Social Nervous Exercise Intervention and Its Association with Fasting Blood Glucose on Diabetes Mellitus Gestational
Keywords:Gestational diabetes mellitus, Intervention, Social nervous exercise, Fasting blood glucose, Indonesia
BACKGROUND: Gestational diabetes mellitus (GDM) has been identified as a major complication of pregnancies and has remained a major cause of perinatal morbidity and mortality, in both mother and child. Exercise can be used as a strategy to reduce hyperglycemia experienced during GDM. Regular exercise is important for a healthy pregnancy and can lower the risk of developing GDM. For women with GDM. Exercise is safe and can affect the pregnancy outcomes beneficially. The role of exercise about increases skeletal muscle glucose uptake and minimizing hyperglycemia. Social nervous (SaSo) exercise is a moderate-intensity exercise intervention that plays a role in controlling blood glucose through autonomic nervous stimulation so that it has an effect on glucose homeostasis. Social nervous exercise can stimulate the parasympathetic or myelinated vagus nerves. The social nerve or the social nervous system is the vagus nerve nc-X which is supported by cranial nerves, namely, nerves V, VII, IX, and XI centered in the nucleus ambiguous.
AIM: The aim of the study is to determine the impact of a social nervous (SaSo) exercise training program consisting of warm-up, core (prayer movements), and cooling exercises on glucose homeostasis parameters in pregnant women diagnosed with GDM.
METHODS: Thirty-seven pregnant women diagnosed with GDM at 24–28 weeks of gestation were allocated into two groups, thats the experimental group (n=19) with the SaSo program being regularly monitored and the control group (n=18) receiving only standard antenatal care for GDM. The Saso program started from the time diabetes was diagnosed until 6 weeks of intervention. Interventions were performed twice per week and sessions lasted 40–45 min.
RESULTS: The baseline results for the experimental and control groups were homogeneous, without differences in the baseline variables (p > 0.05). Social nervous exercise the experimental group significantly reduced fasting blood glucose levels (p < 0.001) compared to the control group.CONCLUSIONS: A social nervous exercise program has a beneficial effect on fasting blood glucose levels in late pregnancy.
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Daniel JA, Nzeribe E, Udoaku AA. Aerobic training impacts on blood cholesterol of women with gestational diabetes. Open J Obstet Gynecol. 2021;11:474-83.
Dipla K, Zafeiridis A, Mintziori G, Boutou AK, Goulis DG, Hackney AC. Exercise as a therapeutic intervention in gestational diabetes mellitus. Endocrines. 2021;2(2):65-78. https://doi.org/10.3390/endocrines2020007 PMid:33870263
Dirar AM, Doupis J. Gestational diabetes from A to Z. World J Diabetes. 2017;8(12):489-511. https://doi.org/10.4239/wjd.v8.i12.489 PMid:29290922
Amiri N, Metab D, Amiri FN, Sepidarkish M, Shirvani MA, Habibipour P. The effect of exercise on the prevention of gestational diabetes in obese and overweight pregnant women: A systematic review and metaanalysis. Diabetol Metab Syndr. 2019;11(1):1-14. https://doi.org/10.1186/s13098-019-0470-6
Koo BK, Lee JH, Kim J, Jang EJ, Lee CH. Prevalence of gestational diabetes mellitus in Korea: A national health insurance database study. PLoS One. 2016;11(4):e0153107. https://doi.org/10.1371/journal.pone.0153107 PMid:27046149
Birmingham K, Gradinaru V, Anikeeva P, Grill WM, Pikov V, Mclaughlin B, et al. Bioelectronic medicines: A research roadmap. Nat Rev Drug Discov. 2014;13(6):399-400. https://doi.org/10.1038/nrd4351 PMid:24875080
And AG, Georgiou P. Review of the role of the nervous system in glucose homoeostasis and future perspectives towards the management of diabetes. Bioelectron Med. 2018;4:9. https://doi.org/10.1186/s42234-018-0009-4 PMid:32232085
Chandra R, Liddle RA. Recent advances in the regulation of pancreatic secretion. Curr Opin Gastroenterol. 2014;30(5):490-4. https://doi.org/10.1097/MOG.0000000000000099 PMid:25003603
Couck MD, Mravec B, Gidron Y. You may need the vagus nerve to understand pathophysiology and to treat diseases. Clin Sci (Lond). 2012;122(7):323-8. https://doi.org/10.1042/CS20110299 PMid:22150254
Carnagarin R, Matthews VB, Herat LY, Ho JK, Schlaich MP. Autonomic regulation of glucose homeostasis: A specific role for sympathetic nervous system activation. Curr Diab Rep. 2018;18(11):107. https://doi.org/10.1007/s11892-018-1069-2 PMid:30232652
Porges SW. The polyvagal theory: Phylogenetic substrates of a social nervous system. Int J Psychophysiol [Internet]. 2001;42(2):123-46. https://doi.org/10.1016/S0167-8760(01)00162-3. PMid:11587772
Porges SW. The polyvagal theory: New insights into adaptive reactions of the autonomic nervous system. Cleve Clin J Med. 2009;76 Suppl 2:S86-90. https://doi.org/10.3949/ccjm.76.s2.17 PMid:19376991
Kaneto A, Miki E, Kosaka K. Effects of Vagal Stimulation on Glucagon and Insulin Secretion; 2015.
