Prevalence of Subclinical Keratoconus in Children with Astigmatism in Iraq
DOI:
https://doi.org/10.3889/oamjms.2022.8222Keywords:
Subclincal keratocnus, Keratoconus suspect, Diwaniya, AstigmatismAbstract
Background: Keratoconus is a progressive ectatic corneal pathology that involves both eyes, its usually asymmetrical, its early diagnosis and treatment are vital for the prevention of ocular morbidity that usually happen if it's not treated.
Aim: To detect the prevalence of subclinical keratoconus and keratoconus suspect in children with the astigmatic error of ≥2 Diopters in Diwaniya city, Iraq.
Methods: This is a cross-sectional, observational study, which investigates all the children aged six to eighteen years with an astigmatic error of ≥2 Diopters who attended the ophthalmology department for a routine eye examination during the period from January 2020 to June 2021.
All children underwent full eye examination and corneal imaging study with a modern set which is a pentagram with Scheimpflug technology.
Results: we had 488 children participated in our study, the Mean age of participants was 12.01 ± 1.24 (range 6–18) years, 255 children were males (52.2%) and 233 were female children (47.7%) and they were divided into 2 age groups: first one between 6 and 12 years 225 children ( 46.1%) the second one between 12 to 18 years include 263 children (53.8%).
We found 21 children with subclinical keratoconus ( 4.3% ) and 24 children were keratoconus suspects ( 4.9% ).
Conclusion: the prevalence of keratoconus whether subclinical or suspect among the children with astigmatism who enrolled in our study was relatively high, the use of modern imaging technique tests is vital in the diagnosis.
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Mukhtar S, Ambati BK. Pediatric keratoconus: A review of the literature. Int Ophthalmol. 2018;38(5):2257-2266. https://doi.org/10.1007/s10792-017-0699-8 PMid:28852910 DOI: https://doi.org/10.1007/s10792-017-0699-8
Mas Tur V, MacGregor C, Jayaswal R, O’Brart D, Maycock N. A review of keratoconus: Diagnosis, pathophysiology, and genetics. Surv Ophthalmol. 2017;62(6):770-783. https://doi.org/10.1016/j.survophthal.2017.06.009 PMid:28688894 DOI: https://doi.org/10.1016/j.survophthal.2017.06.009
Torres Netto EA, Al-Otaibi WM, Hafezi NL, Kling S, Al-Farhan HM, Randleman JB, et al. Prevalence of keratoconus in paediatric patients in Riyadh, Saudi Arabia. Br J Ophthalmol. 2018;102(10):1436-41. https://doi.org/10.1136/bjophthalmol-2017-311391 PMid:29298777 DOI: https://doi.org/10.1136/bjophthalmol-2017-311391
El-Khoury S, Abdelmassih Y, Hamade A, Slim E, Cherfan CG, Chelala E, et al. Pediatric keratoconus in a tertiary referral center: Incidence, presentation, risk factors, and treatment. J Refract Surg. 2016;32(8):534-541. https://doi.org/10.3928/1081597X-20160513-01 PMid:27505314 DOI: https://doi.org/10.3928/1081597X-20160513-01
Balasubramanian SA, Pye DC, Willcox MD. Effects of eye rubbing on the levels of protease, protease activity and cytokines in tears: Relevance in keratoconus. Clin Exp Optom. 2013;96(2):214-8. https://doi.org/10.1111/cxo.12038 PMid:23496656 DOI: https://doi.org/10.1111/cxo.12038
de Sanctis U, Loiacono C, Richiardi L, Turco D, Mutani B, Grignolo FM. Sensitivity and specificity of posterior corneal elevation measured by Pentacam in discriminating keratoconus/ subclinical keratoconus. Ophthalmology. 2008;115(9):1534-9. https://doi.org/10.1016/j.ophtha.2008.02.020 PMid:18405974 DOI: https://doi.org/10.1016/j.ophtha.2008.02.020
de Sanctis U, Missolungi A, Mutani B, Richiardi L, Grignolo FM. Reproducibility and repeatability of central corneal thickness measurement in keratoconus using the rotating Scheimpflug camera and ultrasound pachymetry. Am J Ophthalmol. 2007;144(5):712-8. https://doi.org/10.1016/j.ajo.2007.07.021 PMid:17869208 DOI: https://doi.org/10.1016/j.ajo.2007.07.021
Waked N, Fayad AM, Fadlallah A, El Rami H. Dépistage du kératocône dans une population universitaire au Liban [Keratoconus screening in a Lebanese students’ population]. J Fr Ophthalmol. 2012;35(1):23-29. https://doi.org/10.1016/j.jfo.2011.03.016 PMid:21715046
