The Efficacy of Topical Photodynamic Therapy in Precancerous Lesions of the Skin: A Literature Review


  • Imam Budi Putra Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia
  • Nelva Karmila Jusuf Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia
  • Calvina Theresia Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia



topical photodynamic therapy, precancerous skin lesions, actinic keratosis, Bowen’s disease


Precancerous skin lesions are associated with high probability of malignant transformation to squamous cell carcinoma. Early detection and management are necessary to improve prognosis and outcomes. Literatures showed that topical photodynamic therapy (PDT) is a promising treatment method which can be successfully applied in several conditions in dermatology. This study aims to review the efficacy of topical PDT for various precancerous lesions in dermatology, such as actinic keratosis, Bowen disease, and Bowenoid papulosis.


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How to Cite

Putra IB, Jusuf NK, Theresia C. The Efficacy of Topical Photodynamic Therapy in Precancerous Lesions of the Skin: A Literature Review. Open Access Maced J Med Sci [Internet]. 2022 Feb. 15 [cited 2024 Feb. 26];10(F):86-9. Available from:



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