Pinctada Maxima Pearl Shells as a Promising Bone Graft Material in the World of Dentistry

Authors

  • M. Hendra Chandha Department of Maxillofacial Surgery, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Surijana Mappangara Department of Periodontology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Harun Achmad Department of Pediatric Dentistry, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia https://orcid.org/0000-0003-3124-2064
  • Sri Oktawati Department of Periodontology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Sitti Raoda Juanita Ramadhan Periodontology Specialist Educational Program, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Muhammad Yudin Periodontology Specialist Educational Program, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia https://orcid.org/0000-0002-1461-624X
  • Gustivanny Dwipa Asri Periodontology Specialist Educational Program, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia https://orcid.org/0000-0002-4261-6925

DOI:

https://doi.org/10.3889/oamjms.2022.8529

Keywords:

Bone graft, Bone morphogenetic protein, Bone remodeling, Hydroxyapatite, Osteoprotegerin

Abstract

BACKGROUND: Pinctada maxima pearl shell contains inorganic and organic materials that have a bone-like basic structure that facilitates bone remodeling.

AIM: This study aimed to describe the effectiveness of Pinctada maxima pearl shells as bone graft material in the world of dentistry using an animal model.

METHODS: Research uses Pinctada maxima pearl shell that was processed into hydroxyapatite Pinctada maxima (HPM) powder. Chemical and surface characteristics of HPM were performed with X-ray fluorescence (XRF), Fourier transform infra-red (FTIR), and X-ray diffraction (XRD), respectively. Thirty male guinea pigs were randomly assigned into three groups: Negative control (NC), positive control, and HPM. After 14–21 days of observation, guinea pigs were sacrificed. Bone formation was seen through immunohistochemical examination of osteoprotegerin (OPG) and bone morphogenetic protein (BMP2) expression. Data were analyzed through Shapiro wills and analysis of variance with a significance level of 5%.

RESULTS: There was a high expression of OPG and BMP2 on days 14–21 in the HPM group when compared to the NC group with a significance level of 5%.

CONCLUSION: HPM powder can be used as a promising bone graft material in the world of dentistry.

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Published

2022-02-16

How to Cite

1.
Chandha MH, Mappangara S, Achmad H, Oktawati S, Ramadhan SRJ, Yudin M, Asri GD. Pinctada Maxima Pearl Shells as a Promising Bone Graft Material in the World of Dentistry. Open Access Maced J Med Sci [Internet]. 2022 Feb. 16 [cited 2024 Mar. 28];10(D):109-15. Available from: https://oamjms.eu/index.php/mjms/article/view/8529

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Periodontology and Oral Medicine

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