Squamous Cell Carcinoma with Co-infection of Microsphaeropsis arundinis and Geotrichum candidum: A Rare Case Report

Authors

  • Nurul Athirahwanti Afany Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
  • Khairuddin Djawad Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia https://orcid.org/0000-0002-4569-6385

DOI:

https://doi.org/10.3889/oamjms.2022.7994

Keywords:

Squamous cell carcinoma, Microsphaeropsis arundinis, Geotrichum candidum

Abstract

BACKGROUND: Squamous cell carcinoma (SCC) is a non-melanoma skin cancer is a malignant carcinoma with an increasing incidence. The diagnosis of SCC is mainly based on clinical features and an excisional biopsy with histologic confirmation should be performed on all clinically suspected lesions to determine the prognostic and management of SCC. The first-line treatment of SCC of the skin is complete surgical excision. Microsphaeropsis arundinis and Geotrichum candidum are types of fungi that can infect the skin.

CASE REPORT: We report a case of a 46-year-old female patient that was diagnosed with SCC based on clinical, dermoscopy, and histopathological features. In addition, M. arundinis and G. candidum were also found on culture examination, where these fungi are rarely found, especially in cases of SCC.

CONCLUSION: The patient underwent tumor excision and amputation.

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References

Mansour O, Moussa MK, Raad RD, Zreik H, Allouch AH. Squamous cell carcinoma of the heel invading the calcaneus treated by radical excision and reverse sural flap. Cureus. 2020;12(9):e10740. https://doi.org/10.7759/cureus.10740 PMid:33145143 DOI: https://doi.org/10.7759/cureus.10740

Fania L, Didona D, Di Pietro FR, Verkhovskaia S, Morese R, Paolino G, et al. Cutaneous squamous cell carcinoma: From pathophysiology to novel therapeutic approaches. Biomedicines. 2021;9(2):171. https://doi.org/10.3390/biomedicines9020171 PMid:33572373 DOI: https://doi.org/10.3390/biomedicines9020171

Neville K, Obradovic A. Verrucous carcinoma arising secondary to diabetic foot lesions: A systematic review of the literature. SKIN J Cutan Med. 2021;5(3):228-32. DOI: https://doi.org/10.25251/skin.5.3.3

Knackfuss IG, Giordano V, Godoy-Santos AL, Fernandes NC, Camargo OP. Squamous cell carcinoma in the foot: Case series and literature review. Acta Ortop Bras. 2018;26(2):108-11. https://doi.org/10.1590/1413-785220182602187183 PMid:29844733 DOI: https://doi.org/10.1590/1413-785220182602187183

Reppas G, Gottlieb T, Krockenberger M, Halliday C, Malik R. Microsphaeropsis arundinis: An emerging cause of phaeohyphomycosis in cats and people. Microbiol Aust. 2015;36:74-8. DOI: https://doi.org/10.1071/MA15025

Keene S, Sarao MS, McDonald PJ, Veltman J. Cutaneous geotrichosis due to Geotrichum candidum in a burn patient. Access Microbiol. 2019;1(1):e000001. https://doi.org/10.1099/acmi.0.000001 PMid:32974489 DOI: https://doi.org/10.1099/acmi.0.000001

Hadaschik AS, Hadaschik EN. Squamous Cell Carcinoma and Keratoacanthoma. New York: Mc Graw Hill; 2019.

Rhizlane C, Sara E, Asmae R, Soukaina C, Zakia D, Hanane B, Fatimazahra M, et al. A rare type and an unusual location of squamous cell carcinoma with bone invasion. PAMJ Clin Med. 2020;2:63. https://doi.org/10.11604/pamj-cm.2020.2.63.21376

Brothers RP, Daveluy SD. Squamous cell carcinoma mimicking fungal infection. IDCases. 2016;6:72-3. https://doi.org/10.1016/j.idcr.2016.09.016 PMid:27752471 DOI: https://doi.org/10.1016/j.idcr.2016.09.016

Azevedo CM, Marques SG, Santos DW, Silva RR, Silva NF, Santos DA, et al. Squamous cell carcinoma derived from chronic chromoblastomycosis in Brazil. Clin Infect Dis. 2015;60(10):1500-4. https://doi.org/10.1093/cid/civ104 PMid:2568137 DOI: https://doi.org/10.1093/cid/civ104

Nguyen Y, Dodds T, Lowe P. Cutaneous Microsphaeropsis arundinis infection in renal transplant recipients-a report of 2 cases and review of the literature. JAAD Case Rep. 2018;4(5):415-7. https://doi.org/10.1016/j.jdcr.2017.11.012 PMid:29984267 DOI: https://doi.org/10.1016/j.jdcr.2017.11.012

Bilman FB, Yetik M. Geotrichum candidum: A rare infection agent at urinary system and review of the literature. J Clin Exp Invest. 2017;8(4):127-9. https://doi.org/10.5799/jcei.382434 DOI: https://doi.org/10.5799/jcei.382434

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Published

2022-01-02

How to Cite

1.
Afany NA, Djawad K. Squamous Cell Carcinoma with Co-infection of Microsphaeropsis arundinis and Geotrichum candidum: A Rare Case Report. Open Access Maced J Med Sci [Internet]. 2022 Jan. 2 [cited 2024 Mar. 28];10(C):11-4. Available from: https://oamjms.eu/index.php/mjms/article/view/7994

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Case Report in Internal Medicine

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