Porges SW. Comprehensive psychoneuroendocrinology polyvagal theory: A biobehavioral journey to sociality. Compr Psychoneuroendocrinol. 2021;7:100069. https://doi.org/10.1016/j.cpnec.2021.100069 15. Sheen J, Wright JD, Goffman D, Kern-goldberger AR, Booker W, Ms ZS, et al. Maternal age and risk for adverse outcomes. Am J Obstet Gynecol. 2018;219(4):390.e1-15. https://doi.org/10.1016/j.ajog.2018.08.034
Braunthal S, Brateanu A. Hypertension in pregnancy: Pathophysiology and treatment. SAGE Open Med. 2019;7:2050312119843700. https://doi.org/10.1177/2050312119843700 PMid:31007914
Ramakrishnan U, Grant F, Goldenberg T, Zongrone A, Martorell R. Effect of women’s nutrition before and during early pregnancy on maternal and infant outcomes: A systematic review. Paediatr Perinat Epidemiol. 2012;26 Suppl 1:285-301. https://doi.org/10.1111/j.1365-3016.2012.01281.x PMid:22742616
Tian Y, Shen L, Wu J, Chen W, Yuan J, Yang H, et al. Parity and the risk of diabetes mellitus among Chinese women: A cross-sectional evidence from the tongji-dongfeng cohort study. PLoS One. 2014;9(8):e104810. https://doi.org/10.1371/journal.pone.0104810 PMid:25105792
Moosazadeh M, Asemi Z, Lankarani KB, Tabrizi R, Maharlouei N, Naghibzadeh-Tahami A, et al. Family history of diabetes and the risk of gestational diabetes mellitus in Iran : A systematic review and meta-analysis. Diabetes Metab Syndr. 2017;11 Suppl 1:S99-104. https://doi.org/10.1016/j.dsx.2016.12.016 PMid:28017634
Groof Z, Garashi G, Husain H, Owayed S, AlBader S, Mouhsen H, et al. Prevalence, risk factors, and fetomaternal outcomes of gestational diabetes mellitus in kuwait: A cross-sectional study. J Diabetes Res. 2019;2019:9136250. https://doi.org/10.1155/2019/9136250 PMid:30944829
Erem C, Kuzu UB, Deger O, Can G. Prevalence of gestational diabetes mellitus and associated risk factors in Turkish women: The Trabzon GDM study. Arch Med Sci. 2015;11(4):724-35. https://doi.org/10.5114/aoms.2015.53291 PMid:26322083
Levy A, Wiznitzer A, Holcberg G, Mazor M, Sheiner E. Family history of diabetes mellitus as an independent risk factor for macrosomia and cesarean delivery. J Matern Fetal Neonatal Med. 2010;23(2):148-52. https://doi.org/10.3109/14767050903156650 PMid:19637110
Flaa A, Aksnes TA, Kjeldsen SE, Eide I, Rostrup M. Increased sympathetic reactivity may predict insulin resistance: An 18-year follow-up study. Metabolism. 2008;57(10):1422-7. https://doi.org/10.1016/j.metabol.2008.05.012 PMid:18803948
Kanwisher N, Mcdermott J, Chun MM. The fusiform face area: A module in human extrastriate cortex specialized for face perception. J Neurosci. 1997;17(11):4302-11. https://doi.org/10.1523/JNEUROSCI.17-11-04302.1997 PMid:9151747
Shimazu T, Sudo M, Minokoshi Y, Takahashi A. Role of the hypothalamus in insulin-independent glucose uptake in peripheral tissues. Brain Res Bull. 1991;27(3–4):501–4. https://doi.org/10.1016/0361-9230(91)90149-E. PMid:1959052
