecl.v4i1.11011
Purwanti OS, Sinuraya RK, Pradipta IS, Abdulah R. Analisis minimalisasi biaya antibiotik pasien sepsis salah satu rumah sakit kota Bandung. J Farm Klin Indones. 2013;2(1):18-27.
Causes and outcomes of sepsis in Southeast Asia: A multinational multicentre cross-sectional study. Lancet Glob Health. 2017;5(2):e157-67. https://doi.org/10.1016/S2214-109X(17)30007-4 PMid:28104185
Angele MK, Pratschke S, Hubbard WJ, Chaudry IH. Gender differences in sepsis: Cardiovascular and immunological aspects. Virulence. 2014;5(1):12-9. https://doi.org/10.4161/viru.26982 PMid:24193307
Beery TA. Sex differences in infection and sepsis. Crit Care Nurs Clin North Am. 2013;15(1):55-62. https://doi.org/10.1016/s0899-5885(02)00028-x PMid:12597040
Starr ME, Saito H. Sepsis in old age: Review of human and animal studies. Aging Dis. 2014;5(2):126-36. https://doi.org/10.14336/AD.2014.0500126 PMid:24729938
Usman OA, Usman AA, Ward MA. Comparison of SIRS, qSOFA, and NEWS for the early identification of sepsis in the emergency department. Am J Emerg Med. 2019;37(8):1490-7. https://doi.org/10.1016/j.ajem.2018.10.058 PMid:30470600
Corfield AR, Lees F, Zealley I, Houston G, Dickie S, Ward K, et al. Utility of a single early warning score in patients with sepsis in the emergency department. Emerg Med J. 2014;31(6):482-7. https://doi.org/10.1136/emermed-2012-202186 PMid:23475607
Simpson SQ. New sepsis criteria: A change we should not make. Chest. 2016;149:1117-8. https://doi.org/10.1016/j.chest.2016.02.653 PMid:26927525
Çıldır E, Bulut M, Akalın H, Kocabaş E, Ocakoğlu G, Aydın ŞA. Evaluation of the modified MEDS, MEWS score and Charlson comorbidity index in patients with community acquired sepsis in the emergency department. Intern Emerg Med. 2013;8(3):255-60. https://doi.org/10.1007/s11739-012-0890-x PMid:23250543
Kamilla M. Faktor Risiko Sepsis dan Pengaruhnya Terhadap Tingkat Keparahan Pasien Sepsis di Bangsal Infeksi Penyakit dalam RSUD dr. Soedono Madiun. Indonesia: Univesrsitas Islam Indonesia; 2019.
Fang WF, Fang YT, Huang CH, Chen YM, Chang YC, Lin CY, et al. Risk factors and associated outcomes of ventilator-associated events developed in 28 days among sepsis patients admitted to intensive care unit. Sci Rep. 2020;10(1):12702. https://doi.org/10.1038/s41598-020-69731-3 PMid:32728165
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2020 Merry Merry, I Gusti Agung Gede Utara Hartawan, I Wayan Aryabiantara, Dewa Ayu Mas Shintya Dewi (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)
