Risk Factors for Post-operative Ileus: A Retrospective Study in Tertiary Referral Hospital in Indonesia

Authors

  • Made Agus Dwianthara Sueta Department of Surgery, Division of Digestive Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia
  • Nyoman Golden Department of Neurosurgery, Faculty of Medicine, Universitas Udayana, Sanglah Hospital, Bali, Indonesia
  • Mira Dewi Prawira Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.8286

Keywords:

Post-operative ileus, Risk factor, Laparotomic, Resection, Anastomosis

Abstract

Background: Postoperative ileus is a complication that may result in the longer duration of stay and decreases the quality of life of patients. Previous studies have found some factors related to postoperative ileus. This study aimed to determine the risk factor of postoperative ileus in laparotomic resection and anastomosis surgery.

Methods: Patients who underwent laparotomic resection and anastomosis surgery during January 2019 – July 2020 were included. Postoperative ileus was diagnosed in fourth day after surgery. The variables included in this study are age, gender, BMI, pathology site, duration of surgery, type of anastomosis, length of resection.

Result: Fifty laparotomic resection and anastomosis surgery patients were included in this study, 50% of subjects is patients with postoperative ileus. Patient aged 65 years old or older had a higher incidence postoperative ileus (68% vs 28%; RR 2.3 95% CI: 1.23-4.33; p value: 0.010). Study also found duration of surgery 180 minutes or longer also had higher incidence postoperative ileus (79% vs 36%; RR: 2.49 95% CI: 1.20-5.15; p value: 0.010).

Conclusion: This study concludes that age 65 years old or older and duration of surgery 180 minutes or longer are significant risk factor to postoperative ileus in laparotomic resection and anastomosis surgery patients.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Reference Vather R, Trivedi S, Bissett I. Defining postoperative ileus: Results of a systematic review and global survey. J Gastrointest Surg. 2013;17:962-72. https://doi.org/10.1007/s11605-013-2148-y PMid:23377782 DOI: https://doi.org/10.1007/s11605-013-2148-y

Venara A, Neunlist M, Slim K, Barbieux J, Colas PA, Hamy A, et al. Postoperative ileus: Pathophysiology, incidence, and prevention. J Visc Surg. 2016;153(6):439-46. https://doi.org/10.1016/j.jviscsurg.2016.08.010 PMid:27666979 DOI: https://doi.org/10.1016/j.jviscsurg.2016.08.010

Delaney CP. Clinical perspective on postoperative ileus and the effect of opiates. Neurogastroenterol Motil. 2004;16(2):61-6. https://doi.org/10.1111/j.1743-3150.2004.00559.x PMid:15357853 DOI: https://doi.org/10.1111/j.1743-3150.2004.00559.x

Wolthuis AM, Bislenghi G, Fieuws S, de Buck van Overstraeten A, Boeckxstaens G, D’Hoore A, et al. Incidence of prolonged postoperative ileus after colorectal surgery: A systematic review and meta-analysis. Color Dis. 2016;18(1):1-9. https://doi.org/10.1111/codi.13210 PMid:26558477 DOI: https://doi.org/10.1111/codi.13210

Asgeirsson T, El-Badawi KI, Mahmood A, Barletta J, Luchtefeld M, Senagore AJ, et al. Postoperative ileus: It costs more than you expect. J Am Coll Surg. 2010;210(2):228-31. https://doi.org/10.1016/j.jamcollsurg.2009.09.028 PMid:20113944 DOI: https://doi.org/10.1016/j.jamcollsurg.2009.09.028

Courtot L, Le Roy B, Memeo R, Voron T, de Angelis N, Tabchouri N, et al. Risk factors for postoperative ileus following elective laparoscopic right colectomy: A retrospective multicentric study. Int J Color Dis. 2018;33(10):1373-82. https://doi.org/10.1007/s00384-018-3070-2 PMid:29732465 DOI: https://doi.org/10.1007/s00384-018-3070-2