Huang F, Dong J, Kong J, Wang H, Meng H, Spaeth RB, et al. Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance: A pilot randomized study. BMC Complement Altern Med. 2014;14:203. https://doi.org/10.1186/1472-6882-14-203 PMid:24968966
Li S, Zhai X, Rong P, Mccabe MF, Wang X, Zhao J, et al. Therapeutic effect of vagus nerve stimulation on depressive-like behavior, hyperglycemia and insulin receptor expression in zucker fatty rats. PLoS One. 2014;9(11):e112066. https://doi.org/10.1371/journal.pone.0112066 PMid:25365428
Alessio DA, Kieffer TJ, Taborsky GJ, Havel PJ. Activation of the parasympathetic nervous system is necessary for normal meal-induced insulin secretion in rhesus macaques. J Clin Endocrinol Metab. 2001;86(3):1253-9. https://doi.org/10.1210/jcem.86.3.7367 PMid:11238517
Wang C, Janese K, Yang H. ScienceDirect Exercise and its role in gestational diabetes mellitus. Chronic Dis Transl Med. 2016;2(4):208-14. https://doi.org/10.1016/j.cdtm.2016.11.006 PMid:29063044
Balaji PA, Varne SR. Physiological effects of yoga asanas and pranayama on metabolic parameters, maternal, and fetal outcome in gestational diabetes. J Physiol Pharm Pharmacol. 2017;7(7):724-8.
Kuntsevich V, Bushell WC, Theise ND. Mechanisms of yogic practices in health, aging, and disease. Mt Sinai J Med. 2010;77(5):559-69. https://doi.org/10.1002/msj.20214 PMid:20960557
Youngwanichsetha S, Phumdoung S, Ingkathawornwong T. The effects of mindfulness eating and yoga exercise on blood sugar levels of pregnant women with gestational diabetes mellitus. Appl Nurs Res. 2014;27(4):227-30. https://doi.org/10.1016/j.apnr.2014.02.002 PMid:24629718
Davenport MH, Mottola MF, McManus R, Gratton R. A walking intervention improves capillary glucose control in women with gestational diabetes mellitus: A pilot study. Appl Physiol Nutr Metab. 2008;33(3):511-7. https://doi.org/10.1139/H08-018 PMid:18461104
de Barros MC, Lopes MA, Francisco RP, Sapienza AD, Zugaib M. Resistance exercise and glycemic control in women with gestational diabetes mellitus. Am J Obstet Gynecol. 2010;203(6):556.e1-6. https://doi.org/10.1016/j.ajog.2010.07.015 PMid:20864072
Kokic IS, Ivanisevic M, Biolo G, Simunic B, Kokic T, Pisot R. Combination of a structured aerobic and resistance exercise improves glycaemic control in pregnant women diagnosed with gestational diabetes mellitus. A randomised controlled trial. Women and birth. 2018;31(4):e232-8. https://doi.org/10.1016/j.wombi.2017.10.004 PMid: 29055674
Garnæs KK, Mørkved S, Salvesen Ø, Moholdt T. Exercise training and weight gain in obese pregnant women: A randomized controlled trial (ETIP Trial). PLoS Med. 2016;13(7):e1002079. https://doi.org/10.1371/journal.pmed.1002079 PMid:27459375
Avery MD, Leon AS, Kopher RA. Effects of a partially home-based exercise program for women with gestational diabetes. Obstet Gynecol. 1997;89(1):10-5. https://doi.org/10.1016/s0029-7844(97)84256-1 PMid:8990428
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