Reference Range of Complete Blood Count in Healthy Term Newborns 1 Week after Birth

Harapan Parlindungan Ringoringo

doi:10.3889/oamjms.2021.7781

Authors

Harapan Parlindungan Ringoringo Department of Child Health, Faculty of Medicine, Lambung Mangkurat University, RSD Idaman, Banjarbaru, Indonesia https://orcid.org/0000-0001-5678-0059

DOI:

https://doi.org/10.3889/oamjms.2021.7781

Keywords:

Reference range, Complete blood count, Reticulocyte, Term newborns, MeSH

Abstract

BACKGROUND: Determination of the complete blood count (CBC) and reticulocyte reference range helps diagnose a disease related to changes in erythrocyte indices, white blood count, platelets, and reticulocytes, especially in newborns.

AIM: The aim study is to establish a reference range for CBC and reticulocyte in healthy term newborns 1 week after birth.

MATERIAL AND METHODS: The study method is prospective analyses of CBC and reticulocyte in term newborns within 1 week after birth. Inclusion criteria are term newborn (gestational age 37–42 weeks) with good tone, breathing, or crying immediately, do not have resuscitation, and the birth weight is ≥2500 g.

RESULTS: Two hundred and seventy-seven term newborns met the inclusion criteria. There were 145 (52.35%) male infants and 132 (47.65%) female infants. The reference range of newborns for hemoglobin (Hb) at P2.5–P97.5, P3–P97, P5–P95, and mean ± 2 standard deviation (SD) was 11.70–19.60 g/dL, 11.90–19.57 g/dL, 12.20–19.20 g/dL, and 11.35–19.63 g/dL, respectively. In addition, reference range of male newborns for Hb at P2.5–P97.5, P3–P97, P5–P95, and mean ± 2SD was 12.20–20.14 g/dL, 12.28–19.91 g/dL, 12.63–19.38 g/dL, and 11.47–20.15 g/dL, respectively. The reference range of female newborns for Hb at P2.5–P97.5, P3–P97, P5–P95, and mean ± 2 SD was 11.37–19.20 g/dL, 11.50–19.20 g/dL, 11.80–19.20 g/dL, and 11.37–18.93 g/dL, respectively.

CONCLUSION: The reference range of CBC and reticulocyte for healthy term newborns, male newborns, and female newborns in this study can be used as a benchmark.

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