Femtosecond Small Incision Lenticular Extraction in comparison to Femtosecond Laser In situ Keratomileusis Regarding Dry Eye Disease

Authors

  • Najah Kadhum Mohammad Department of Surgery and Ophthalmology, Baghdad College of Medicine, University of Baghdad, Baghdad, Iraq
  • Suzan Rattan Department of Surgery, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
  • Ahmed Shaker Ali Al Wassiti Department of Surgery and Ophthalmology, Baghdad College of Medicine, University of Baghdad, Baghdad, Iraq
  • Zaid Al-Attar Department of Pharmacology, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

DOI:

https://doi.org/10.3889/oamjms.2022.8040

Keywords:

Dry eye, Corneal sensitivity, Small incision lenticule extraction, Femtosecond laser-assisted laser, In situ keratomileusis, Refractive surgery

Abstract

 Abstract

Objective: Comparison of femtosecond small incision lenticule extraction (FS-SMILE) versus Femtosecond laser Insitu keratomileusis (FS-LASIK) regarding dry eye disease (DED) and corneal sensitivity (CS) after those refractive surgeries.

Methods: A comparative prospective study conducted for a period of 2 years; from March 2017 until February, 2019. Enrolled patients were diagnosed with myopia. Fifty patients (100 eyes) were scheduled for bilateral FS-SMILE and the other 50 patients (100 eyes) had been scheduled for bilateral FS-LASIK. Both groups were followed for six months after surgery. The age, gender, and preoperative refraction for both groups were matched. Complete evaluation of dry eye disease had been performed for the intervals of one week pre-operatively, one and six months postoperatively. The evaluation included history of symptoms according to scoring systems, investigations and clinical examination.

Results: One month postoperatively and in both groups, there was significant DED (P < .01), although the incidence was lower in femtosecond SMILE group, overall severity score (0-4): 0.3 ± 0.3 (FS-SMILE) vs. 1.4 ± 0.9 (LASIK). One month postoperatively, CS was lower in FS- LASIK more than FS-SMILE eyes (2.3 ± 2.2 vs 3.6 ± 1.8, respectively, P < .01) and then return to not statistically significant sensitivities at six-month duration. DED was negatively correlated with CS (P < 0.01).

Conclusions: The FS-LASIK surgery had a more pronounced effect on the CS and DED compared with FS-SMILE, with higher incidence of DED postrefractive surgery.

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References

Sekundo W, Kunert KS, Blum M. Small incision corneal refractive surgery using the small incision lenticule extraction (SMILE) procedure for the correction of myopia and myopic astigmatism: Results of a 6 month prospective study. Br J Ophthalmol. 2011;95(3):335-9. https://doi.org/10.1136/bjo.2009.174284 PMid:20601657 DOI: https://doi.org/10.1136/bjo.2009.174284

Ivarsen A, Asp S, Hjortdal J. Safety and complications of more than 1500 small-incision lenticule extraction procedures. Ophthalmology. 2014;121(4):822-8. https://doi.org/10.1016/j.ophtha.2013.11.006 PMid:24365175 DOI: https://doi.org/10.1016/j.ophtha.2013.11.006

Piñero DP, Teus MA. Clinical outcomes of small-incision lenticule extraction and femtosecond laser–assisted wavefront-guided laser in situ keratomileusis. J Cataract Refract Surg. 2016;42(7):1078-93. https://doi.org/10.1016/j.jcrs.2016.05.004 PMid:27492109 DOI: https://doi.org/10.1016/j.jcrs.2016.05.004

Chao C, Golebiowski B, Stapleton F. The role of corneal innervation in LASIK-induced neuropathic dry eye. Ocul Surf. 2014;12(1):32-45. https://doi.org/10.1016/j.jtos.2013.09.001 PMid:24439045 DOI: https://doi.org/10.1016/j.jtos.2013.09.001

Calvillo MP, McLaren JW, Hodge DO, Bourne WM. Corneal reinnervation after LASIK: Prospective 3-year longitudinal study. Invest Ophthalmol Vis Sci. 2004;45(11):3991-6. https://doi.org/10.1167/iovs.04-0561 PMid:15505047 DOI: https://doi.org/10.1167/iovs.04-0561

Feng YF, Yu JG, Wang DD, Li JH, Huang JH, Shi JL, et al. The effect of hinge location on corneal sensation and dry eye after LASIK: A systematic review and meta-analysis. Graefes Arch Clin Exp Ophthalmol. 2013;251(1):357-66. https://doi.org/10.1007/s00417-012-2078-5 PMid:22752222 DOI: https://doi.org/10.1007/s00417-012-2078-5

