Poor Glycaemic Control and its Associated Factors among Type 2 Diabetes Mellitus Patients in Southern Part of Peninsular Malaysia: A Registry-based Study

Authors

  • Norizzati Amsah Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia https://orcid.org/0000-0003-2531-5159
  • Zaleha Md Isa Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia
  • Zaid Kassim Segamat District Health Office, Jalan Gudang Ubat, Segamat, Johor, Malaysia

DOI:

https://doi.org/10.3889/oamjms.2022.8696

Keywords:

Risk factors, Determinants, Type 2 diabetes mellitus, Hyperglycemia, Glycemic control

Abstract

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a growing global health concern that is likely to reach a pandemic level by 2030 and is one of the leading causes of death globally. Recently, T2DM has been causing an increase in premature mortality including in developing countries.

AIM: This study aimed to determine the prevalence and the factors associated with poor glycaemic control among Type 2 diabetes mellitus (T2DM) patients in Segamat, Malaysia. 

METHOD: The study population was selected from the National Diabetic Registry (NDR) database between June 2019 and September 2020 which included a total of 3,100 patients. General and clinical information were retrieved from the registry. Glycaemic control was categorised as good (HbA1c ≤6.5 %) or poor (HbA1c >6.5%). Univariable and multivariable logistic regression were performed to assess the factors of poor glycaemic control

RESULTS: More than half (59.2%) of the patients had poor glycaemic control. As high as 55.1% of older patients (≥60 years old) had poorer glycaemic control. Most patients with poor glycaemic control (62.0%) were obese. Multiple logistic regression analysis revealed that age (≥60 years old), ethnicity (Malay and Indian), more than 10 years of diabetes, obesity, early diabetes onset before 40 years, and dyslipidaemia were associated with poor glycaemic control.

CONCLUSION: These findings can provide the necessary guidance for the stakeholders in identifying T2DM patients at risk of poor glycaemic control so that early preventive measures and organised care can be provided for the patients.

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References

International Diabetes Federation. Type 2 Diabetes. Brussels, Belgium: International Diabetes Federation; 2020. Available from: https://www.idf.org/aboutdiabetes/type-2-diabetes.html# [Last accessed on 2021 May 25].

Papatheodorou K, Banach M, Edmonds M, Papanas N, Papazoglou D. Complications of Diabetes. J Diabetes Res. 2015;2015:189525. https://doi.org/10.1155/2015/189525 PMid:26247036 DOI: https://doi.org/10.1155/2015/189525

Chan M. Global report on diabetes. Isbn. 2016;978:6- 86. Available from: https://www.who.int/publications/i/item/9789241565257 [Last accessed on 2021 May 25].

Institute for Public Health. (IPH). National Health and Morbidity Survey (NHMS) 2019. Vol. 1. Malaysia: NCDs- Non-Communicable Diseases: Risk Factors and other Health Problems, Ministry of Health Malaysia; 2019.

National Institute of Health. Malaysian Burden of Disease and Injury Study 2009-2014; 2017. p. 2-29. Available from: https://iku.moh.gov.my/images/IKU/Document/REPORT/BOD/BOD2009-2014.pdf [Last accessed on 2021 May 25].

Reidpath DD, Soyiri I, Jahan NK, Mohan D, Ahmad B, Ahmad MP, et al. Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study. Int J Public Health. 2018;63(2):193-202. https://doi.org/10.1007/s00038-017-1072-4 PMid:29372287 DOI: https://doi.org/10.1007/s00038-017-1072-4

Fasya WW, Juni MH. Factors associated with glycaemic control among Type 2 diabetes mellitus patients. Int J Public Health Clin Sci. 2016;3(3):1-4.

Lv X, Ran X, Chen X, Luo T, Hu J, Wang Y, et al. Early-onset Type 2 diabetes. Medicine (Baltimore). 2020;99(19):e20189. https://doi.org/10.1097/MD.0000000000020189 PMid:32384512 DOI: https://doi.org/10.1097/MD.0000000000020189

Pan J, Jia W. Early-onset diabetes: An epidemic in China. Front Med. 2018;12(6):624-33. https://doi.org/10.1007/s11684-018-0669-1 PMid:30393830 DOI: https://doi.org/10.1007/s11684-018-0669-1

Bo A, Thomsen RW, Nielsen JS, Nicolaisen SK, Beck-Nielsen H, Rungby J, et al. Early-onset Type 2 diabetes: Age gradient in clinical and behavioural risk factors in 5115 persons with newly diagnosed type 2 diabetes-results from the DD2 study. Diabetes Metab Res Rev. 2018;34(3):1-9. https://doi.org/10.1002/dmrr.2968 PMid:29172021 DOI: https://doi.org/10.1002/dmrr.2968

Schweyer L. Diabetes and quality of life. Rev Infirm. 2015;64(211):45-6. https://doi.org/10.1016/j.revinf.2015.02.017 PMid:26145699 DOI: https://doi.org/10.1016/j.revinf.2015.02.017

Morgan L. Challenges and opportunities in managing Type 2 diabetes. Am Health Drug Benefits. 2017;10(4):197-200. PMid:28794823

Rao JN, Kish L. Survey sampling. Biometrics. 1969;25(3):603. DOI: https://doi.org/10.2307/2528920

Mahmood MI, Daud F, Ismail A. Glycaemic control and associated factors among patients with diabetes at public health clinics in Johor, Malaysia. Public Health. 2016;135:56-65. https://doi.org/10.1016/j.puhe.2015.07.043 PMid:26976488 DOI: https://doi.org/10.1016/j.puhe.2015.07.043

MOH. Clinical Practice Guidelines Management of Type 2 Diabetes Mellitus. Vol. 6. Singapore: MOH; 2020. p. 1-280.

