Eumycetoma Pedis Due to Madurella mycetomatis in Indonesian Farmer: A Case Report

Authors

  • Emma Novauli Hutabarat Department of Dermatology and Venerology, Faculty of Medicine, University of Hasanuddin, Wahidin Sudirohusodo Hospital, Makassar, South Sulawesi, Indonesia
  • Faridha Ilyas Department of Dermatology and Venerology, Faculty of Medicine, University of Hasanuddin, Wahidin Sudirohusodo Hospital, Makassar, South Sulawesi, Indonesia
  • Safruddin Amin Department of Dermatology and Venerology, Faculty of Medicine, University of Hasanuddin, Wahidin Sudirohusodo Hospital, Makassar, South Sulawesi, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.8630

Keywords:

Mycetoma, Pedis, Itraconazole, Endemic

Abstract

BACKGROUND: Mycetoma is a chronic, localized cutaneous inflammatory disease originating from fungi (eumycetoma) or bacteria (actinomycetoma) infection. The most common cause of eumycetoma is a black grain producing fungus, Madurella mycetoma.

CASE PRESENTATION: We present a case of eumycetoma pedis in a middle-aged woman with a successful resolution after receiving the combination of surgical debridement, systemic itraconazole, and topical antifungals therapy.

CONCLUSION: This case report highlights the importance of a prompt diagnostic procedure to identify the causative agent in mycetoma at an early stage of the disease followed by integrated management care that combines systemic therapy and surgical intervention.

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References

Welsh O, Al-Abdely HM, Salinas-Carmona MC, Fahal AH. Mycetoma medical therapy. PLoS Negl Trop Dis. 2014;8(10):e3218. https://doi.org/10.1371/journal.pntd.0003218 PMid:25330342 DOI: https://doi.org/10.1371/journal.pntd.0003218

Venkatswami S, Sankarasubramanian A, Subramanyam S. The madura foot: Looking deep. Int J Low Extrem Wounds. 2012;11:31-42. https://doi.org/10.1177/1534734612438549 PMid:22334597 DOI: https://doi.org/10.1177/1534734612438549

Elkheir LYM, Haroun R, Mohamed MA, Fahal AH. Madurella mycetomatis causing eumycetoma medical treatment: The challenges and prospects. PLoS Negl Trop Dis. 2020;14(8):e0008307. https://doi.org/10.1371/journal.pntd.0008307 PMid:32853199 DOI: https://doi.org/10.1371/journal.pntd.0008307

Fahal A, El Mahgoub S, El Hassan AM, Abdel-Rahman ME, Alshambaty Y, Hashim A, et al. A new model for management of mycetoma in the Sudan. PLoS Negl Trop Dis. 2014;8(10):e3271. https://doi.org/10.1371/journal.pntd.0003271 PMid:25356640 DOI: https://doi.org/10.1371/journal.pntd.0003271

Emmanuel P, Dumre SP, John S, Karbwang J, Hirayama K. Mycetoma: A clinical dilemma in resource limited settings. Ann Clin Microbiol Antimicrob. 2018;17(1):35. https://doi.org/10.1186/s12941-018-0287-4 PMid:30097030 DOI: https://doi.org/10.1186/s12941-018-0287-4

Sigera LS, Narangoda KU, Dahanayake MY, Shabri UL, Malkanthi MA, Somarathne V, et al. Mycetoma due to Madurella mycetomatis. IDCases. 2020 May 30;21:e00857. https://doi.org/10.1016/j.idcr.2020.e00857 PMid:32528849 DOI: https://doi.org/10.1016/j.idcr.2020.e00857

Relhan V, Mahajan K, Agarwal P, Garg VK. Mycetoma: An update. Indian J Dermatol. 2017;62(4):332-40. https://doi.org/10.4103/ijd.IJD_476_16 PMid:28794542 DOI: https://doi.org/10.4103/ijd.IJD_476_16

Sen A, Pillay RS. Case report: Dot-in-circle sign-an MRI and USG sign for “Madura foot”. Indian J Radiol Imaging. 2011;21(4):264-6. https://doi.org/10.4103/0971-3026.90684 PMid:22223936 DOI: https://doi.org/10.4103/0971-3026.90684

Laohawiriyakamol T, Tanutit P, Kanjanapradit K, Hongsakul K, Ehara S. The “dot-in-circle” sign in musculoskeletal mycetoma on magnetic resonance imaging and ultrasonography. Springerplus. 2014;3:671. https://doi.org/10.1186/2193-1801-3-671 PMid:25485205 DOI: https://doi.org/10.1186/2193-1801-3-671

Siddig ED, Fahal AH. Histopathological approach in diagnosis of mycetoma causative agents: A mini review. J Cytol Histol. 2017;8(3):1-3.

Zijlstra EE, van de Sande WW, Fahal AH. Mycetoma: A long journey from neglect. PLoS Negl Trop Dis. 2016;10(1):e0004244. https://doi.org/10.1371/journal.pntd.0004244 PMid:26797103 DOI: https://doi.org/10.1371/journal.pntd.0004244

Alam K, Maheshwari V, Bhargava S, Jain A, Fatima U, Haq EU. Histological diagnosis of Madura foot (mycetoma): A must for definitive treatment. J Glob Infect Dis. 2009;1:64-7. https://doi.org/10.4103/0974-777X.52985 PMid:20300390 DOI: https://doi.org/10.4103/0974-777X.52985

Estrada R, Lopez GC, Chavez GE, Martinez RL, Welsh O. Eumycetoma. Clin Dermatol. 2012;30(4):389-96. https://doi.org/10.1016/j.clindermatol.2011.09.009 PMid:22682186 DOI: https://doi.org/10.1016/j.clindermatol.2011.09.009

Schibli A, Goldenberger D, Krieg A, Hirschmann A, Bruder E, Osthoff M. Painless swelling of the forefoot and recurrent subcutaneous abscesses of the lower leg-Two distinct presentations illustrating the spectrum of eumycetoma in a nonendemic country. PLoS Negl Trop Dis. 2017;11(4):e0005360. https://doi.org/10.1371/journal.pntd.0005360 PMid:28406907 DOI: https://doi.org/10.1371/journal.pntd.0005360

Fahal AH, Rahman IA, El-Hassan AM, Rahman ME, Zijlstra EE. The safety and efficacy of itraconazole for the treatment of patients with eumycetoma due to Madurella mycetomatis. Trans R Soc Trop Med Hyg. 2011;105:127-32. https://doi.org/10.1016/j.trstmh.2010.11.008 PMid:21247608 DOI: https://doi.org/10.1016/j.trstmh.2010.11.008

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Published

2022-02-23

How to Cite

1.
Hutabarat EN, Ilyas F, Amin S. Eumycetoma Pedis Due to Madurella mycetomatis in Indonesian Farmer: A Case Report. Open Access Maced J Med Sci [Internet]. 2022 Feb. 23 [cited 2024 Nov. 23];10(C):80-4. Available from: https://oamjms.eu/index.php/mjms/article/view/8630

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Case Report in Internal Medicine

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