Behrens A, Doyle JJ, Stern L, Chuck RS, McDonnell PJ, Azar DT, et al. Dysfunctional tear syndrome: A Delphi approach to treatment recommendations. Cornea. 2006;25(8):900-7. https://doi.org/10.1097/01.ico.0000214802.40313.fa PMid:17102664 DOI: https://doi.org/10.1097/01.ico.0000214802.40313.fa

Denoyer A, Landman E, Trinh L, Faure JF, Auclin F, Baudouin C. Dry eye disease after refractive surgery: Comparative outcomes of small incision lenticule extraction versus LASIK. Ophthalmology. 2015;122(4):669-76. https://doi.org/10.1016/j.ophtha.2014.10.004 PMid:25458707 DOI: https://doi.org/10.1016/j.ophtha.2014.10.004

Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the ocular surface disease index. Arch Ophthalmol. 2000;118(5):615-21. https://doi.org/10.1001/archopht.118.5.615 PMid:10815152 DOI: https://doi.org/10.1001/archopht.118.5.615

The definition and classification of dry eye disease: Report of the definition and classification subcommittee of the international dry eye workshop (2007). Ocul Surf. 2007;5(2):75-92. https://doi.org/10.1016/s1542-0124(12)70081-2 PMid:17508116 DOI: https://doi.org/10.1016/S1542-0124(12)70081-2

Smith J, Nichols KK, Baldwin EK. Current patterns in the use of diagnostic tests in dry eye evaluation. Cornea. 2008;27(6):656-62. https://doi.org/10.1097/QAI.0b013e3181605b95 PMid:18580256 DOI: https://doi.org/10.1097/01.ico.0000611384.81547.8d

Toda I, Asano-Kato N, Komai-Hori Y, Tsubota K. Dry eye after laser in situ keratomileusis. Am J Ophthalmol. 2001;132(1):1-7. https://doi.org/10.1016/s0002-9394(01)00959-x PMid:11438046 DOI: https://doi.org/10.1016/S0002-9394(01)00959-X

Lee JB, Ryu CH, Kim J-H, Kim EK, Kim HB. Comparison of tear secretion and tear film instability after photorefractive keratectomy and laser in situ keratomileusis. J Cataract Refract Surg. 2000;26(9):1326-31. https://doi.org/10.1016/s0886-3350(00)00566-6 PMid:11020617 DOI: https://doi.org/10.1016/S0886-3350(00)00566-6

Battat L, Macri A, Dursun D, Pflugfelder SC. Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface. Ophthalmology. 2001;108(7):1230-5. https://doi.org/10.1016/s0161-6420(01)00623-6 PMid:11425680 DOI: https://doi.org/10.1016/S0161-6420(01)00623-6

Shah R, Shah S, Sengupta S. Results of small incision lenticule extraction: All-in-one femtosecond laser refractive surgery. J Cataract Refract Surg. 2011;37(1):127-37. https://doi.org/10.1016/j.jcrs.2010.07.033 PMid:21183108 DOI: https://doi.org/10.1016/j.jcrs.2010.07.033

Li M, Zhao J, Shen Y, Li T, He L, Xu H, et al. Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia. PLoS One. 2013;8(10):e77797. https://doi.org/10.1371/journal.pone.0077797 PMid:24204971 DOI: https://doi.org/10.1371/journal.pone.0077797

Linna TU, PÉRez-Santonja JJ, Tervo KM, Sakla HF, Tervo TM. Recovery of corneal nerve morphology following laser in situ keratomileusis. Exp Eye Res. 1998;66(6):755-63. https://doi.org/10.1006/exer.1998.0469 PMid:9657908 DOI: https://doi.org/10.1006/exer.1998.0469

Benitez-del-Castillo JM, del Rio T, Iradier T, Hernández JL, Castillo A, Garcia-Sanchez J. Decrease in tear secretion and corneal sensitivity after laser in situ keratomileusis. Cornea. 2001;20(1):30-2. https://doi.org/10.1097/00003226-200101000-00005 PMid:11188999 DOI: https://doi.org/10.1097/00003226-200101000-00005

Patel SV, McLaren JW, Kittleson KM, Bourne WM. Subbasal nerve density and corneal sensitivity after laser in situ keratomileusis: Femtosecond laser vs mechanical microkeratome. Arch Ophthalmol. 2010;128(11):1413-9. https://doi.org/10.1001/archophthalmol.2010.253 PMid:21060042 DOI: https://doi.org/10.1001/archophthalmol.2010.253

Petznick A, Chew A, Hall RC, Chan CM, Rosman M, Tan D, et al. Comparison of corneal sensitivity, tear function and corneal staining following laser in situ keratomileusis with two femtosecond laser platforms. Clin Ophthalmol. 2013;7:591-8. https://doi.org/10.2147/OPTH.S42266 PMid:23576858 DOI: https://doi.org/10.2147/OPTH.S42266

