The Efficacy of Topical Photodynamic Therapy in Precancerous Lesions of the Skin: A Literature Review

Imam Budi Putra; Nelva Karmila Jusuf; Calvina Theresia

doi:10.3889/oamjms.2022.8543

Authors

Imam Budi Putra Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia https://orcid.org/0000-0003-2678-3747
Nelva Karmila Jusuf Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia
Calvina Theresia Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Universitas Sumatera Utara Hospital, Medan, Indonesia https://orcid.org/0000-0003-2678-3747

DOI:

https://doi.org/10.3889/oamjms.2022.8543

Keywords:

topical photodynamic therapy, precancerous skin lesions, actinic keratosis, Bowen’s disease

Abstract

Precancerous skin lesions are associated with high probability of malignant transformation to squamous cell carcinoma. Early detection and management are necessary to improve prognosis and outcomes. Literatures showed that topical photodynamic therapy (PDT) is a promising treatment method which can be successfully applied in several conditions in dermatology. This study aims to review the efficacy of topical PDT for various precancerous lesions in dermatology, such as actinic keratosis, Bowen disease, and Bowenoid papulosis.

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