Time Trends of Epidemiology of Hemorrhagic Stroke among Urban Population in Kazakhstan


  • Yevgeniy Zhukov Kazakhstan School of Public Health, Kazakhstan Medical University, Almaty, Republic of Kazakhstan; Department of Medicine, City Clinical Hospital No7, Almaty, Republic of Kazakhstan
  • Yermek Kavtaevich Kavtaevich Dyussembekov Department of Medicine, City Clinical Hospital No7, Almaty, Republic of Kazakhstan
  • Аltyn Aringazina Kazakhstan School of Public Health, Kazakhstan Medical University, Almaty, Republic of Kazakhstan
  • Rauan Kastey Department of Medicine, City Clinical Hospital No7, Almaty, Republic of Kazakhstan
  • Kuanysh Nikatov Department of Medicine, City Clinical Hospital No7, Almaty, Republic of Kazakhstan
  • Arimantas Tamasauskas Department of Medicine, Neuroscience Institute, Lithuanian University of Health Sciences, Kaunas, Lithuania
  • Ruslan Kulmanbetov Department of Medicine, S.D. Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan
  • Anar Tursynbekova Department of Medicine, Research Institute of Cardiology and Internal Diseases, Almaty, Republic of Kazakhstan
  • Ydyrys Almabayev Department of Medicine https://orcid.org/0000-0002-5268-1675




Hemorrhagic stroke, Subarachnoid hemorrhage, Cardiovascular disease, Kazakhstan


AIM: Central Asia has been known among the highest hemorrhagic stroke (HS) and subarachnoid hemorrhage (SAH) burden regions globally. Despite the decline in cardiovascular disease mortality (CVD), HS and SAH have been remaining a public health concern in Kazakhstan. This study aimed to evaluate the trends of HS and SAH among the urban population in Kazakhstan.

METHODS: We studied HS and SAH cases aged 18 years and older between 2013 and 2017 hospitalized to stroke centers in Almaty (Kazakhstan). HS and SAH were confirmed by neuroimaging. We calculated age-standardized event, mortality and in-hospital case-fatality rates (per 100,000 populations) with 95% CIs for each individual year and over the five years using SAS University Edition and Joinpoint Regression Program.

RESULTS: Out of 2759 HS and 413 SAH cases admitted into the stroke centers of Almaty (Kazakhstan), 27.4% cases died in a hospital. The age-standardized HS event rates decreased in both sexes over the five years while age-standardized SAH event rates increased for the same period of time. The age-standardized mortality and case-fatality rates decreased in women among HS and SAH cases and men with HS. However, the age-standardized mortality and case-fatality SAH rates increased in men over same period.

CONCLUSIONS: Despite the overall decline in HS and slight increase in SAH over the 5 years, the burden remains high. We need to further monitor HS and SAH trends to develop targeted interventions and ensure that the preventive strategies are reducing the burden.



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How to Cite

Zhukov Y, Dyussembekov YKK, Aringazina А, Kastey R, Nikatov K, Tamasauskas A, Kulmanbetov R, Tursynbekova A, Almabayev Y. Time Trends of Epidemiology of Hemorrhagic Stroke among Urban Population in Kazakhstan. Open Access Maced J Med Sci [Internet]. 2022 Feb. 5 [cited 2024 Feb. 23];10(A):402-8. Available from: https://oamjms.eu/index.php/mjms/article/view/8688

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