Kanellopoulos AJ, Pallikaris IG, Donnenfeld ED, Detorakis S, Koufala K, Perry HD. Comparison of corneal sensation following photorefractive keratectomy and laser in situ keratomileusis. J Cataract Refract Surg. 1997;23(1):34-8. https://doi.org/10.1016/s0886-3350(97)80148-4 PMid:9100105 DOI: https://doi.org/10.1016/S0886-3350(97)80148-4

Wong AH, Cheung RK, Kua WN, Shih KC, Chan TC, Wan KH. Dry eyes after SMILE. Asia Pac J Ophthalmol (Phila). 2019;8(5):397-405. https://doi.org/10.1097/01.APO.0000580136.80338.d0 PMid:31490199 DOI: https://doi.org/10.1097/01.APO.0000580136.80338.d0

Demirok A, Ozgurhan EB, Agca A, Kara N, Bozkurt E, Cankaya KI, et al. Corneal sensation after corneal refractive surgery with small incision lenticule extraction. Optom Vis Sci. 2013;90(10):1040-7. https://doi.org/10.1097/OPX.0b013e31829d9926 PMid:23939296 DOI: https://doi.org/10.1097/OPX.0b013e31829d9926

Wei S, Wang Y. Comparison of corneal sensitivity between FS-LASIK and femtosecond lenticule extraction (ReLEx flex) or small-incision lenticule extraction (ReLEx smile) for myopic eyes. Graefes Arch Clin Exp Ophthalmol. 2013;251(6):1645-54. https://doi.org/10.1007/s00417-013-2272-0 PMid:23389552 DOI: https://doi.org/10.1007/s00417-013-2272-0

Sonigo B, Iordanidou V, Chong-Sit D, Auclin F, Ancel JM, Labbe A, et al. In vivo corneal confocal microscopy comparison of intralase femtosecond laser and mechanical microkeratome for laser in situ keratomileusis. Invest Ophthalmol Vis Sci. 2006;47(7):2803-11. https://doi.org/10.1167/iovs.05-1207 PMid:16799017 DOI: https://doi.org/10.1167/iovs.05-1207

Lee BH, McLaren JW, Erie JC, Hodge DO, Bourne WM. Reinnervation in the cornea after LASIK. Invest Ophthalmol Vis Sci. 2002;43(12):3660-4. PMid:12454033

Zhang F, Deng S, Guo N, Wang M, Sun X. Confocal comparison of corneal nerve regeneration and keratocyte reaction between FS-LASIK, OUP-SBK, and conventional LASIK. Invest Ophthalmol Vis Sci. 2012;53(9):5536-44. https://doi.org/10.1167/iovs.11-8786 PMid:22786909 DOI: https://doi.org/10.1167/iovs.11-8786

Gallar J, Acosta MC, Moilanen JAO, Holopainen JM, Belmonte C, Tervo TMT. Recovery of corneal sensitivity to mechanical and chemical stimulation after laser in situ keratomileusis. Journal of Refractive Surgery. 2004;20(3):229-35. DOI: https://doi.org/10.3928/1081-597X-20040501-06

Rodriguez AE, Rodriguez-Prats JL, Hamdi IM, Galal A, Awadalla M, Alio JL. Comparison of goblet cell density after femtosecond laser and mechanical microkeratome in LASIK. Invest Ophthalmol Vis Sci. 2007;48(6):2570-5. https://doi.org/10.1167/iovs.06-1259 PMid:17525186 DOI: https://doi.org/10.1167/iovs.06-1259

Kacerovska J, Kacerovsky M, Hlavackova M, Studeny P. Change of tear osmolarity after refractive surgery. Cesk Slov Oftalmol. 201874(1):18-22. PMid:30541292 DOI: https://doi.org/10.31348/2018/1/3-1-2018

Leonardi A, Tavolato M, Curnow SJ, Fregona IA, Violato D, Alió JL. Cytokine and chemokine levels in tears and in corneal fibroblast cultures before and after excimer laser treatment. J Cataract Refract Surg. 2009;35(2):240-7. https://doi.org/10.1016/j.jcrs.2008.10.030 PMid:19185237 DOI: https://doi.org/10.1016/j.jcrs.2008.10.030

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Published

2022-02-03

How to Cite

1.
Mohammad NK, Rattan S, Al Wassiti ASA, Al-Attar Z. Femtosecond Small Incision Lenticular Extraction in comparison to Femtosecond Laser In situ Keratomileusis Regarding Dry Eye Disease. Open Access Maced J Med Sci [Internet]. 2022 Feb. 3 [cited 2024 Mar. 29];10(B):668-73. Available from: https://oamjms.eu/index.php/mjms/article/view/8040

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