Effect of Oral Nutritional Supplementation on National Institute of Health Stroke Scale in Acute Ischemic Stroke
DOI:
https://doi.org/10.3889/oamjms.2022.7974Keywords:
Oral nutritional supplementation, National institute of health stroke scale, Acute ischemic strokeAbstract
BACKGROUND: Approximately, 6-31% of nutritional deficits are present before the stroke and worsen during hospitalization. Besides affecting the patient’s physical and mental abilities, stroke can also cause a decrease in nutritional status, which has a major influence on the rate of death and disability. One intervention to overcome stroke patients’ nutritional problems is giving oral nutritional supplementation. The role of oral nutritional supplementation in stroke severity in patients with acute ischemic stroke has not yet been extensively studied.
AIM: This study aimed to evaluate the effect of oral nutritional supplementation on the National Institute of Health Stroke Scale (NIHSS) in patients with acute ischemic stroke.
METHODS: This was an experimental study with a pre- and post-study group method. Twenty-eight patients with acute ischemic stroke were referred to Adam Malik General Hospital, Medan, Indonesia, and were allocated randomly into two groups. Fourteen patients as control group received the normal hospital diet and 14 patients as intervention group received normal hospital diet plus oral nutritional supplementation for 7 days. The NIHSS scores were assessed on the first day and the eighth day after intervention in each group.
RESULTS: There were significant reductions in NIHSS scores between day 1 and day 8 in both groups (p < 0.001). The mean delta NIHSS scores were −2.28 ± 1.63 and −2.57 ± 1.98 in the intervention and control groups, respectively. There was no significant difference in NIHSS scores between the intervention and control groups (p = 0.682).
CONCLUSION: The effect of oral nutritional supplementation significantly reduced the NIHSS scores in acute ischemic stroke, but there was no significant difference compared to the normal hospital diet.Downloads
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Misbach J, Rasyid A, Bustamin M, Arupah U. Nutrition care process. In: Soertidewi L, Jannis J, editors. Stroke: Aspek Diagnostik, Patofisiologi, Manajemen. Jakarta: Badan Penerbit FK UI; 2011. p. 357-89.
Foley N, Teasell R, Richardson M, Wiener J, Finestone H. Nutritional intervention following stroke. In: Evidenced-Based Review of Stroke Rehabilitation; 2018. p. 1-42. Available from: https://www.ebrsr.com. [Last accesed on 2021 Mar 20].
Lieber AC, Hong E, Putrino D, Nistal DA, Pan JS, Kellner CP. Nutrition, energy expenditure, dysphagia, and self-efficacy in stroke rehabilitation: A review of the literature. Brain Sci. 2018;8(12):218. https://doi.org/10.3390/brainsci8120218 PMid:30544517 DOI: https://doi.org/10.3390/brainsci8120218
Jensen GL. Oral nutritional supplementation. Am J Manag Care. 2013;19(2):119-20. PMid:23448108
Arsava EM, Aydoğdu İ, Güngör L, Işıkay CT, Yaka E. Nutritional approach and treatment in patients with stroke, an expert opinion for Turkey. Turk Norol Derg. 2018;24(3):226-42. https://doi.org/10.4274/tnd.92603 DOI: https://doi.org/10.4274/tnd.92603
Aquilani R, Scocchi M, Iadarola P, Franciscone P, Verri M, Boschi F, et al. Protein supplementation may enhance the spontaneous recovery of neurological alterations in patients with ischaemic stroke. Clin Rehabil. 2008;22(12):1042-50. https://doi.org/10.1177/0269215508094244 PMid:19052243 DOI: https://doi.org/10.1177/0269215508094244
