Pregnant Women Infected with Coronavirus Disease 2019 Pneumonia: A Case Series in Medan, Indonesia

Authors

  • Bintang Yinke Magdalena Sinaga Department of Pulmonology and Respiratory Medicine, Division of Infection, Universitas Sumatera Utara, Medan, Indonesia https://orcid.org/0000-0003-1447-3266
  • Fannie Rizki Ananda Department of Pulmonology and Respiratory Medicine, Universitas Sumatera Utara, Medan, Indonesia https://orcid.org/0000-0002-5982-2194

DOI:

https://doi.org/10.3889/oamjms.2022.8272

Keywords:

COVID-19, Fetal outcome, High-risk thrombosis, Maternal outcome, Pregnant women

Abstract

BACKGROUND: Pregnancy state affects the immune regulation including physical barrier, innate, and adaptive immunity-related to susceptibility of infections and increasing risk for severe to critical case of COVID-19. Further, high risk of thrombosis becomes a challenge in the management of COVID19 in pregnancy due to the strong association with worse outcome.

CASE REPORT: Here, we present three cases of pregnant women infected with COVID-19 pneumonia with different outcomes in maternal and fetal condition related to high-risk thrombosis. Serial inflammatory markers were needed to the early detect the disease progressivity in pregnant women with COVID-19. Further, complete assessment of fetus including reverse transcriptase-polymerase chain reaction and chest X-ray must be performed to the early diagnosis of COVID-19 in neonatal whose mother was infected by SARS-CoV-2.

CONCLUSION: Pregnancy state affects the immune regulation including physical barrier, innate, and adaptive immunity-related to susceptibility of infections and increasing risk for severe to critical case of COVID-19. Further, high risk of thrombosis becomes a challenge in the management of COVID19 in pregnancy due to the strong association with worse outcome. Although fetal transmission of COVID-19 to fetus remains unclear, complete assessment of fetus including RT-PCR, and chest X-ray must be performed to the early diagnosis of COVID-19 in neonatal whose mother was infected by SARS-CoV-2.

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Published

2022-02-07

How to Cite

1.
Sinaga BYM, Ananda FR. Pregnant Women Infected with Coronavirus Disease 2019 Pneumonia: A Case Series in Medan, Indonesia. Open Access Maced J Med Sci [Internet]. 2022 Feb. 7 [cited 2024 May 26];10(C):246-51. Available from: https://oamjms.eu/index.php/mjms/article/view/8272

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Case Report in Internal Medicine

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