Hiranyakas A, Bashankaev B, Seo CJ, Khaikin M, Wexner SD. Epidemiology, pathophysiology and medical management of postoperative ileus in the elderly. Drugs Aging. 2011;28(2):107-18. https://doi.org/10.2165/11586170-000000000-00000 PMid:21275436 DOI: https://doi.org/10.2165/11586170-000000000-00000

Ay AA, Kutun S, Ulucanlar H, Tarcan O, Demir A, Cetin A. Risk factors for postoperative ileus. J Korean Surg Soc. 2011;81(4):242-9. https://doi.org/10.4174/jkss.2011.81.4.242 PMid:22111079 DOI: https://doi.org/10.4174/jkss.2011.81.4.242

Morimoto Y, Takahashi H, Fujii M, Miyoshi N, Uemura M, Matsuda C, et al. Visceral obesity is a preoperative risk factor for postoperative ileus after surgery for colorectal cancer: Single-institution retrospective analysis. Ann Gastroenterol Surg. 2019;3(6):657-66. https://doi.org/10.1002/ags3.12291 PMid:31788654 DOI: https://doi.org/10.1002/ags3.12291

Svatek RS, Fisher MB, Williams MB, Matin SF, Kamat AM, Grossman HB, et al. Are independent risk factors paralytic ileus after radical cystectomy. Urology. 2010;76(6):1419-24. https://doi.org/10.1016/j.urology.2010.02.053 PMid:20472264 DOI: https://doi.org/10.1016/j.urology.2010.02.053

Moghadamyeghaneh Z, Hwang GS, Hanna MH, Phelan M, Carmichael JC, Mills S, et al. Risk factors for prolonged ileus following colon surgery. Surg Endosc. 2016;30(2):603-9. https://doi.org/10.1007/s00464-015-4247-1 PMid:26017914 DOI: https://doi.org/10.1007/s00464-015-4247-1

Vather R, Josephson R, Jaung R. Development of a risk stratification system for the occurrence of prolonged postoperative ileus after colorectal surgery : A prospective risk factor analysis. Surgery. 2014;157(4):764-73. https://doi.org/10.1016/j.surg.2014.12.005 PMid:25724094 DOI: https://doi.org/10.1016/j.surg.2014.12.005

Behm B, Stollman N. Postoperative ileus : Etiologies and interventions. Clin Gastroenterol Hepatol. 2003;1(2):71-80. https://doi.org/10.1053/cgh.2003.50012 PMid:15017498 DOI: https://doi.org/10.1053/cgh.2003.50012

Artinyan A, Nunoo-Mensah JW, Balasubramaniam S, Gauderman J, Essani R, Gonzalez-Ruiz C, et al. Prolonged postoperative ileus-definition, risk factors, and predictors after surgery. World J Surg. 2008;32(7):1495-500. https://doi.org/10.1007/s00268-008-9491-2 PMid:18305994 DOI: https://doi.org/10.1007/s00268-008-9491-2

Grass F, Slieker J, Jurt J, Kummer A, Solà J, Hahnloser D, et al. Postoperative ileus in an enhanced recovery pathway-a retrospective cohort study. Int J Colorectal Dis. 2017;32(5):675-81. https://doi.org/10.1007/s00384-017-2789-5 PMid:28285365 DOI: https://doi.org/10.1007/s00384-017-2789-5

Luckey A, Livingston E, Taché Y. Mechanisms and treatment of postoperative ileus. Arch Surg. 2003;138(2):206-14. https://doi.org/10.1001/archsurg.138.2.206 PMid:12578422 DOI: https://doi.org/10.1001/archsurg.138.2.206

Jørgensen H, Wetterslev J, Møiniche S, Dahl JB. Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. Cochrane Database Syst Rev. 2000;4:CD001893. DOI: https://doi.org/10.1002/14651858.CD001893

Downloads

Published

2022-02-15

How to Cite

1.
Sueta MAD, Golden N, Prawira MD. Risk Factors for Post-operative Ileus: A Retrospective Study in Tertiary Referral Hospital in Indonesia. Open Access Maced J Med Sci [Internet]. 2022 Feb. 15 [cited 2024 Mar. 28];10(B):1148-52. Available from: https://oamjms.eu/index.php/mjms/article/view/8286

Most read articles by the same author(s)