Hashemilar M, Khalili M, Rezaeimanesh N, AHokmabadi ES, Rasulzade S, Shamshirgaran SM, et al. Effect of whey protein supplementation on inflammatory and antioxidant markers, and clinical prognosis in acute ischemic stroke (TNS Trial): A randomized, double blind, controlled, clinical trial. Adv Pharm Bull. 2020;10(1):135-40. https://doi.org/10.15171/jcvtr.2015.24 PMid:32002373 DOI: https://doi.org/10.15171/apb.2020.018
Harrison F, May JM. Vitamin C function in the brain: Vital role of ascorbate transporter (SVCT2). Free Radic Biol Med. 2010;46(6):719-30. https://doi.org/10.1016/j.freeradbiomed.2008.12.018 PMid:19162177 DOI: https://doi.org/10.1016/j.freeradbiomed.2008.12.018
Gower-Winter SD, Levenson CW. Zinc in the central nervous system: From molecules to behavior. Biofactors. 2012;38(3):186-93. https://doi.org/10.1002/biof.1012 PMid:22473811 DOI: https://doi.org/10.1002/biof.1012
Biswas S, Giri S. Importance of choline as essential nutrient and its role in prevention of various toxicities. Prague Med Rep. 2015;116(1):5-15. https://doi.org/10.14712/23362936.2015.40 PMid:25923965 DOI: https://doi.org/10.14712/23362936.2015.40
Kennedy DO. B vitamins and the brain: Mechanisms, dose and efficacy-a review. Nutrients. 2016;8(2):68. https://doi.org/10.3390/nu8020068 PMid:26828517 DOI: https://doi.org/10.3390/nu8020068
Hunt BD, Cappuccio FP. Potassium intake and stroke risk: A review of the evidence and practical considerations for achieving a minimum target. Stroke. 2014;45(5):1519-22. https://doi.org/10.1161/STROKEAHA.113.004282 PMid:24699056 DOI: https://doi.org/10.1161/STROKEAHA.113.004282
Wang J, Shi Y, Zhang L, Zhang F, Hu X, Zhang W, et al. Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke. Neurobiol Dis. 2014;68:91-103. https://doi.org/10.1016/j.nbd.2014.04.014 PMid:24794156 DOI: https://doi.org/10.1016/j.nbd.2014.04.014
Dennis M. Routine oral nutritional supplementation for stroke patients in hospital (FOOD): A multicentre randomised controlled trial. Lancet. 2005;365(9461):755-63. https://doi.org/10.1016/ S0140-6736(05)70998-3 PMid:15733716 DOI: https://doi.org/10.1016/S0140-6736(05)17982-3
Sato Y, Yoshimura Y, Abe T. Nutrition in the first week after stroke is associated with discharge to home. Nutrients. 2021;13(3):1-9. https://doi.org/10.3390/nu13030943 PMid:33804072 DOI: https://doi.org/10.3390/nu13030943
Li M, Zhao S, Wu S, Yang X, Feng H. Effectiveness of oral nutritional supplements on older people with anorexia: A systematic review and meta-analysis of randomized controlled trials. Nutrients. 2021;13(3):1-24. https://doi.org/10.3390/nu13030835 PMid:33802580 DOI: https://doi.org/10.3390/nu13030835
Hubbard GP, Elia M, Holdoway A, Stratton RJ. A systematic review of compliance to oral nutritional supplements. Clin Nutr. 2012;31(3):293-312. https://doi.org/10.1016/j.clnu.2011.11.020 PMid:22257636 DOI: https://doi.org/10.1016/j.clnu.2011.11.020
Page F. Oral Nutritional Supplements to Tackle Malnutrition. Brussels, Belgium: Medical Nutrition International Industry; 2012. p. 82-106. Available from: https://www. medicalnutritionindustry.com
Rabadi MH, Coar PL, Lukin M, Lesser M, Blass JP. Intensive nutritional supplements can improve outcomes in stroke rehabilitation. Neurology. 2008;71(23):1856-61. https://doi.org/10.1212/01.wnl.0000327092.39422.3c DOI: https://doi.org/10.1212/01.wnl.0000327092.39422.3c
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Copyright (c) 2022 Chairil Amin Batubara, Listra Isabela Barus, Aida Fithrie (Author)
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