Awang H, Ja’afar SM, Ishak NA, YusofZainal M, Aminuddin AM, Dollah Z. Poor glycemic control: Prevalence and risk factors among patients with Type 2 diabetes mellitus in northeast state of peninsular Malaysia. Int J Hum Health Sci. 2020;4(3):206. DOI: https://doi.org/10.31344/ijhhs.v4i3.202

Zou X, Zhou X, Ji L, Yang W, Lu J, Weng J, et al. The characteristics of newly diagnosed adult early-onset diabetes: A population-based cross-sectional study. Sci Rep. 2017;7:1-8. https://doi.org/10.1038/srep46534 DOI: https://doi.org/10.1038/srep46534

Cheah YK, Meltzer D. Ethnic differences in participation in medical check-ups among the elderly: Evidence from Malaysia. J Gen Intern Med. 2020;35(9):2680-6. https://doi.org/10.1007/s11606-020-05766-6 PMid:32185659 DOI: https://doi.org/10.1007/s11606-020-05766-6

Abdullah N, Ismail S, Ghazali SS, Juni M, Shahar H, Aziz N. Predictors of good glycemic controls among Type 2 diabetes mellitus patients in two primary health clinics, Kuala Selangor. Malaysian J Med Health Sci. 2019;15(SP3):58-64.

Sazlina SG, Mastura I, Cheong AT, Mohamad AB, Jamaiyah H, Lee PY, et al. Predictors of poor glycaemic control in older patients with Type 2 diabetes mellitus. Singapore Med J. 2015;56(5):284-90. https://doi.org/10.11622/smedj.2015055 PMid:25814074 DOI: https://doi.org/10.11622/smedj.2015055

Harding JL, Pavkov ME, Magliano DJ, Shaw JE, Gregg EW. Global trends in diabetes complications: A review of current evidence. Diabetologia. 2019;62(1):3-16. https://doi.org/10.1007/s00125-018-4711-2 PMid:30171279 DOI: https://doi.org/10.1007/s00125-018-4711-2

Huo X, Gao L, Guo L, Xu W, Wang W, Zhi X, et al. Risk of non-fatal cardiovascular diseases in early-onset versus late-onset Type 2 diabetes in China: A cross-sectional study. Lancet Diabetes Endocrinol. 2016;4(2):115-24. https://doi.org/10.1016/S2213-8587(15)00508-2 DOI: https://doi.org/10.1016/S2213-8587(15)00508-2

Soffian SSS, Ahmad SB, Chan HK, Soelar SA, Hassan MR, Ismail N. Management and glycemic control of patients with Type 2 diabetes mellitus at primary care level in Kedah, Malaysia: A statewide evaluation. PLoS One. 2019;14(10):e0223383. https://doi.org/10.1371/journal.pone.0223383 PMid:31581261 DOI: https://doi.org/10.1371/journal.pone.0223383

Alzaheb RA, Altemani AH. The prevalence and determinants of poor glycemic control among adults with Type 2 diabetes mellitus in Saudi Arabia. Diabetes Metab Syndr Obes. 2018;11:15-21. https://doi.org/10.2147/DMSO.S156214 PMid:29430192 DOI: https://doi.org/10.2147/DMSO.S156214

Piché ME, Tchernof A, Després JP. Obesity phenotypes, diabetes, and cardiovascular diseases. Circ Res. 2020;126(11):1477-500. https://doi.org/10.1161/CIRCRESAHA.120.316101 PMid:32437302 DOI: https://doi.org/10.1161/CIRCRESAHA.120.316101

Wang S, Ji X, Zhang Z, Xue F. Relationship between lipid profiles and glycemic control among patients with Type 2 diabetes in Qingdao, China. Int J Environ Res Public Health. 2020;17(15):5317. https://doi.org/10.3390/ijerph17155317 PMid:32718055 DOI: https://doi.org/10.3390/ijerph17155317

Parhofer KG. Interaction between glucose and lipid metabolism: More than diabetic dyslipidemia. Diabetes Metab J. 2015;39(5):353-62. https://doi.org/10.4093/dmj.2015.39.5.353 PMid:26566492 DOI: https://doi.org/10.4093/dmj.2015.39.5.353

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Published

2022-02-17

How to Cite

1.
Amsah N, Md Isa Z, Kassim Z. Poor Glycaemic Control and its Associated Factors among Type 2 Diabetes Mellitus Patients in Southern Part of Peninsular Malaysia: A Registry-based Study. Open Access Maced J Med Sci [Internet]. 2022 Feb. 17 [cited 2024 Dec. 3];10(E):422-7. Available from: https://oamjms.eu/index.php/mjms/article/view/8696

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Public Health Epidemiology

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