Application of Chitosan and Hydroxyapatite in Periodontal Tissue Regeneration: A Review

Asdar Gani; Risfah Yulianti; Supiaty Supiaty; Machirah Rusdy

doi:10.3889/oamjms.2022.8423

Authors

Asdar Gani Department of Periodontology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia https://orcid.org/0000-0002-8393-8082
Risfah Yulianti Department of Pharmaceutical Science and Technology, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia
Supiaty Supiaty Periodontal Specialist Dental Education Program, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Machirah Rusdy Periodontal Specialist Dental Education Program, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia https://orcid.org/0000-0002-1412-0412

DOI:

https://doi.org/10.3889/oamjms.2022.8423

Keywords:

Chitosan, Hydroxyapatite, Periodontal regeneration, Graft

Abstract

Chronic periodontitis is an infection caused by bacteria in the gum tissue that supports the teeth. The current periodontal therapy manages or removes periodontal infections and repairs the periodontium destroyed due to periodontal disease. Due to its biodegradability and biocompatibility, chitosan (CH) and hydroxyapatite (HAP) are employed for bone tissue healing. The purpose of this study was to compare the utilization of CH and HAP in the regeneration of periodontal tissue. The presented study is a systematic review prepared from a collection of recent relevant published articles. This research was conducted by reviewing articles from 2016 to August 2021. The analysis found that CH/HAP is a therapeutic strategy for chronic periodontitis patients that allow low-cost bone regeneration, mHA/CH scaffolds may inhibit the growth of periodontal pathogens, and CH or HAP has the potential to be developed bone tissue engineering.

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