Millodot M, Shneor E, Albou S, Atlani E, Gordon-Shaag A. Prevalence and associated factors of keratoconus in Jerusalem: A cross-sectional study. Ophthalmic Epidemiol. 2011;18(2):91-7. https://doi.org/10.3109/09286586.2011.560747 PMid:21401417 DOI: https://doi.org/10.3109/09286586.2011.560747
Waked N, Fayad AM, Fadlallah A, El Rami H. Keratoconus screening in a Lebanesestudents’ population. J Fr Ophtalmol 2012;35(1):23-9. https://doi.org/10.1016/j.jfo.2011.03.016 PMid:21715046 DOI: https://doi.org/10.1016/j.jfo.2011.03.016
Hashemi H, Beiranvand A, Khabazkhoob M, Asgari S, Emamian MH, Shariati M, et al. Prevalence of keratoconus in a population-based study in Shahroud. Cornea. 2013;32(11):1441-5. https://doi.org/10.1097/ICO.0b013e3182a0d014 PMid:24042484 DOI: https://doi.org/10.1097/ICO.0b013e3182a0d014
Hashemi H, Khabazkhoob M, Yazdani N, Ostadimoghaddam H, Norouzirad R, Amanzadeh K, et al. The prevalence of keratoconus in a young population in Mashhad, Iran. Ophthalmic Physiol Opt. 2014;34(5):519-27. https://doi.org/10.1111/opo.12147 PMid:25131846 DOI: https://doi.org/10.1111/opo.12147
Shneor E, Millodot M, Gordon-Shaag A, Essa M, Anton M, Barbara R, et al. Prevalence of keratoconus among Young Arab students in Israel. Int J Keratoconus Ectatic Corneal Dis 2014;3:9-14. DOI: https://doi.org/10.5005/jp-journals-10025-1070
Shehadeh MM, Diakonis VF, Jalil SA, Younis R, Qadoumi J, Al-Labadi L. Prevalence of keratoconus among a palestinian tertiary student population. Open Ophthalmol J. 2015;9:172-6. https://doi.org/10.2174/1874364101509010172 PMid:26962381 DOI: https://doi.org/10.2174/1874364101509010172
Pearson AR, Soneji B, Sarvananthan N, Sandford-Smith JH. Does ethnic origin influence the incidence or severity of keratoconus? Eye. 2000;14(Pt 4):625-8. https://doi.org/10.1038/eye.2000.154 PMid:11040911 DOI: https://doi.org/10.1038/eye.2000.154
Jonas JB, Nangia V, Matin A, Kulkarni M, Bhojwani K. Prevalence and associations of keratoconus in rural maharashtra in central India: The central India eye and medical study. Am JOphthalmol. 2009;148(5):760-5. https://doi.org/10.1016/j.ajo.2009.06.024 PMid:19674732 DOI: https://doi.org/10.1016/j.ajo.2009.06.024
Xu L, Wang YX, Guo Y, You QS, Jonas JB, Beijing Eye Study Group. Prevalence and associations of steep cornea/ keratoconus in Greater Beijing. The Beijing Eye Study. PLoS One. 2012;7(7):e39313. https://doi.org/10.1371/journal.pone.0039313 PMid:22792169 DOI: https://doi.org/10.1371/journal.pone.0039313
Godefrooij DA, de Wit GA, Uiterwaal CS, Imhof SM, Wisse RP. Age-specific incidence and prevalence of keratoconus: A nationwide registration study. Am J Ophthalmol 2017;175:169-72. DOI: https://doi.org/10.1016/j.ajo.2016.12.015
Hashemi H, Khabazkhoob M, Fotouhi A. Topographic keratoconus is not rare in an iranian population: The Tehran eye study. Ophthalmic Epidemiol. 2013;20(6):385-91. https://doi.org/10.3109/09286586.2013.848458 PMid:24168025 DOI: https://doi.org/10.3109/09286586.2013.848458
Elbedewy HA, Wasfy TE, Soliman SS, Sabry MM, Awara A, El Emam SY, et al. Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta. Int Ophthalmol. 2019;39(7):1459-65. https://doi.org/10.1007/s10792-018-0965-4 PMid:29938312 DOI: https://doi.org/10.1007/s10792-018-0965-4
Krachmer JH, Feder RS, Belin MW. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol. 1984;28:293-322. https://doi.org/10.1016/0039-6257(84)90094-8 PMid:6230745 DOI: https://doi.org/10.1016/0039-6257(84)90094-8
Gokhale NS. Epidemiology of keratoconus. Indian J Ophthalmol. 2013;61:382-3. https://doi.org/10.4103/0301-4738.116054 PMid:23925318 DOI: https://doi.org/10.4103/0301-4738.116054
Awwad ST, Yehia M, Mehanna CJ, Abdul Fattah M, Saad A, Hatoum A, et al. Tomographic and refractive characteristics of pediatric first-degree relatives of keratoconuspatients. Am J Ophthalmol. 2019;207:71-6. https://doi.org/10.1016/j.ajo.2019.05.032 PMid:31194951 DOI: https://doi.org/10.1016/j.ajo.2019.05.032
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Copyright (c) 2022 Haider Layikh, Farooq M. Abbas, Hasanain H. Attar, Alyaa A. Kadhum (Author)
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